Plakoglobin: Role in Tumorigenesis and Metastasis by Zackie Aktary, Manijeh Pasdar

“…In this paper, we describe plakoglobin, its discovery and characterization, its role in regulating cell-cell adhesion, and its signaling capabilities in regulation of tumorigenesis and metastasis.…”
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TLRs, Alcohol, HCV, and Tumorigenesis by Keigo Machida

“…Synergism between alcohol and HCV may lead to liver tumorigenesis through TLR signaling.…”
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Inflammation and Inflammasomes: Pros and Cons in Tumorigenesis by Liliana R. Balahura, Aida Selaru, Sorina Dinescu, Marieta Costache

“…Over the past decade, it has been well established that tumorigenesis is affected by chronic inflammation. During this event, proinflammatory cytokines are produced by numerous types of cells, such as fibroblasts, endothelial cells, macrophages, and tumor cells, and are able to promote the initiation, progression, and metastasis of different types of cancer. …”
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ALDOA contributes to colorectal tumorigenesis and metastasis by targeting YAP by Liang Sun, Ting Lu, Linhua Jiang, Huihui Yao, Qixuan Xu, Jie Sun, Xiaoqin Yang, Songbing He, Xinguo Zhu

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PPARG Epigenetic Deregulation and Its Role in Colorectal Tumorigenesis by Lina Sabatino, Alessandra Fucci, Massimo Pancione, Vittorio Colantuoni

“…These studies have highlighted how epigenetic modifications influence PPARG gene expression in colorectal tumorigenesis. In this paper, we take a comprehensive look at the current understanding of the relationship between PPARγ and cancer development. …”
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A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis by Rolf Müller, Martin Kömhoff, Jeffrey M. Peters, Sabine Müller-Brüsselbach

“…On the contrary, a role for PPARβ/δ in tumorigenesis is less clear because there are contradictory reports in the literature. …”
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The mevalonate pathway contributes to breast primary tumorigenesis and lung metastasis by Javier Conde, Isabel Fernández‐Pisonero, L. Francisco Lorenzo‐Martín, Rocío García‐Gómez, Berta Casar, Piero Crespo, Xosé R. Bustelo

“…Furthermore, in vivo tumorigenesis experiments indicated that the two most upstream steps of this metabolic pathway [3‐hydroxy‐3‐methylglutaryl‐coenzyme A synthase 1 (HMGCS1) and 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase (HMGCR)] are important for primary tumorigenesis, angiogenesis, and cell survival in breast cancer cells. …”
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GPR55 in the tumor microenvironment of pancreatic cancer controls tumorigenesis by Dušica Ristić, Thomas Bärnthaler, Eva Gruden, Melanie Kienzl, Laura Danner, Karolina Herceg, Arailym Sarsembayeva, Julia Kargl, Rudolf Schicho

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Exploring the role and mechanisms of MAGEA4 in tumorigenesis, regulation, and immunotherapy by Weijian Zhu, Qiang Yi, Zheng Chen, Jiaqi Wang, Kui Zhong, Xinting Ouyang, Kuan Yang, Bowei Jiang, Jianing Zhong, Jinghua Zhong

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Loss of BRCA1 Spontaneously Induces the Tumorigenesis in Lacrimal Gland by Sun Eui Kim, Hye Jung Baek, Eun Jung Park, Sung Chul Lim, Sang Soo Kim

“…Further analysis revealed that tumorigenesis was accompanied by the accumulation of cyclin D1 and decreased expression of the cellular oncogenes, c-Myc, c-Jun, and c-Raf. …”
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Human Mesenchymal Stem Cells as Mediators of Breast Carcinoma Tumorigenesis and Progression by Lyndsay V. Rhodes, Matthew E. Burow

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Advances in the relationship between AP-1 and tumorigenesis, development and therapy resistance by Xinni Xue, Zhiwei Li, Jiahui Zhao, Ziyi Zhao, Zhihang Li, Yong Li, Yawen Liu, Huan He

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Chronic Stress Mediates Inflammatory Cytokines Alterations and Its Role in Tumorigenesis by Liu Z, Lei M, Bai Y

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Significance of Apoptosis in the Process of Tumorigenesis in Colorectal Mucosa and Adenomas in FAP Patients by Hildegard Weiß, Karl‐Heinz Jacobasch, Wolfgang Haensch, Brigitte Streller, Brigitte Hieke

“…A connection between proliferation and apoptosis was observed in mucosa and TVA. The process of tumorigenesis is characterised by a stepwise increase in resistance to apoptosis followed by an increase in cycling cells.…”
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EI24 Suppresses Tumorigenesis in Pancreatic Cancer via Regulating c-Myc by Yi Zang, Lei Zhu, Tong Li, Qi Wang, Juanjuan Li, Yuting Qian, Lumin Wei, Mingping Xie, Wen-Hao Tang, Xu Liu, Ying Zhu, Lifu Wang

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Akt/p27kip1 Pathway Is Not Involved in Human Insulinoma Tumorigenesis by Adriana Graciela Díaz, Andrea Paes de Lima, Paula Garibaldi, Maria de los Milagros Rubio, Florencia García, Marta Kral, Oscar D. Bruno

“…Our data seem to suggest that the Akt pathway is not involved in human insulinoma tumorigenesis.…”
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Impact of glycolysis enzymes and metabolites in regulating DNA damage repair in tumorigenesis and therapy by Fengyao Sun, Wen Li, Ruihang Du, Mingchan Liu, Yi Cheng, Jianxing Ma, Siyuan Yan

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The role of cell cycle-related genes in the tumorigenesis of adrenal and thyroid neuroendocrine tumors by Ekaterina Filipovich, Ekaterina Gorodkova, Anastasia Shcherbakova, Walaa Asaad, Sergey Popov, Galina Melnichenko, Natalya Mokrysheva, Marina Utkina

“…The molecular mechanisms underlying adrenal and thyroid neuroendocrine tumors, including their tumorigenesis, progression, and metastasis, involve unique pathways regulating cell cycle progression. …”
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Activation and Expression of Peroxisome Proliferator-Activated Receptor Alpha Are Associated with Tumorigenesis in Colorectal Carcinoma by Tatsuya Morinishi, Yasunori Tokuhara, Hiroyuki Ohsaki, Emi Ibuki, Kyuichi Kadota, Eiichiro Hirakawa

“…Peroxisome proliferator-activated receptor alpha (PPAR-α) belongs to the PPAR family and plays a critical role in inhibiting cell proliferation and tumorigenesis in various tumors. However, the role of PPAR-α in colorectal tumorigenesis is unclear. …”
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Interplay of Transcriptomic Regulation, Microbiota, and Signaling Pathways in Lung and Gut Inflammation-Induced Tumorigenesis by Beatriz Andrea Otálora-Otálora, César Payán-Gómez, Juan Javier López-Rivera, Natalia Belén Pedroza-Aconcha, Sally Lorena Arboleda-Mojica, Claudia Aristizábal-Guzmán, Mario Arturo Isaza-Ruget, Carlos Arturo Álvarez-Moreno

Subjects: “…inflammation-induced tumorigenesis models…”
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