Role of Ultrasound-guided Tru-cut Needle Biopsy in the Diagnosis of Suspicious Breast Masses at South Valley University Hospitals by Ghada M. Abd ElRazik, Dalia Besharii Hamada, Mohammed M. Mubarak, Ahmed M. Khalaf-Awad

“…Conclusion: Ultrasound-guided Tru-cut needle biopsy is vital for diagnosing breast tumors, demonstrating high sensitivity, specificity, and accuracy, supporting its role in timely and precise breast cancer diagnosis, influencing patient management and treatment decisions.…”
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Two-photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure by Zaneta D. Musimbi, Arkadi Kundik, Jürgen Krücken, Anja E. Hauser, Sebastian Rausch, Peter H. Seeberger, Raluca Niesner, Ruth Leben, Susanne Hartmann

“…Artemisinin derivatives (ARTs)—artesunate, artemether, and dihydroartemisinin—are standard malaria treatments and are also known to influence the energy metabolism of parasites, tumors, and immune cells. Herein, we explore the potential of ARTs to influence ascariasis either by directly targeting larvae or indirectly by modifying macrophage responses. …”
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The Clinical Values of Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Blood and Thyroid Nodules by Ayfer Altas, Fatih Kuzu, Dilek Arpaci, Mustafa Unal, Murat Can, Figen Barut, Furuzan Kokturk, Sevil Uygun Ilikhan, Taner Bayraktaroglu

“…IGF-1 plays a role in the pathogenesis of various tumors with its mutagenic and antiapoptotic properties. …”
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Towards Personalized Radiotherapy in Pelvic Cancer: Patient-Related Risk Factors for Late Radiation Toxicity by Anna C. Nuijens, Arlene L. Oei, Nicolaas A. P. Franken, Coen R. N. Rasch, Lukas J. A. Stalpers

“…This narrative review examines patient-related determinants of late toxicity following external beam radiotherapy for pelvic tumors, with a focus on prostate and cervical cancer patients. …”
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The effect of ileostomy closure timing on low anterior resection syndrome in patient who underwent low anterior resection for rectal cancer by Hemn Hussain Kaka Ali, Qalandar Hussein Abdulkarim, Karzan Seerwan, Barham M. M .Salih, Omar H Ghalib Hawramy, Dara Ahmed Mohammed, Syamand Orhaman Ahmed

“…Majority of patients were overweight (21, 42%). The distance of tumors from the anal verge were less than 10 cm in (31,62%). …”
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KaRhab: an international online registry for cardiac rhabdomyomas by Vera-Maria Herrmann, Maria Arelin, Caroline G. Bergner, Julia Herrmann, Paula Janz, Henriette Kiep, Annika Mueller, Steffen Syrbe, Robert Wagner, Bardo Wannenmacher, Nadine Wolf, Michael Weidenbach, Vincent Strehlow

“…Abstract Background Cardiac rhabdomyoma (RHM) is considered one of the most frequent benign heart tumors in children. However, encounters with cardiac RHM in clinical practice remain rare. …”
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Transcriptional Targeting of Mature Dendritic Cells with Adenoviral Vectors via a Modular Promoter System for Antigen Expression and Functional Manipulation by Ilka Knippertz, Andrea Deinzer, Jan Dörrie, Niels Schaft, Dirk M. Nettelbeck, Alexander Steinkasserer

“…To specifically target dendritic cells (DCs) to simultaneously express different therapeutic transgenes for inducing immune responses against tumors, we used a combined promoter system of adenoviral vectors. …”
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Chronic Gastroesophageal Reflux Dysregulates Proteostasis in Esophageal Epithelial CellsSummary by Kodisundaram Paulrasu, Ravindran Caspa Gokulan, Wael El-Rifai, Zhibin Chen, Jianwen Que, Timothy C. Wang, Olivier G. Boutaud, Karoline Briegel, Sergey I. Dikalov, Monica T. Garcia-Buitrago, Alexander I. Zaika

“…GERD can raise the risk of multiple serious complications including esophageal tumors. At the molecular levels, GERD-affected tissues are characterized by strong oxidative stress and the formation of reactive isolevuglandins (isoLGs). …”
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Diabetes Mellitus, Extreme Insulin Resistance, and Hypothalamic-Pituitary Langerhans Cells Histiocytosis by Mathilde Sollier, Marine Halbron, Jean Donadieu, Ahmed Idbaih, Fleur Cohen Aubart, Corinne Vigouroux, Martine Auclair, Olivier Bourron, Marie Bastin, Géraldine Béra, Philippe Touraine, Jacques Young, Héléna Mosbah, Agnès Hartemann, Fabrizio Andreelli, Chloé Amouyal

“…Each episode of hyperglycemia appeared to be correlated with tumoral activity and increase in serum anti-insulin receptor antibodies and appeared to be improved when the disease was controlled by chemotherapy. …”
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Integrated Bioinformatic Analysis Identifies Networks and Promising Biomarkers for Hepatitis B Virus-Related Hepatocellular Carcinoma by Yun Ji, Yue Yin, Weizhen Zhang

“…Here, three microarray datasets, totally containing 170 tumoral samples and 181 adjacent normal tissues from the liver of patients suffering from HBV-related HCC assembled from the Gene Expression Omnibus (GEO) database, were subjected to integrated analysis of differentially expressed genes (DEGs). …”
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The opposite association of HRAS and KRAS mutations with clinical variables of bladder cancer by M. P. Smal, A. I. Rolevich, T. N. Nabebina, S. A. Krasny, R. I. Goncharova

“…However, when analyzed separately, HRAS and KRAS mutations were for the first time shown to be associated with the opposite clinical parameters of bladder cancer: HRAS mutations were significantly associated with low-stage low-grade papillary tumors of a small size (р < 0.05), whereas KRAS mutations were associated with non-papillary urothelial carcinomas and the presence of metastasis (р < 0.05). …”
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Advancements in nanosensors for cancer detection by Dinesh Bhatia, Tania Acharjee, Monika Bhatia

“…Improved patient outcomes and early intervention are anticipated using the i-Genbox, a colorimetric sensor based on LAMP technology, and DNA-SWCNT-based sensors that further improve biomarker identification for gynecologic tumors.…”
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Importance of complement system components in ovarian endometriomas. A comparative cohort study by Anna V. Chizhova, Elena V. Kudryavtseva, Larisa G. Polushina, Maksim A. Kopenkin

“…There are specific ultrasound criteria for this type of endometriosis; however, in some cases, differential diagnosis from other ovarian tumors is challenging. Aim. To compare the levels of complement system components (C3 and C4) in women with endometriomas and other benign ovarian lesions and to determine the possibilities of using these indicators for differential diagnosis. …”
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Computational predictions of magnetic resonance acoustic radiation force imaging for breast cancer focused ultrasound therapy by Chloe K. Nelson, Michelle Kline, Allison Payne, Christopher R. Dillon

“…Those simulations are compared to clinical magnetic resonance acoustic radiation force imaging (MR-ARFI) data collected during in vivo treatment of breast tumors.Methods The focal location was evaluated before MRgFUS treatment with MR-ARFI in five patients. …”
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Therapeutic Decision Making in Hepatocellular Carcinoma According to Age and Child–Pugh Class: A Nationwide Cohort Analysis in South Korea by Sunmin Park, Chai Hong Rim, Young Kul Jung, Won Sup Yoon

“…In unfavorable conditions, surgical resection was less favored in patients with single tumors, and no treatment was preferred in patients with PVT.…”
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Loss of SNHG4 Attenuated Spinal Nerve Ligation-Triggered Neuropathic Pain through Sponging miR-423-5p by Xia Pan, Cheng Shen, Yayi Huang, Long Wang, Zhongyuan Xia

“…Increasing noncoding RNAs have been implicated in neuropathic pain development. lncRNAs have been recognized as significant regulators of neuropathic pain. lncRNA Small Nucleolar RNA Host Gene 4 (SNHG4) is associated with several tumors. However, the molecular mechanisms of SNHG4 in neuropathic pain remain barely documented. …”
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Efficacy and Safety of Endoscopic Submucosal Dissection for Dysplasia in Ulcerative Colitis Patients: A Systematic Review and Meta-Analysis by Qi-Shan Zeng, Zhi-Jing Zhao, Jiao Nie, Min Zou, Jia-Hui Yang, Jin-Zhi Zhang, Hua-Tian Gan

“…The rates of metachronous tumors and additional surgery after ESD were 6% and 10%, respectively. …”
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Screening of Active Components and Key Targets of Radix Codonopsis in the Treatment of Gastric Cancer by Lijun Tang, Jinhui Chen, Jin Yin, Mingli Fang

“…The incidence and mortality of gastric cancer in China ranks second among malignant tumors in the country. At present, the main treatment method of gastric cancer is still surgical resection combined with chemotherapy. …”
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Plexin C1 Marks Liver Cancer Cells with Epithelial Phenotype and Is Overexpressed in Hepatocellular Carcinoma by Gorkem Odabas, Metin Cetin, Serdar Turhal, Huseyin Baloglu, A. Emre Sayan, Tamer Yagci

“…Staining of HCC and nontumoral liver tissues with PE4 showed a membrane-localized overexpression of Plexin C1 in tumors (p=0.0118). In addition, this expression was correlated with the histological grades of HCC cases. …”
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Utilization of Oncotype DX in an Inner City Population: Race or Place? by Amber A. Guth, Susan Fineberg, Kezhen Fei, Rebeca Franco, Nina A. Bickell

“…Oncotype DX, a 21-gene-array analysis, can guide chemotherapy treatment decisions for women with ER+ tumors. Of 225 ER+ women participating in a patient assistance trial, 23% underwent Oncotype DX testing: 31% of whites, 21% of blacks, and 14% of Hispanics (P=0.04) were tested. …”
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