Progression of Luminal Breast Tumors Is Promoted by Ménage à Trois between the Inflammatory Cytokine TNFα and the Hormonal and Growth-Supporting Arms of the Tumor Microenvironment by Polina Weitzenfeld, Nurit Meron, Tal Leibovich-Rivkin, Tsipi Meshel, Adit Ben-Baruch

“…Here, we show that together with representatives of other important arms of the tumor microenvironment, estrogen (hormonal) and EGF (growth-supporting), TNFα potently induced metastasis-related properties and functions in luminal breast tumor cells, representing the most common type of breast cancer. …”
Get full text

Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma by Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Shohei Kohno, Shiro Ohue, Shirabe Matsumoto, Satoshi Suehiro, Daisuke Yamashita, Saya Ozaki, Hideaki Watanabe, Hajime Yano, Hisaaki Takahashi, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda

“…These results imply the significance of GSCs with high levels of CD44 expression in the tumor periphery compared to the core, not only in tumor invasion but also rapid tumor progression and short survival in patients with GBM.…”
Get full text

TFE3-rearranged perivascular epithelioid cell tumors of the head and neck with rare fusion partners: clues to the differential diagnosis between benign and malignant tumors by Yuka Takahashi, Akihiko Yoshida, Seiichi Yoshimoto, Shigenobu Suzuki, Satsuki Kishikawa, Ayaka Mitsui, Eijitsu Ryo, Yuki Kojima, Kan Yonemori, Yasushi Yatabe, Taisuke Mori

Subjects: “…Perivascular epithelioid cell tumor…”
Get full text

Heterogeneity of Genetic Landscapes in Salivary Gland Tumors and Their Critical Roles in Current Management by Anam YOUSAF, Sarina SULONG, Baharudin ABDULLAH, Norhafiza Mat LAZIM

Subjects: “…salivary glands tumor…”
Get full text

Alpha/beta values in pediatric medulloblastoma: implications for tailored approaches in radiation oncology by Danny Jazmati, Dennis Sohn, Juliane Hörner-Rieber, Nan Qin, Edwin Bölke, Jan Haussmann, Rudolf Schwarz, Niklas David Niggemeier, Arndt Borkhardt, Florian Babor, Triantafyllia Brozou, Melissa Felek, Balint Tamaskovics, Patrick Melchior, Thomas Beez, Beate Timmermann, Marc Remke, Stefanie Corradini, Rémi Till Schulz, Ronja-Linda Preugschas, Wilfried Budach, Christiane Matuschek

Subjects: Get full text

Lipoma of the Ischiorectal Fossa: A Rare Case Report by Djavan Khubanov, Kamala Gasimova

Subjects: Get full text

Effect of neutrophils on tumor immunity and immunotherapy resistance with underlying mechanisms by Jiali Yao, Linlin Ji, Guang Wang, Jin Ding

Subjects: Get full text

Carbon Material Hybrid Construction on an Aptasensor for Monitoring Surgical Tumors by Renyuan Ma, Subash C. B. Gopinath, Thangavel Lakshmipriya, Yeng Chen

“…Carcinoembryonic antigen (CEA) is a glycoprotein, one of the common tumor biomarkers, found at low levels in body fluids. …”
Get full text

Gouty tumor-like changes of the patella: A case report by Hongyan Yao, Fangdi Gong, Sheng Zhou, Ping Wang

Get full text

Treatment Patterns of Long-Acting Somatostatin Analogs for Neuroendocrine Tumors by Callisia N. Clarke, Paul Cockrum, Thomas J.R. Beveridge, Michelle Jerry, Donna McMorrow, Anh Thu Tran, Alexandria T. Phan

“…**Background:** Long-acting somatostatin analog therapy (LA-SSA) is recommended as first-line therapy for treatment of unresectable or metastatic neuroendocrine tumors (NETs). Understanding treatment sequencing and dosing patterns of LA-SSA is essential for clinical decision-making to provide value-based management of NETs. …”
Get full text

Modulation of Tumor Tolerance in Primary Central Nervous System Malignancies by Theodore S. Johnson, David H. Munn, Bernard L. Maria

“…Central nervous system tumors take advantage of the unique immunology of the CNS and develop exquisitely complex stromal networks that promote growth despite the presence of antigen-presenting cells and tumor-infiltrating lymphocytes. …”
Get full text

Multicentric Giant Cell Tumor of Bone: Synchronous and Metachronous Presentation by Reiner Wirbel, Frank Blümler, Dirk Lommel, Guido Syré, Veit Krenn

“…A 27-year-old man treated 2.5 years ago for synchronous multicentric giant cell tumor of bone located at the right proximal humerus and the right 5th finger presented now with complaints of pain in his right hip and wrist of two-month duration. …”
Get full text

Dynamic roles of tumor-infiltrating B lymphocytes in cancer immunotherapy by Shishengnan Song, Chong Wang, Yangchao Chen, Xiaorong Zhou, Yi Han, Haijian Zhang

Subjects: “…Tumor-infiltrating B cells…”
Get full text

Malignant Peripheral Nerve Sheath Tumor: MRI and CT Findings by K. O. Kragha

“…Motor weakness, central enhancement, and immunohistochemistry may assist in the diagnosis of MPNST and differentiation between benign peripheral nerve sheath tumor (BPNST) and MPNST.…”
Get full text

Esophageal Gastrointestinal Stromal Tumor: Diagnostic Complexity and Management Pitfalls by Charalampos G. Markakis, Eleftherios D. Spartalis, Emmanouil Liarmakopoulos, Evangelia G. Kavoura, Periklis Tomos

“…Gastrointestinal stromal tumors of the esophagus are rare. Case Presentation. …”
Get full text

Directional entropy based model for diffusivity-driven tumor growth by Marcelo E. de Oliveira, Luiz M. G. Neto

“…In this work, we present and investigate a multiscale model to simulate 3D growth of glioblastomas (GBMs) that incorporates features of the tumor microenvironment and derives macroscopic growth laws from microscopic tissue structure information. …”
Get full text

Tumor Biomarker In-Solution Quantification, Standard Production, and Multiplex Detection by Nicole C. Japp, Joshua J. Souchek, Aaron R. Sasson, Michael A. Hollingsworth, Surinder K. Batra, Wade M. Junker

“…The diagnosis and monitoring of cancer have been facilitated by discovering tumor “biomarkers” and methods to detect their presence. …”
Get full text

Reproductive effects of the tumor necrosis factor (TNF) deficiency in mice by S. O. Maslennikova, G. V. Kontsevaya, M. A. Zolotykh, M. V. Anisimova, N. A. Feofanova, M. P. Moshkin, S. A. Nedospasov, L. A. Gerlinskaya

Subjects: “…tumor necrosis factor (tnf)…”
Get full text

Implications of Therapy-Induced Selective Autophagy on Tumor Metabolism and Survival by Luke R. K. Hughson, Vincent I. Poon, Jaeline E. Spowart, Julian J. Lum

“…Accumulating evidence indicates that therapies designed to trigger apoptosis in tumor cells cause mitochondrial depolarization, nuclear damage, and the accumulation of misfolded protein aggregates, resulting in the activation of selective forms of autophagy. …”
Get full text

The heterogeneity of NOTCH1 to tumor immune infiltration in pan-cancer by XiaoJun Duan, Rihan Wu, Mingyang Zhang, Kexin Li, Lei Yu, Huirong Sun, Xingxia Hao, Changshan Wang

Subjects: Get full text