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4-Aminoquinoline as a privileged scaffold for the design of leishmanicidal agents: structure–property relationships and key biological targets
Published 2025-01-01“…Leishmaniasis is one of the most important neglected tropical diseases, with more than two million new cases annually. …”
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Active case detection and treatment of malaria in pregnancy using LAMP technology (LAMPREG): a pragmatic randomised diagnostic outcomes trial—study protocol
Published 2022-07-01“…The study results will be shared with the institutions and stakeholders such as the Ethiopia Ministry of Health, the Foundation for Innovative Diagnostics, WHO’s Multilateral initiative on Malaria - Tropical Diseases Research (TDR-MIM), Roll Back Malaria and the Malaria in Pregnancy Consortium. …”
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Prevalence, Intensity, and Associated Factors of Schistosoma mansoni among School Children in Northwest Ethiopia
Published 2020-01-01“…Schistosomiasis is one of the Neglected Tropical Diseases in Ethiopia, and its burden may show variations from time to time across different regions. …”
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306
Towards global elimination of lymphatic filariasis: a systematic review of the application of spatial epidemiological methods to enhance surveillance and support elimination progra...
Published 2024-05-01“…Background In recent decades, spatial epidemiology has increasingly been used to study neglected tropical diseases (NTDs). Spatial methods are particularly relevant when transmission is strongly driven by sociodemographic and environmental factors, resulting in heterogeneous disease distribution. …”
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In silico design of an epitope-based vaccine ensemble for fasliolopsiasis
Published 2025-01-01“…Finding successful vaccination antigen combinations from these huge number of genes/proteins in the available omics datasets is the key in combating these neglected tropical diseases. In the present study, we developed an in silico workflow to select antigens for composing a chimeric vaccine, which could be a significant technique for developing a fasciolopsiasis vaccine that prevents the parasite from causing serious harm.Results and discussionThis chimeric vaccine can now be tested experimentally and compared to other vaccine candidates to determine its potential influence on human health. …”
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Defining indicators for disease burden, health outcomes, policies and barriers and facilitators to health services for migrant populations in the Middle East and North African regi...
Published 2024-07-01“…This protocol describes a suite of seven systematic reviews that aim to identify, appraise and synthesise the available evidence on the burden and health outcomes, policies and access (barriers and facilitators) related to these mobile populations in the region.Methods Seven systematic reviews will cover three questions to explore the: (1) burden and health outcomes, (2) policies and (3) healthcare barriers and facilitators for the following seven disease areas in migrants in the MENA region: tuberculosis, HIV and hepatitis B and C, malaria and neglected tropical diseases, diabetes, mental health, maternal and neonatal health, and vaccine-preventable diseases. …”
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Spacetime modeling of mortality by infectious and parasitic diseases in Brazil: a 20-year ecological and population-based study
Published 2025-01-01“…The leading causes of death included acute respiratory infections ( n = 1,130,069; 52.49%), septicemia ( n = 289,817; 13.46%), human immunodeficiency virus/acquired immunodeficiency syndrome ( n = 232,892; 10.82%), tuberculosis ( n = 104,121; 4.84%), and neglected tropical diseases such as Chagas disease ( n = 94,788; 4.40%) and schistosomiasis ( n = 10,272; 0.48%). …”
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Efficiency of Automated Viral RNA Purification for Pediatric Studies of Dengue and Zika in Hyperendemic Areas
Published 2023-01-01“…The local application of this technology in the study of tropical diseases, such as dengue and zika, is beginning to be tested. …”
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Prevalence of S. mansoni Infection and Associated Risk Factors among School Children in Guangua District, Northwest Ethiopia
Published 2022-01-01“…Schistosomiasis is one of the neglected tropical diseases and is prevalent in tropics. It causes morbidity and mortality in developing countries including Ethiopia. …”
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314
High Seropositivity of Brucella melitensis Antibodies among Pregnant Women Attending Health Care Facilities in Mwanza, Tanzania: A Cross-Sectional Study
Published 2023-01-01“…Brucellosis is one of the most prevalent zoonotic neglected tropical diseases across the globe. Brucella melitensis (B. melitensis), the most pathogenic species is responsible for several pregnancy adverse outcomes in both humans and animals. …”
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Dog Bites and Rabies in the Eastern Region of Ghana in 2013–2015: A Call for a One-Health Approach
Published 2018-01-01Get full text
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Frequent Recurrences of Genital Herpes Are Associated with Enhanced Systemic HSV-Specific T Cell Response
Published 2020-01-01Get full text
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Anatomical and pathological findings in longlived female Bubalus bubalis
Published 2023-11-01“…This species, considered resistant to tropical diseases, is resilient enough to survive up to 19 years, some with severe damage to vital organs. …”
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