Drosophila Mutant Model of Parkinson’s Disease Revealed an Unexpected Olfactory Performance: Morphofunctional Evidences by Francescaelena De Rose, Valentina Corda, Paolo Solari, Patrizia Sacchetti, Antonio Belcari, Simone Poddighe, Sanjay Kasture, Paolo Solla, Francesco Marrosu, Anna Liscia

“…Parkinson’s disease (PD) is one of the most common neurodegenerative diseases characterized by the clinical triad: tremor, akinesia, and rigidity. Several studies have suggested that PD patients show disturbances in olfaction as one of the earliest, nonspecific nonmotor symptoms of disease onset. …”
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Hepatic encephalopathy: pathogenesis, clinical presentation, diagnostics, treatment by Ch. S. Pavlov, I. V. Damulin, V. T. Ivashkin

“…Cognitive (varying from the minimal changes to coma) and motor (muscles stiffness, baryphonia, tremor, etc.) disorders prevail in the clinical presentation. …”
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Krisis Tiroid pada Wanita Multipara Usia 42 Tahun by Garri Prima Decroli, Eva Decroli

“…Dilaporkan seorang wanita multipara 42 tahun yang telah dikenal hipertiroid datang dengan penurunan kesadaran sejak 1 hari sebelum masuk rumah sakit, usia kehamilan 20 minggu. sebelumnya pasien mengeluhkan palpitasi, demam, berkeringat, tremor, diare, dan sesak nafas. Berdasarkan pemeriksaan fisik, pasien tampak delirium, dengan tekanan darah 110/50 mmHg, nadi 115 kali/menit, dan suhu 38,4oC. …”
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Enhanced bioavailability of Quercetin-loaded niosomal in situ gel for the management of Parkinson’s disease by Abhishek A. Revankar, Archana S. Patil, Reshma Karishetti, Krutuja R. Chougule, Priyanka Patil, Abhijit Salokhe

“…BackgroundParkinson’s disease (PD) is the second most prevalent neurological disorder, characterized by motor symptoms such as tremor and rigidity due to the degeneration of dopaminergic neurons in the substantia nigra. …”
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Serotonin Syndrome after Sertraline Overdose in a Child: A Case Report by Joana Grenha, Ana Garrido, Hernani Brito, Maria José Oliveira, Fátima Santos

“…At admission, she had marked agitation, visual hallucinations, diaphoresis, flushing, and tremor. She had fever and periods of hypertension. …”
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Cognition Deficits in Parkinson’s Disease: Mechanisms and Treatment by Congcong Fang, Longqin Lv, Shanping Mao, Huimin Dong, Baohui Liu

“…Parkinson’s disease (PD) is the second most common progressive neurodegenerative disorder mainly in middle-elderly population, which represents diverse nonmotor symptoms (NMS) besides such well-documented motor symptoms as bradykinesia, resting tremor, rigidity, and postural instability. With the advancement of aging trend worldwide, the global prevalence of PD is mounting up year after year. …”
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Neuroborreliosis with encephalitis: a broad spectrum of clinical manifestations by Dominica Hudasch, Franz Felix Konen, Nora Möhn, Lea Grote-Levi, Ulrich Wurster, Gabriel Welte, Josef Conzen, Nima Mahmoudi, Thomas Skripuletz, Philipp Schwenkenbecher

“…Clinical manifestations ranged from cognitive impairments resembling primary dementia to movement disorders mimicking Parkinson's disease, tremor, and epileptic seizures. In 5/7 patients (71%) they occurred between August to September. …”
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Clinical features and progression of Parkinson's disease with LRRK2 variants: A prospective study by Tingwei Song, Xiaoxia Zhou, Chunyu Wang, Heng Wu, Xinxiang Yan, Jifeng Guo, Beisha Tang, Lifang Lei, Qian Xu, Parkinson's Disease & Movement Disorders Multicenter Database and Collaborative Network in China (PD‐MDCNC)

“…Results The LRRK2‐G2385R variant showed slower progression in tremor symptoms and excessive daytime sleepiness compared with IPD. …”
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Confirmatory Factor Analysis of the Motor Unified Parkinson’s Disease Rating Scale by Stefanie D. Vassar, Yvette M. Bordelon, Ron D. Hays, Natalie Diaz, Rebecca Rausch, Cherry Mao, Barbara G. Vickrey

“…A model with five factors (gait/posture, tremor, rigidity, bradykinesia affecting the left extremities, bradykinesia affecting the right extremities) fit the data well, with similar results for OFF and ON states. …”
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Case report: Dysphonia associated with high-dose cytarabine therapy by Ling Ma, Niya Huang, Haixi Zhang, Jia Liu, Zhiqing Zhang

“…Additionally, it can cause central nervous system (CNS) symptoms, which include hoarseness, ataxic tremor, ataxic gait, nystagmus, dysmetria, and dysdiadochokinesia. …”
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Data Clustering Improves Siamese Neural Networks Classification of Parkinson’s Disease by Mohamed Shalaby, Nahla A. Belal, Yasser Omar

“…Parkinson’s disease (PD) is a clinical neurodegenerative disease having symptoms like tremor, rigidity, and postural disability. According to Harvard, about 60,000 of American citizens are diagnosed with PD yearly, with more than 10 million people infected worldwide. …”
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Clothianidin and Thiacloprid Mixture Administration Induces Degenerative Damage in the Dentate Gyrus and Alteration in Short-Term Memory in Rats by Alejandra Mora-Gutiérrez, Jorge Guevara, Carmen Rubio, Minerva Calvillo-Velasco, Daniela Silva-Adaya, Socorro Retana-Márquez, Blanca Espinosa, Carmen Martínez-Valenzuela, Moisés Rubio-Osornio

“…Chronic exposure to neonicotinoids in humans is related to autism, memory loss, and finger tremor. In this article, we evaluate the effect of subchronic oral administration of two neonicotinoids in the same mixture: clothianidin and thiacloprid. …”
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The case of Kinsburn’s Encephalopathy in a child with neuroblastoma of posterior mediastinum by T.I. Stetsenko, H.M. Fedushka, S.O. Rebenkov, T.P. Ivanova

“…Neurological status: eyes opsoclonus, truncal tremor, ataxia of the cerebellum. There were also changes in behavior and a sleep disorder. …”
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Early Infantile Epileptic Encephalopathy in an STXBP1 Patient with Lactic Acidemia and Normal Mitochondrial Respiratory Chain Function by Dong Li, Elizabeth Bhoj, Elizabeth McCormick, Fengxiang Wang, James Snyder, Tiancheng Wang, Yan Zhao, Cecilia Kim, Rosetta Chiavacci, Lifeng Tian, Marni J. Falk, Hakon Hakonarson

“…We report a 7-year-old boy who presented for diagnostic evaluation of intractable epilepsy, episodic ataxia, resting tremor, and speech regression following a period of apparently normal early development. …”
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A case of neuronal intranuclear inclusion disease (NIID) presenting with hydrocephalus-like clinical features: case report by Yonghong Wang, Yongxiang Li, Wei Pan, Yuezhen Shen, Junxia Li, Ying Liu, Yuhua Peng, Shulai Zhu

“…Seven years previously, she began to experience tremors in both hands, which occurred at rest and while holding objects; this was accompanied by urinary incontinence. …”
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Whole-genome association studies of distribution of developmental abnormalities and other breeding-valuable qualitative traits in offspring of the Russian large-white boars by A. A. Traspov, O. V. Kostyunina, A. A. Belous, T. V. Karpushkina, N. A. Svejenceva, N. A. Zinovieva

“…After GWAS, we obtained 24 alleles in 11 corresponding genes  (P < 0.1) in the genome of pigs, which are significantly correlated with traits of developmental abnormalities such as anal atresia (ARMC7,FANCC,RND3,ENSSSCG00000017216), limb problems (PAWR,NTM,OPCML,ENSSSCG00000040250, ENSSSCG00000017018) and tremor of piglets (RIC3,ENSSSCG00000032665). Also, co-expression of the NTM,OPCMLand  RND3genes was revealed. …”
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Manganese Inhalation as a Parkinson Disease Model by José Luis Ordoñez-Librado, Verónica Anaya-Martínez, Ana Luisa Gutierrez-Valdez, Laura Colín-Barenque, Enrique Montiel-Flores, Maria Rosa Avila-Costa

“…After 5 months of Mn mixture inhalation, striatal dopamine content decreased 71%, the SNc showed important reduction in the number of TH-immunopositive neurons, mice developed akinesia, postural instability, and action tremor; these motor alterations were reverted with L-DOPA treatment. …”
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Impact of Deep Brain Stimulation on Daily Routine Driving Practice in Patients with Parkinson’s Disease by Carsten Buhmann, Eik Vettorazzi, Christian Oehlwein, Fred Rikkers, Monika Poetter-Nerger, Alessandro Gulberti, Christian Gerloff, Christian K. Moll, Wolfgang Hamel

“…H&Y “on” and UPDRS III “off” scores at time of surgery were lower in pre- and postoperative active than in inactive drivers. Tremor and akinesia were less frequent reasons to quit driving after than before DBS surgery. …”
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Pimavanserin Treatment for Parkinson’s Disease Psychosis in Clinical Practice by Khashayar Dashtipour, Fiona Gupta, Robert A. Hauser, Cherian A. Karunapuzha, John C. Morgan

“…In addition, effective pharmacotherapy for PDP may also facilitate the use of other medications needed to treat neurological symptoms of PD (e.g., tremor, bradykinesia, and dyskinesia), although they may also have adverse effects that contribute to symptoms of PDP.…”
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Comparing Balance Performance on Force Platform Measures in Individuals with Parkinson’s Disease and Healthy Adults by Cathy C. Harro, Amanda Kelch, Cora Hargis, Abigail DeWitt

“…All three FP tests distinguished between PD subtypes, with the Posture Gait Instability subtype demonstrating poorer balance performance than Tremor Dominant subtype. Conclusion. These findings suggest FP measures provide clinically meaningful, diagnostic information in the examination of balance impairments in individuals with PD. …”
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