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6721
A comparison of development methods used to define portion sizes in food-based dietary guidelines around the world
Published 2025-02-01“…Recommended portions in grams per day were extracted for 15 food categories to enable comparison across development methods and global regions.ResultsFBDGs from 96 countries were accessed and translated. Of these, n = 83 were based on consensus/review, n = 15 used data-based approaches, and n = 30 included other minor calculations. …”
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6722
N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1
Published 2024-12-01“…Silencing METTL3/YTHDF1 weakened the translation of GLIS1 and disrupted the balance between FAO and glycolysis. …”
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6723
Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review
Published 2025-02-01“…The coupling of phytotherapy with novel drug delivery systems such as nanoparticles, liposomes, nanotubes, quantum dots, etc. can help translate these beneficial effects of phytochemicals into clinical practice. …”
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6724
The Effect of Kidney Transplantation on Pulmonary Hypertension in End-stage Kidney Disease Patients on Hemodialysis
Published 2024-12-01“…There is also improvement in overall cardiac functions, serum hemoglobin, and calcium levels. This translates to better physical endurance as evidenced by improvement in NYHA class post KT.…”
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6725
Bridging animal models and humans: neuroimaging as intermediate phenotypes linking genetic or stress factors to anhedonia
Published 2025-01-01“…Conclusions This cross-species validation suggests that these neuroimaging patterns may serve as robust intermediate phenotypes, linking etiology to anhedonia and facilitating the translation of findings from animal models to humans with depression and other psychiatric disorders.…”
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6726
Sequential or simultaneous-integrated boost in early-stage breast cancer patients: trade-offs between skin toxicity and risk of compromised coverage
Published 2025-01-01“…Rotations of 0.5°, 1°, and 2° coupled with translationals of 0.5 mm, 1.0 mm, and 2.0 mm were applied along three orthogonal axes. …”
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6727
The Probe for Renal Organic Cation Secretion (4-Dimethylaminostyryl)-N-Methylpyridinium (ASP+)) Shows Amplified Fluorescence by Binding to Albumin and Is Accumulated In Vivo
Published 2022-01-01“…The renal pattern of fluorescence observed from ASP+ in vivo is likely affected by the local concentration of albumin, and quantification of ASP+ fluorescent signals in vivo cannot be directly translated to ASP+ concentrations.…”
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6728
Effect of immunomodulation on cardiac remodelling and outcomes in heart failure: a quantitative synthesis of the literature
Published 2020-06-01“…While these benefits did not translate into a significant improvement in mortality, our analysis suggests that larger studies of targeted immunomodulation are needed to understand the true benefits.…”
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6729
Global trends in importance of 24-hour movement behaviors to pediatric health: implications for South Korea
Published 2025-01-01“…Korean health authorities have also responded to this need by releasing a translated report of the WHO guidelines for physical activity and sedentary behavior as well as the 2024 update of the Physical Activity Guidelines for Koreans. …”
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6730
Protecting the American dream for socially vulnerable families: An evaluation of state-level policies to improve housing security and protect mobile home communities
Published 2025-06-01“…Among mobile home park residents, fear of retaliation from property owners, park management, and oversight agencies remained a significant barrier to policy effectiveness despite the new protections offered by the state-level policies. Conclusions: Translation of policies into practice takes time and resources. …”
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6731
Exploitation of Unconventional CD8 T-Cell Responses Induced by Engineered Cytomegaloviruses for the Development of an HIV-1 Vaccine
Published 2025-01-01“…However, CMVs are highly species-adapted viruses and it is yet to be shown whether the success of RhCMV68-1 can be translated into an HCMV ortholog for humans. Despite some safety concerns regarding using HCMV as a vaccine vector in humans, there is a vision of immune programming of HCMV to induce pathogen-tailored CD8<sup>+</sup> T-cells effective against HIV-1 and other life-threatening diseases.…”
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6732
YHSeqY3000 panel captures all founding lineages in the Chinese paternal genomic diversity database
Published 2025-01-01“…Conclusions This work successfully integrated Y-chromosome-related basic genomic science with forensic and anthropological translational applications, emphasizing the necessity of comprehensively characterizing Y-chromosome genomic diversity from genomically under-representative populations. …”
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6733
Comparative transcriptomic analysis of primary endometrial cancer and bone metastatic cancer: metastasis-associated genes and abnormal cell cycle regulation
Published 2025-02-01“…Analysis of differentially expressed genes (DEGs) revealed that these genes are involved in the regulation of post-translational modification, protein turnover, and signal transduction mechanisms. …”
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6734
Using Targeted Virotherapy to Treat a Resistant Ewing Sarcoma Model: From the Bedside to the Bench and Back
Published 2014-01-01“…This study has been designed to implement a translational link between the bedside and the bench, where a specific challenging clinical scenario guided this basic science research. …”
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6735
Variation in Botryosphaeriaceae from Eucalyptus plantations in YunNan Province in southwestern China across a climatic gradient
Published 2020-10-01“…Isolates were identified by comparing DNA sequences of the internal transcribed spacer ribosomal RNA locus (ITS), partial translation elongation factor 1-alpha (tef1), β-tubulin 2 (tub2) and DNA-directed RNA polymerase II subunit (rpb2) genes, and combined with their morphological characteristics. …”
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6736
Robotic Versus Laparoscopic Liver Resection: A Nationwide Propensity Score Matched Analysis
Published 2024-12-01“…It is unknown if this translates to improved patient outcomes. Methods:. Data from the mandatory Dutch Hepatobiliary Audit were used to compare perioperative outcomes of RLR and LLR in 20 centers in the Netherlands (2014–2022). …”
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6737
Biological and psychosocial factors associated with the persistence of pruritus symptoms: protocol for a prospective, exploratory observational study in Germany (individual project...
Published 2022-07-01“…We expect that psychosocial factors relevant to the persistence of symptoms such as fatigue and pain may also show associations to CP.Methods and analysis In this prospective, exploratory observational study situated in Germany, three cohorts of 40 patients each with acute exacerbation of atopic dermatitis and chronic atopic dermatitis and 40 CP patients with unaffected skin will be recruited for a comprehensive translational investigation including pruritus-specific and the shared psychosocial assessments of the RU SOMACROSS. …”
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6738
A single-cell atlas of the Culex tarsalis midgut during West Nile virus infection.
Published 2025-01-01“…ISCs were also found to have a strong transcriptional response to WNV infection; genes involved in ribosome structure and biogenesis, and translation were significantly downregulated in WNV-infected ISC populations. …”
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6739
Antipsychotic prescribing practices and patient, family member and healthcare professional perceptions of antipsychotic prescribing in acute care settings: a scoping review protoco...
Published 2022-06-01“…The results of this scoping review will inform integrated knowledge translation initiatives aimed at in-hospital antipsychotic medication deprescribing.…”
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6740
Social context affects tissue-specific copper distribution and behaviour of threespine stickleback (Gasterosteus aculeatus)
Published 2025-01-01“…The objective of this study was to investigate whether inducing social stress in marine threespine stickleback (Gasterosteus aculeatus) through social isolation during a sublethal water-borne copper (Cu) exposure would affect Cu uptake and whether that would translate to differences in behaviour and biochemical functioning. …”
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