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6641
Protocol for the impact of machine learning-based clinician decision support algorithims in perioperative care (IMAGINATIVE) in Singapore general hospital : a large prospective ran...
Published 2024-12-01“…All patients will sign an informed consent form before recruitment and translators will be made available to non-English-speaking participants. …”
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6642
Gene regulatory patterning codes in early cell fate specification of the C. elegans embryo
Published 2024-01-01“…This classic model however does not translate directly to species that lack a syncytium – such as Caenorhabditis elegans – where cell fate is specified by cell-autonomous cell lineage programs and their inter-signaling. …”
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6643
Health impacts and economic costs of residential fires (RESFIRES study): protocol for a population-based cohort study using linked administrative data
Published 2020-09-01“…The study reference group comprises key stakeholders including Fire and Rescue NSW, policy agencies, health service providers and burns clinicians ensuring wide dissemination of results and translation of data to inform practice and identify areas for targeted prevention. …”
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6644
Normative Values of Brainstem Auditory-Evoked Responses in Sheep
Published 2025-01-01“…However, normative data for BAERs in sheep, which represent an adequate large animal model for translational and basic otological research, are lacking. …”
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6645
High fatigue levels among psychiatric outpatients – the validity of the Danish Patient Reported Outcomes Measurement Information System Fatigue Short-Form (PROMISF-SF)
Published 2025-01-01“…Methods Patients in the Mental Health Service Outpatient Clinics and healthy volunteers were invited to complete a survey, which included the Danish translation of the PROMIS-F-SF, the Chalder Fatigue Scale (CFS-11), and measures of depression and anxiety. …”
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6646
Cross-cultural adaptation: South African Gestational Diabetes Mellitus Knowledge Questionnaire
Published 2025-01-01“…The aim of this study was to translate and cross-culturally adapt and test the preliminary internal consistency and test-retest reliability of the South African English, Afrikaans and isiXhosa versions of the GDM Knowledge Questionnaire (GDMKQ). …”
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6647
What Is Grazing Time? Insights from the Acoustic Signature of Goat Jaw Activity in Wooded Landscapes
Published 2024-12-01“…This has implications for how animal presence should be translated to grazing pressure and for how long animals need to forage to meet their nutritional requirements.…”
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6648
Multilocus phylogenies reveal three new truffle-like taxa and the traces of interspecific hybridization in Octaviania (Boletaceae, Boletales)
Published 2021-06-01“…Here we describe two new species in subgenus Octaviania, O. tenuipes and O. tomentosa, from temperate to subtropical evergreen Fagaceae forests in Japan based on morphological observation and robust multilocus phylogenetic analyses (nrDNA ITS and partial large subunit [LSU], translation elongation factor 1-α gene [TEF1] and the largest subunit of RNA polymerase II gene [RPB1]). …”
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6649
Construction of a potentially functional long noncoding RNA-microRNA-mRNA network in diabetic cardiomyopathy
Published 2024-12-01“…Further experimental validation and clinical studies are warranted to translate these findings into clinical applications.…”
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6650
Enhanced protective effect of selenium-biofortified peptide RYNA(Se)MNDYT compared with its native peptide RYNAMNDYT in lipopolysaccharide-injured murine gut microbiota
Published 2024-11-01“…Furthermore, Se-biofortification in Se-enriched Cordyceps militaris affected the parental proteins of Se-P2 to modulate mitogen-activated protein kinase, GPI anchored protein, and carbohydrate metabolism, translation, folding, sorting and degradation, which may contribute to the bioactivity of Se-P2. …”
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6651
Investigation on Nonlinear Flow Behavior through Rock Rough Fractures Based on Experiments and Proposed 3-Dimensional Numerical Simulation
Published 2020-01-01“…Reservoir sandstones as a case study, four splitting groups of fractures with different roughness were scanned to get the geometric features, and then the seepage experiments were taken to analyze the relationship of the pressure gradient ∇Pand flow rate Q, and the critical Reynolds number(Rec) and wall friction factor (f) were determined to explain the translation of linear seepage to nonlinear seepage condition. …”
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6652
Examining the integration of refugees into the national health system in Uganda: an analysis using the policy triangle framework
Published 2025-01-01“…The findings shed light on the importance of collaboration between stakeholders, mobilization of legal and political frameworks to shape the integration of refugee health services into the national health system, and the importance of ensuring that high-level commitments translate to action and development plans at local levels.…”
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6653
Backtranslation of human RNA biosignatures of tuberculosis disease risk into the preclinical pipeline is condition dependent
Published 2025-01-01“…Human-derived COR signatures offer an opportunity for high-throughput preclinical endpoint criteria of vaccine and drug therapy evaluations.IMPORTANCEUnderstanding the strengths or limitations of back-translating human-derived correlate of risk (COR) RNA signatures into the preclinical pipeline may help streamline down-selection of therapeutic vaccine and drug candidates and better align preclinical models with proposed clinical trial efficacy endpoints.…”
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6654
Targeted CQA analytical control strategy for commercial antibody products: Replacing ion-exchange chromatography methods for charge heterogeneity with multi-attribute monitoring
Published 2024-12-01“…Historically, peptide mapping monitors post-translational modifications (PTMs) of protein products and process intermediates during development. …”
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6655
Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion
Published 2019-01-01“…However, many more cellular processes are affected by pathological processes in C9FTD/ALS, including nucleocytoplasmic transport, RNA processing, normal function of nucleolus, formation of membraneless organelles, translation, ubiquitin proteasome system, Notch signalling pathway, granule transport, and normal function of TAR DNA-binding protein 43 (TDP-43). …”
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6656
MODERN STATE LANGUAGE POLICY
Published 2015-11-01“…The perspective directions of the state language policy in the field of the Russian language and literature are specified and formulated: the analysis of the programs and projects aimed at the development, distribution and support of the Russian language; providing coordination of actions of executive authorities in the presented study; improvement of the Russian language studying quality in schools in accordance with features of the general education in the national republics; professional level improvement of teachers of the Russian language; preservation of national languages of Russia; scientific studying and codification of the modern language, promoting of scientific knowledge of Russian and languages of the people of the Russian Federation; support expansion of the private initiatives connected with preservation and development of Russian in neighboring countries; creation of base for studying of Russian by foreign experts and labor migrants; cooperation with foreign specialists in the Russian philology, translators of the Russian literature and teachers of Russian.…”
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6657
The effects of aerobic exercise and heat stress on the unbound fraction of caffeine
Published 2025-01-01“…In light of the well-established effects of exercise on body temperature and blood pH, we investigated whether an increase in blood temperature and decrease in pH facilitated through passive heating and exercise translated to a change in the fu of caffeine.MethodsTen healthy participants (4 females and 6 males; age: 21.9 ± 2.7 years [means ± SD]) ingested 3 mg/kg of anhydrous caffeine on two separate occasions comprised of a control trial involving 105 min of rest, and an experimental trial involving 10 min of passive heating, followed by 20 min of cycling at 55% V˙O2peak, and then 10 sprint intervals at 90% V˙O2peak. …”
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6658
The process and logical mechanism of agricultural production space contraction in mountainous areas based on actor-network theory:A case study of Lishi Village in Longde County, Ni...
Published 2025-01-01“…[Results] The study found that: (1) The translation of actor networks at different stages, the entry and exit of heterogeneous actors within the networks, and the transformation of the actor networks goals comprehensively contributed to the contraction of agricultural production space through the combined effects of human and non-human actors. (2) During the transformation of the actor network in Lishi Village, the key actor changed from the local government to the young labor force, and the obligatory point of passage (OPP) changed from “returning farmland to forest and grassland” to “developing specialty farming to maximize economic income”. (3) The agricultural production space in Lishi Village has gone through two stages: explicit contraction under the ecological objective and implicit contraction under the economic objective. (4) The contraction of agricultural production space in mountainous areas follows the mechanisms of environmental logic, policy-driven logic, and multi-subject logic. …”
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6659
Insights into semi-continuous synthesis of iron oxide nanoparticles (IONPs) via thermal decomposition of iron oleate
Published 2025-01-01“…Our work advances the understanding of of synthesis-property relationships of IONPs by demonstrating the translation of established synthesis protocols into more efficient and scalable processes through which it provides insights for developing and optimizing future production protocols for various applications. …”
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6660
Airborne lidar intensity correction for mapping snow cover extent and effective grain size in mountainous terrain
Published 2024-12-01“…The lidar-derived grain size retrievals had a MAE of 32 µm compared to those from field spectroscopy, which translated to a 1% error in snow albedo. We found high incidence angles yielded an overcorrection in intensity that introduced a high bias in the grain size distribution and, therefore, suggest using an incidence angle threshold (40°). …”
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