Advances in therapies using mesenchymal stem cells and their exosomes for treatment of peripheral nerve injury: state of the art and future perspectives by Fatima Aldali, Chunchu Deng, Mingbo Nie, Hong Chen

“…A comprehensive review of the latest preclinical experiments and clinical trials is essential for deep understanding of therapeutic strategies and for facilitating clinical translation. This review initially explores current investigations of mesenchymal stem cells and mesenchymal stem cell–derived exosomes in peripheral nerve injury, exploring the underlying mechanisms. …”
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Bicarbonate Within: A Hidden Modulator of Antibiotic Susceptibility by Selvi C. Ersoy, Warren E. Rose, Richard A. Proctor

“…This “NaHCO₃-responsive” phenotype is widespread among US MRSA USA300/CC8 bloodstream and skin and soft tissue infection isolates. Translationally, β-lactam therapy has proven effective against NaHCO₃-responsive MRSA in both ex vivo simulated endocarditis vegetation (SEV) and in vivo rabbit infective endocarditis (IE) models. …”
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Chat GPT 4o vs residents: French language evaluation in ophthalmology by Leah Attal, Elad Shvartz, Nakhoul Nakhoul, Daniel Bahir

“…Therefore, this study's aim is to evaluate ChatGPT 4o's accuracy to MCQs from the national ophthalmology residency examination in French language, compared to residents and other leading AI chatbots Methods: A set of 600 questions from the national ophthalmology examination was translated into French and submitted to ChatGPT 4o, ChatGPT 4, and Gemini Advanced. …”
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Barriers and facilitators to conducting human subjects research at a safety net institution from the perspective of researchers. by Sarah J Barnes, Yewon Na, Mari-Lynn Drainoni, Benjamin A Linas, Nicholas A Bosch, Autumn L Tamlyn

“…<h4>Results</h4>We completed 28 interviews and identified five themes: (1) compared to non-safety net systems, safety-net systems were perceived to require additional resources and funding to achieve comparable research recruitment and retention; (2) language barriers and translational processes are burdensome for researchers; (3) interactions between research staff and patients impact trust; (4) social determinants of health specific to safety-net populations are a barrier to participation; (5) competing priorities between clinical staff and researchers exist.…”
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Community responses to a novel house design: A qualitative study of "Star Homes" in Mtwara, southeastern Tanzania. by Salum Mshamu, Judith Meta, Bipin Adhikari, Salma Halifa, Arnold Mmbando, Hannah Sloan Wood, Otis Sloan Wood, Thomas Chevalier Bøjstrup, Nicholas P J Day, Steven W Lindsay, Jakob Knudsen, Jacqueline Deen, Lorenz von Seidlein, Christopher Pell

“…Interviews were conducted in Swahili, transcribed, and translated into English for thematic analysis.<h4>Results</h4>Star Homes residents appreciated several aspects of the Star Homes, including overall comfort, access to water and electricity, and clean toilets. …”
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Effect of Fungal and Fungal-Bacterial Tempe-Type Fermentation on the Bioactive Potential of Grass Pea Seeds and Flaxseed Oil Cake Mix by Bożena Stodolak, Maja Grabacka, Anna Starzyńska-Janiszewska, Robert Duliński

“…However, the enrichment of the products with antioxidants resulting from solid-state fermentation did not simply translate into an improvement in antioxidant potential after digestion. …”
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Carnitine palmitoyltransferase 1C promotes EMT-associated cisplatin resistance in non-small cell lung cancer cells by Renjie Chen, Jiahui Wang, Shuoyu Huang, Xuefeng Hu, Xinran He, Tiange Zhang, Yunhan Hu, Huijun Wei, Sihui Nian, Yushu Huang, Zhihao Wu

“…Moreover, CPT1C was shown to be regulated at the post-translational level and an E3-ubiquitin ligase, NEDD4L, was shown to be a major regulator of CPT1C stability and activity. …”
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Noncontact Palm Vein ROI Extraction Based on Improved Lightweight HRnet in Complex Backgrounds by Fen Dai, Ziyang Wang, Xiangqun Zou, Rongwen Zhang, Xiaoling Deng

“…A noncontact palm vein ROI extraction algorithm based on the improved HRnet for keypoints localization was proposed for dealing with hand gesture irregularities, translation, scaling, and rotation in complex backgrounds. …”
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Development and implementation of an electronic health record system for use in humanitarian emergencies, disaster response, and conflict zones. by Sarah D Draugelis, Erik C Brown, Donald A Donahue, Justin Hickman, Sean G Smith, Philip Sutherland, George A Yendewa, Amir M Mohareb

“…Ongoing and future work in adapting electronic health records to international humanitarian response will emphasize data security, patient privacy, equity, and the rapid translation of electronic health data to improve population health. …”
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A rare case of double pituitary prolactinomas: the diagnostic application of intraoperative ultrasonography and DNA methylation markers by Jared C. Reese, Thomas M. Zervos, Jack Rock, Abeer Tabbarah, Houtan Noushmehr, Grayson Herrgott, Ana Valeria Castro

“…This case illustrates the translational use of methylation-based liquid biopsy methodologies in detecting and monitoring PTs through the detection of tumor-specific markers in blood specimens. …”
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Unraveling the pathogenesis of Barrett’s esophagus and esophageal adenocarcinoma: the “omics” era by Alberto Barchi, Giuseppe Dell’Anna, Giuseppe Dell’Anna, Luca Massimino, Luca Massimino, Francesco Vito Mandarino, Edoardo Vespa, Edi Viale, Sandro Passaretti, Vito Annese, Vito Annese, Alberto Malesci, Alberto Malesci, Silvio Danese, Silvio Danese, Federica Ungaro

“…The implementation of transcriptomic and proteomic analysis, even at the single-cell level, has widened the horizons, complementing the genomic alterations with their transcriptional and translational bond. Increasing interest has been gathered around small circulating genetic traces (circulating-free DNA and micro-RNAs) with a potential role as blood biomarkers. …”
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Adaptation of an exercise intervention for pregnant women to community-based delivery: a study protocol by Aline Andres, Elisabet Børsheim, Taren Swindle, Audrey Martinez

“…Studies need to determine feasible ways to translate clinical interventions to community settings by engaging pregnant women in widely accessible locations to ensure benefits to more women. …”
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Adolescent and adult mice use both incremental reinforcement learning and short term memory when learning concurrent stimulus-action associations. by Juliana Chase, Liyu Xia, Lung-Hao Tai, Wan Chen Lin, Anne G E Collins, Linda Wilbrecht

“…In a version of the human RL+WM task translated for rodents, mice were required to associate odor stimuli (from a set of 2 or 4 odors) with a left or right port to receive reward. …”
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Enhanced detection of circulating tumor cells using a MUC1 promoter-driven recombinant adenovirus by Cheng Wang, Huihui Gu, Jia Cai, Chuandong Zhu, Qin Zheng, Hanfeng Xu, Lixue Wang, Yuan Wan

“…Moreover, rAdF35-MUC1 demonstrated reduced incidence of false positives in healthy PBMCs compared to rAdF35-hTERT.ConclusionIn brief, rAdF35-MUC1 emerges as a potent tool for the sensitive and specific identification of CTCs derived from breast cancer patients, holding clinical translation potential for advancing cancer (early) diagnosis, treatment monitoring, and prognosis.…”
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Islamic boarding schools and human rights enforcement transmission of cultural values for disabilities by Suwarno Suwarno, Uswatun Chasanah

“…These three cultural transmissions are carried out in the educational process at Islamic boarding schools for 24 hours through theological understanding and translating at the practical level in the form of self-accustoming, exemplary, formal and informal learning, and life skills activities for students in Islamic boarding schools.…”
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TEC-mediated tRF-31R9J regulates histone lactylation and acetylation by HDAC1 to suppress hepatocyte ferroptosis and improve non-alcoholic steatohepatitis by Juanjuan Zhu, Xian Wu, Mao Mu, Quan Zhang, Xueke Zhao

“…Recent discoveries have revealed that histone lactylation and acetylation play a crucial role in connecting cellular metabolism and epigenetic regulation through post-translational modification of histones. However, it is unclear whether TEC improves NASH by regulating histone lactylation, acetylation and hepatocyte ferroptosis through tRFs. …”
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Examining the Gm18 and mG Modification Positions in tRNA Sequences by Mayavan Subramanian, Thangavelu Srinivasan, Dorairaj Sudarsanam

“…The tRNA structure contains conserved modifications that are responsible for its stability and are involved in the initiation and accuracy of the translation process. tRNA modification enzymes are prevalent in bacteria, archaea, and eukaryotes. tRNA Gm18 methyltransferase (TrmH) and tRNA m1G37 methyltransferase (TrmD) are prevalent and essential enzymes in bacterial populations. …”
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Tiny clue reveals the general trend: a bibliometric and visualized analysis of renal microcirculation by Bing Wang, Mengting Xu, Sunjing Fu, Yingyu Wang, Hao Ling, Yuan Li, Bingwei Li, Xueting Liu, Qin Ouyang, Xiaoyan Zhang, Ailing Li, Xu Zhang, Mingming Liu

“…While the trends discerned from the literature emerging opportunities in diagnostic innovation, renal microcirculation research, and precision medicine interventions, their translation to clinical practice is anticipated to be a deliberate process.…”
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Synergistic Antibacterial Action of Norfloxacin-Encapsulated G4 Hydrogels: The Role of Boronic Acid and Cyclodextrin by Monica-Cornelia Sardaru, Irina Rosca, Simona Morariu, Elena-Laura Ursu, Alexandru Rotaru

“…Nevertheless, further in vivo studies and long-term stability assessments are needed to fully establish clinical relevance, safety, and scalability before these systems can be translated into routine healthcare applications.…”
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Where are Our Educators? by Елізабет Тюнс, Зоя Рібейро Престес

“…For exempl, a confessed Manichaeism was present in the initial vision of Max Fisher – a reporter for the New York Times – regarding social networks and digital platforms, as he himself declared in the book The Chaos Machine (Fisher, 2023), which he published in 2022, translated into Portuguese, in 2023. Like many, at the beginning, he assumed that the dangers of social media came mainly from inappropriate use by malicious people – propagandists, spies, spreaders of fake news – and that, at worst, the platforms were a passive pipeline where the existing problems in society ran. …”
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