Insights from the single-cell level: lineage trajectory and somatic-germline interactions during spermatogenesis in dwarf surfclam Mulinia lateralis by Yajuan Li, Huilan Wei, Xiaoting Dai, Lijing Zhang, Liangjie Liu, Xiaomei Chen, Tian Liu, Ya Shu, Yaxin Yang, Shi Wang, Zhenmin Bao, Lingling Zhang

“…Pseudotime analysis indicates that gene expression, translation, ATP metabolic process, and microtubule-based process are involved in the transition of germ cell types. …”
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On the Work of Cartan and Münzner on Isoparametric Hypersurfaces by Thomas E. Cecil, Patrick J. Ryan

“…These papers of Cartan and Münzner have been the foundation of the extensive field of isoparametric hypersurfaces, and they have all been recently translated into English by T. Cecil. The paper concludes with a brief survey of the recently completed classification of isoparametric hypersurfaces in spheres.…”
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Renouveler les connaissances sur les risques liés aux sports de montagne : l’exemple d’un laboratoire collaboratif d’accidentologie by Maud Vanpoulle, Bastien Soulé, Eric Boutroy, Brice Lefèvre

“…At its source, the SERAC project has two complementary but also divergent aims: that of collaborative action research to support social innovation, and the production of contextualized knowledge that can ideally be translated into accident prevention recommendations and a better understanding of risky alpine practices.…”
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Salubrinal Regulates the Apoptosis of Adrenocortical Carcinoma Cells via the PERK/eIF2α/ATF4 Signaling Pathway by Lili Wu, Chunfeng Liang, Xuemei Huang, Xiujun Deng, Jiming Jiang, Zuojie Luo

“…In this study, we aimed to determine whether salubrinal (Sal), a selective activator of eukaryotic translation initiation factor 2 (eIF2α), can induce apoptosis of human adrenocortical carcinoma (ACC) cell via activating the PERK/eIF2α/ATF4 signaling pathway, and the potential mechanisms of this action were explored. …”
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Continuous Sign Language Recognition With Multi-Scale Spatial-Temporal Feature Enhancement by Zhen Wang, Dongyuan Li, Renhe Jiang, Manabu Okumura

“…Continuous Sign Language Recognition (CSLR) seeks to interpret the gestures used by people who are hard of hearing-mute individuals and translate them into natural language, thereby enhancing communication and interaction. …”
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Phase I clinical trial testing the dose escalation and expansion of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin administration (PITHAC) for the management of pleural c... by Louis-Emmanuel Chriqui, Etienne Abdelnour-Berchtold, Edoardo Zanfrini, Severine Devesa-Perez, Michel Gonzalez, Thorsten Krueger, Kim Ellefsen, Alice Destaillats, David Bonnet, Martin Hübner, Hasna Bouchaab, Michal Bassani-Sternberg, Solange Peters, Sabrina Cavin, Jean Y Perentes

“…The secondary and translational endpoints are adverse events and the immune response directed against cancer following PITHAC. …”
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Ticam2 ablation facilitates monocyte exhaustion recovery after sepsis by Blake A. Caldwell, Susanti Ie, Amy Lucas, Liwu Li

“…To determine the impact of TICAM2 ablation on innate epigenetic memory in sepsis, we measured genome-wide DNA methylation in bone marrow monocytes and found that Ticam2 -/- cells exhibit a unique profile of altered methylation at CEBPE binding sites and regulatory features for key immune genes such as Dmkn and Btg1. Bearing human translational relevance, a case study of time course blood samples collected from a sepsis patient presenting with SIRS and a positive qSOFA revealed a similar effect in human monocytes, which steadily transition into an exhausted memory characterized by a CD38high; CX3CR1low; HLA-DRlow state within four days of hospital admittance. …”
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A Beam of Light on the Dark Side of the Moon: A Critical Review on the Book Women in Ancient Persia by Ehsan Ahmadinya

“…This article reviews and criticizes this book along with one of its Persian translations.…”
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Adverse Events of Antiepileptic Drugs Using Indonesian Version of Liverpool Adverse Events Profile by Astri Budikayanti, Lubna Muhammad Qadri, Zakiah Syeban, Luh Ari Indrawati, Fitri Octaviana

“…The questionnaire was translated from English into Indonesian version. The validity and reliability were tested using Spearman correlation and Cronbach’s alpha measurement. …”
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A High-Throughput Method as a Diagnostic Tool for HIV Detection in Patient-Specific Induced Pluripotent Stem Cells Generated by Different Reprogramming Methods by Daniela Hübscher, Sabine Rebs, Luis Haupt, Thomas Borchert, Celina Isabell Guessoum, Franziska Treu, Steffen Köhne, Andreas Maus, Mario Hambrecht, Samuel Sossalla, Ralf Dressel, Angela Uy, Mark Jakob, Gerd Hasenfuss, Katrin Streckfuss-Bömeke

“…Induced pluripotent stem cells (iPSCs) provide a unique opportunity for generation of patient-specific cells for use in translational purposes. We aimed to compare iPSCs generated by different reprogramming methods regarding their reprogramming efficiency, pluripotency capacity, and the possibility to use high-throughput PCR-based methods for detection of human pathogenic viruses. iPSCs from skin fibroblasts (FB), peripheral blood mononuclear cells (PBMCs), or mesenchymal stem cells (MSCs) were generated by using three different reprogramming systems including chromosomal integrating and nonintegrating methods. …”
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Double diffusive MHD stagnation point flow of second grade fluid in non-Darcy porous media under radiation effects by Walid Aich, Amir Abbas, Adebowale Martins Obalalu, Walid Hassen, Lotfi Ben Said, Rejab Hajlaoui, Lioua Kolsi

“…Mathematical models are developed for the current situation and translated into a set of ordinary differential equations that are solved using MATLAB’s bvp4c. …”
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CAN CLEAR ALIGNERS THERAPY ACHIEVE MAXILLARY EXPANSION IN PATIENTS WITH TRANSVERSE MALOCCLUSIONS? A SYSTEMATIC REVIEW by Ibraheem Bamaga

“…The efficacy of expansion with clear aligners was more prominent in the canine and premolar area, with the expansion mainly achieved with tipping movements rather than bodily translation movement. The planning software overpredicted the dental movements compared to what was achieved. …”
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Lower urinary dysfunction as a long-term effect of childhood vincristine treatment, with potential influences by sex and dose by Nao Iguchi, Ali Teimouri, Duncan T. Wilcox, Anna P. Malykhina, Nicholas G. Cost

“…Our initial clinical and translational investigations suggest a sex-specific influence of childhood VCR exposure on LUT function. …”
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Exosomes: Key Messengers Mediating the Interaction Between Tumor Cells and CD8+ T Cells in the Tumor Microenvironment by Li Y, Yang Q, Li D, Li W, Men W

“…Furthermore, it summarizes the potential for clinical treatment in this realm when integrated with existing immunotherapy methods—particularly exploring the feasibility of clinical translation alongside engineering materials science techniques.Keywords: CD8+T, TME, exosome, EVs…”
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IONPs-induced neurotoxicity via cascade of neuro-oxidative stress, parthanatos-mediated cell death, neuro-inflammation and neurodegenerative changes: Ameliorating effect of rosemar... by Arwa A. Elsheikh, Noha Ali Abd-Almotaleb, Mona Mostafa Ahmed, Eman El-Sayed Khayal

“…Consequently, the current data provide evidence that RO supplementation during IONP administration holds promise to minimize potential health risks, which should be corroborated by translational studies.…”
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Development of chimeric Nanobody-Granzyme B functionalized ferritin nanoparticles for precise tumor therapy by Baijin Xia, Huolun Feng, Xinmiao Jiang, Jialing Guo, Keming Lin, Wenxing Zhang, Fan Xing, Lixue Cao, Yong Li, Hui Zhang, Xu Zhang, Wenyu Li, Fei Yu

“…Our findings highlight the potential of engineered nanoparticles as effective and targeted therapeutic agents across various tumor types, offering promising prospects for clinical translation in cancer treatment.…”
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rule4ml: an open-source tool for resource utilization and latency estimation for ML models on FPGA by Mohammad Mehdi Rahimifar, Hamza Ezzaoui Rahali, Audrey C Therrien

“…We leverage HLS4ML, a tool-flow that helps translate NNs into high-level synthesis (HLS) code, to synthesize a diverse dataset of NN architectures and train resource utilization and inference latency predictors. …”
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Evolution of the RNA alternative decay cis element into a high-affinity target for the immunomodulatory protein Roquin by Jan-Niklas Tants, Katharina Friedrich, Jasmina Neumann, Andreas Schlundt

“…RNA cis elements play pivotal roles in regulatory processes, e.g. in transcriptional and translational regulation. Two stem-looped cis elements, the constitutive and alternative decay elements (CDE and ADE, respectively) are shape-specifically recognized in mRNA 3’ untranslated regions (UTRs) by the immune-regulatory protein Roquin. …”
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Fluorescent Nanoparticle Imaging Allows Noninvasive Evaluation of Immune Cell Modulation in Esophageal Dysplasia by Peiman Habibollahi, Todd Waldron, Pedram Heidari, Hoon Sung Cho, David Alcantara, Lee Josephson, Timothy C. Wang, Anil K. Rustgi, Umar Mahmood

“…Our observations suggest that this translatable technology may be used for the early detection of dysplastic changes and the serial assessment of immunomodulatory therapy and to visualize changes in MDSCs in the esophageal tumor microenvironment.…”
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Non3 is an essential Drosophila gene required for proper nucleolus assembly by E. N. Andreyeva, A. A. Ogienko, A. A. Yushkova, J. V. Popova, G. A. Pavlova, E. N. Kozhevnikova, A. V. Ivankin, M. Gatti, A. V. Pindyurin

“…We also demonstrate that the Non3 protein localizes to the nucleolus of larval brain cells and it is required for proper nucleolar localization of Fibrillarin, a protein important for post-translational modification and processing of rRNAs. In summary, we generated a number of genetic and biochemical tools that were exploited for an initial characterization of Non3, and will be instrumental for future functional studies on this gene and its protein product.…”
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