Deep Learning for Identification and Characterization of Ca ii Absorption Lines: A Multitask Convolutional Neural Network Approach by Yang Liu, Jie Li, Linqing Gao, Haotong Zhang, Zhenghua Xu, Yu Wang, Wenbin Lin

“…In addition, with our numerous optimizations, our method can directly search for nonnormalized data, still achieving an accuracy of 98.6%. This translates to a dramatic reduction in manual inspection workload, paving the way for efficient and automated Ca ii absorber identification. …”
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The Roles of MicroRNAs in the Regulation of Rice–Pathogen Interactions by Yanfeng Jia, Kai Wei, Jiawang Qin, Wenxue Zhai, Quanlin Li, Yalan Li

“…MiRNAs can modulate target gene expression at the post-transcriptional level through mRNA cleavage and/or translational inhibition. In rare instances, they also influence gene expression at the transcriptional level through DNA methylation. …”
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Health care provider's perceived factors for the increased practice of caesarean delivery in North West Amhara referral hospitals, Ethiopia, 2022: a qualitative study by Mulat Ayele, Marta Berta, Amare Zewudie, Eyob Shitie Lake, Gizachew Yilak, Befkad Derese Tilahun, Mastewal Belayneh Aklil

“…Transcribed interviews were translated coded and finally thematic analyses were employed using Open Code 4.0 software.ResultsHealthcare providers observed a significant increase in the frequency of caesarean deliveries. …”
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Slaying axion-like particles via gravitational waves and primordial black holes from supercooled phase transition by Angela Conaci, Luigi Delle Rose, P. S. Bhupal Dev, Anish Ghoshal

“…Similarly, depending on the ALP couplings to other Standard Model particles, the ALP constraints on f a can be translated into a lower bound on the PBH mass scale. …”
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Dioscin pretreatment ameliorates ferroptosis in cardiomyocytes after myocardial infarction via inhibiting endoplasmic reticulum stress by Chang Wu, Xueping Shen, Pan Lou, Dongyan Song

“…Further investigations into the precise molecular mechanisms and clinical translation of Dioscin’s cardioprotective effects are warranted, offering a potential avenue for novel therapeutic interventions in MI-related cardiac complications. …”
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RUBY® – a tetravalent (2+2) bispecific antibody format with excellent functionality and IgG-like stability, pharmacology and developability properties by Barnabas Nyesiga, Mattias Levin, Anna Säll, Anna Rosén, Kim Jansson, Sara Fritzell, Karin Hägerbrand, Dietmar Weilguny, Laura von Schantz

“…Also, retained interaction with FcRn is demonstrated to translate into a pharmacokinetic profile in mice and non-human primates that is comparable to mAb controls. …”
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Bionic nanovesicles sequentially treat flaps with different durations of ischemia by thrombolysis and prevention of ischemia-reperfusion injury by Linzhong Yang, Yuanchen Liu, Cheng Tao, Zichen Cao, Shilin Guo, Zheng Wei, Yanyi Wang, Tao Liu, Lin Chen, Ke Xiong, Xingyu Luo, Jianchuan Ran, Wei Han

“…Specifically, we have successfully constructed a clinical-grade bionic vesicle, UK-PBNZ@PM, a system that cleverly incorporates drug components that have been widely used in clinical applications, thereby demonstrating a high degree of clinical translational potential. Prussian blue nano-enzymes (PBNZ) are the core component and demonstrate remarkable efficacy against ischemia-reperfusion injury due to their excellent biocompatibility, robust reactive oxygen species (ROS) scavenging capacity and anti-inflammatory properties. …”
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Enhancing Cluster Accuracy in Diabetes Multimorbidity With Dirichlet Process Mixture Models by Francis John Kita, Srinivasa Rao Gaddes, Peter Josephat Kirigiti

“…Results show that DPMM consistently outperforms traditional methods in clustering high-dimensional and imbalanced datasets, offering significant translational potential for guiding tailored healthcare strategies for complex chronic diseases and optimizing healthcare resource allocation.…”
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Mitochondria-Targeted Biomaterials-Regulating Macrophage Polarization Opens New Perspectives for Disease Treatment by Tian Z, Wang X, Chen S, Guo Z, Di J, Xiang C

“…Finally, the prospects and challenges of the use of these biomaterials in disease modulation have been explored, emphasizing their potential to be translated to the clinic. It is anticipated that this review will serve as a valuable resource for materials scientists and clinicians in the development of next-generation mitochondria-targeted biomaterials.Keywords: macrophages, polarization, biomaterials, mitochondria…”
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Building Responsive Intersectoral Initiatives for Newcomers in Toronto: Learning from Service Providers’ Experiences in the Context of COVID-19 by Carly Jackson, Shinjini Mondal, Erica Di Ruggiero, Lara Gautier

“…Conclusions: The findings demonstrate that intersectoral initiatives can be implemented to develop a responsive service for marginalized populations; however, their translation beyond pandemic settings would require institutional mechanisms to bring policy shifts to provide a bottom-up collaborative approach.…”
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QUANTIFICATION CONTRASTS OF LEXICAL MICROSYSTEMS WITH SYNONYMS SЪVEDETELЬ – POSLUKHЪ (A WITNESS) AND THEIR DERIVATIVES IN THE OLD EAST SLAVIC WRITTEN SOURCES (BASED ON MANUSCRIPT... by Oleg F. Zholobov

“…In church-associated written sources, the pair sъvědětelь – posluchъ, together with their derivatives, correlate with the Cyril-and-Methodius and Preslav translation traditions. In the church written tradition, the ratio of lexemes in the corresponding lexical series is expressed by contrasting quantitative formulas that reflect the text-critical history, genre-stylistic nature, and discursive dominants of the texts. …”
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Evaluation of antibiotic treatment initiation and duration practices in primary care. Cross-sectional study in two French multi-professional health centers. by Simon Ferme, Emmanuel Piednoir, Marianne Delestre, Elise Fiaux, Johann Masik, Renaud Verdon, Pascal Thibon

“…For nasopharyngitis, the high frequency of this condition translates into potentially large prescribing volumes on a collective scale. …”
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Exhausting the (Human) Problem by Annalaura Alifuoco

“…Their plastic techniques translate into corporeal masses of alternative enfleshments that resist both completion and categorization. …”
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Protective effects of wogonin in the treatment of central nervous system and degenerative diseases by Qingan Fu, Qingyun Yu, Hongdan Luo, Zhekang Liu, Xiaowei Ma, Huijian Wang, Zhijuan Cheng

“…Future researchers need to further explore the long-term efficacy and safety of wogonin in clinical trials and translate it for early application in the clinical treatment of true CNS disorders.…”
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Analyzing and Visualizing Uncertain Knowledge: The Use of TEI Annotations in the PROVIDEDH Open Science Platform by Michał Kozak, Alejandro Rodríguez, Alejandro Benito-Santos, Roberto Therón, Michelle Doran, Amelie Dorn, Jennifer Edmond, Cezary Mazurek, Eveline Wandl-Vogt

“…Then we describe use cases of annotations available on the platform, and how they translate into TEI annotations. Creating and interpreting annotations with and without uncertainty should now be easier, especially for researchers who do not know TEI markup.…”
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Analysis of the role of acetylation in Giardia lamblia and the giardicidal potential of garcinol by Rocío G. Patolsky, Jerónimo Laiolo, Jerónimo Laiolo, Luciano Díaz-Pérez, Gabriel Luna Pizarro, Gonzalo F. Mayol, María C. Touz, Constanza Feliziani, Andrea S. Rópolo

“…IntroductionPost-translational modifications of proteins provide cellular physiology with a broad range of adaptability to the external environment flexibly and rapidly. …”
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Harnessing the anticancer potential of Piper nigrum: a synergistic approach to chemotherapy enhancement and reduced side effects by Hesti Lina Wiraswati, Ilma Fauziah Ma’ruf, Nur Akmalia Hidayati, Julia Ramadhanti, Daniela Calina, Javad Sharifi-Rad

“…Future research directions are discussed to address current limitations and facilitate clinical translation.…”
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The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function. by Catherine B Reynolds, Jenny E Emerson, Lucia de la Riva, Robert P Fagan, Neil F Fairweather

“…Using targeted gene knock-out, we show that a single site-specific recombinase RecV is required for CwpV phase variation. CwpV is post-translationally cleaved at a conserved site leading to formation of a complex of cleavage products. …”
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Action against birth defects: if not now, when? by Kathleen Strong, Judith Robb-McCord, Salimah Walani, Cecilia Mellado, Lorenzo D. Botto, Guillermo Lay-Son, Theresa Diaz, Tahmina Banu, Kokila Lakhoo, Anshu Banerjee

“…More births and better survival without effective prevention and treatment for birth defects translates into more mortality and disability from birth defects. …”
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Argument by Numbers: the Normative Impact of Statistical Legal Tech by L. Diver, P. McBride

“…We conclude that reliance on the vigilance of individual lawyers is insufficient to guard against the potentially harmful effects of such systems, given their inscrutability, and suggest that the onus is on the providers of legal technologies to demonstrate the legitimacy of their systems according to the standards inherent in the legal system.The translation and publication of this article is based on the CC BY Attribution-NonCommercial 4.0 International license, under which this article was published in English at https://osf.io/preprints/socarxiv/ts259/. …”
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