Beyond Tumors: The Pivotal Role of TRIM Proteins in Chronic Non-Tumor Lung Diseases by Huang X, Yu W, Wei A, Wang X, Chen S

“…We highlight their potential as biomarkers and therapeutic targets, offering promising avenues for drug development in these debilitating respiratory disorders. However, the translation of these findings into clinical applications faces significant challenges. …”
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Daring to Be Different: The First-Person HIV-Positive Narrator in Two South African Novels by Lizzy Attree

“…Eben Venter’s Afrikaans novel Ek Stamel, Ek Sterwe (1996) which was translated into English by Luke Stubbs as My Beautiful Death (2004), and which has – significantly – received little critical review in English as an HIV narrative, tells the story of a white South African man, Konstant, in the Australian diaspora who eventually succumbs to AIDS. …”
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An original method of direct calculation for the identification of the last hinge and the definition of the deformative state at collapse by Roberto Maria De Salvo

“…If, for each hinge, the product between the plastic moment and the correspondent algebraic sum is made, this product has to be surely positive, due to the verses concordance. This can be translated in k+1 inequalities, with each one furnishing a lower limit for the parameter from which the articulated motion depends. …”
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CompàreGenome: a command-line tool for genomic diversity estimation in prokaryotes and eukaryotes by Gabriele Moro, Rossano Atzeni, Ali Al-Subhi, Maria Giovanna Marche

“…Conclusion CompàreGenome empowers users to explore genomic differences among organisms, translating technical outputs from various tools into actionable insights for biologists. …”
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Exploring Customary Law: Perspectives of Hazairin and Cornelis Van Vollenhoven and its Relevance to the Future of Islamic Law in Indonesia by Ilham Tohari, Siti Rohmah, Ahmad Qiram As-Suvi

“…The primary sources for this research are the original works of Hazairin (Tujuh Serangkai tentang Hukum dan Hazairin, Hukum Kewarisan Bilateral Menurut al-Qur’an dan Hadith) and Van Vollenhoven (Het Adatrecht Van Nederlandsch-Indie and its translated version, Van Vollenhoven on Indonesian Adat Law). …”
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Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics by Naureen Rashid, Zhijian Hu, Asha Jacob, Ping Wang

“…In addition, we emphasize on the challenges to the translational phase and caution that the therapy should allow the immune system to continue to function well against secondary infections during hospitalization.…”
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The present study answers the research question: A corpus-based analysis of collocate directionality in academic English writing by Abdulaziz B. Sanosi

“…The study used a one-million-token corpus compiled of research articles written by Arab scholars in the field of Applied linguistics, literature, and translation. It analyzed the corpus using two software: AntConc and #LancsBox. …”
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Protein Ubiquitylation in Pancreatic Cancer by Thomas Bonacci, Julie Roignot, Philippe Soubeyran

“…Whereas it has been known for more than 3 decades now, ubiquitylation is a post-translational modification of protein that only recently emerged as a major regulator of many biological functions, dependent and independent on the proteasome, whose failure is involved in many human diseases, including cancer. …”
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The role of ferroptosis in colorectal cancer and its potential synergy with immunotherapy by Wenhua Xia, Wenhua Xia, Yuanhao Lv, Yuanhao Lv, Yan Zou, Zhanting Kang, Zhaoyi Li, Jiaqi Tian, Hongyan Zhou, Wei Su, Wei Su, Jiateng Zhong, Jiateng Zhong, Jiateng Zhong, Jiateng Zhong

“…In summary, ferroptosis offers a promising strategy to overcome CRC therapy resistance and enhance immunotherapy efficacy, warranting further investigation and translational application.…”
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Stakeholder perspectives to inform the implementation of a community health worker-delivered home management of hypertension intervention in Zimbabwe by Paddington Tinashe Mundagowa, Malvin Musariri, Pamela Magande, Tendai Hlabangana, Linda Jane Mukwambo, Pemberai Zambezi, Priscillah Muchemwa-Munasirei, Fadzai Mukora-Mutseyekwa

“…Objective Implementing evidence-based innovations often fails to translate into meaningful outcomes in practice due to dynamic real-world contextual factors. …”
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Social technology and rescue of native seeds in the Venezuelan Andes Páramo by Iraima Lugo Montilla, Carla Ladeira Pimentel Águas

“…The study underscores the importance of border relations and cultural translation between different knowledge systems in recovering and conserving native potato seeds. …”
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Development of a broad-spectrum epitope-based vaccine against Streptococcus pneumoniae. by Md Nahian, Muhammad Shahab, Md Rasel Khan, Shopnil Akash, Tanjina Akhtar Banu, Murshed Hasan Sarkar, Barna Goswami, Sanjana Fatema Chowdhury, Mohammad Ariful Islam, Ahmed Abu Rus'd, Shamima Begum, Ahashan Habib, Aftab Ali Shaikh, Jonas Ivan Nobre Oliveira, Shahina Akter

“…GenScript server confirmed the high efficiency of cloning for the construct and in-silico cloning into the pET28a (+) vector using SnapGene, demonstrating successful translation of the epitope region. Immunological responses were shown to be enhanced by the C-IMMSIM server. …”
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What impact has the NIHR Academic Clinical Fellowship (ACF) scheme had on clinical academic careers in England over the last 10 years? A retrospective study by James Neilson, David Jones, Sally Clough, James Fenton, Helen Harris-Joseph, Leesa Rayton, Caroline Magee, Lisa Ann Cotterill

“…Previous ACFs continue to show positive career progression, predominantly in translational and clinical research. The knowledge acquired during the ACF continues to be useful in subsequent roles and trainees would recommend the scheme to others.Conclusions The NIHR ACF scheme is successful as part of an integrated training pathway in developing careers in academic medicine and dentistry.…”
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MoS₂–Plasmonic Hybrid Platforms: Next-Generation Tools for Biological Applications by Nayra A. M. Moussa, Seungah Lee, Seong Ho Kang

“…Despite the promising advancements of MoS₂–plasmonic hybrids, translating these platforms into clinical practice requires overcoming considerable challenges, such as synthesis reproducibility, toxicity, stability in physiological conditions, targeted delivery, and scalable manufacturing. …”
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Advancing precision cancer immunotherapy drug development, administration, and response prediction with AI-enabled Raman spectroscopy by Jay Chadokiya, Kai Chang, Saurabh Sharma, Jack Hu, Jennie R. Lill, Jennifer Dionne, Jennifer Dionne, Jennifer Dionne, Amanda Kirane

“…Lastly, we highlight the translational potential of Raman for its integration in clinical practice for safe and precise patient-centric immunotherapy.…”
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Advances, challenges and future applications of liver organoids in experimental regenerative medicine by Da Gong, Jiaye Mo, Jiaye Mo, Mei Zhai, Fulin Zhou, Guocai Wang, Shaohua Ma, Xiaoyong Dai, Xiaoyong Dai, Xuesong Deng

“…However, a robust model and carrier that closely resemble human physiology are still lacking for translating these theories into practice. The potential for liver regeneration has been a central focus of ongoing research. …”
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Romanian validation study of the Boston questionare in patients with carpal tunnel syndrome by Lenuța Bîrsanu, Roxana Covali, Emanuel Matei Roman, Ioan Alexandru Chirap-Mitulschi, Alin Ciubotaru, Mihaela-Dana Turliuc

“…We conducted a two-parts study: the first part involved the translation and cross-cultural adaptation of the The Boston Carpal Tunnel Questionnaire -Romanian version, while the second part was a prospective cohort clinical study that was designed to psychometrically validate the The Boston Carpal Tunnel Questionnaire. …”
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Decoding the m6A epitranscriptomic landscape for biotechnological applications using a direct RNA sequencing approach by Chuwei Liu, Heng Liang, Arabella H. Wan, Min Xiao, Lei Sun, Yiling Yu, Shijia Yan, Yuan Deng, Ruonian Liu, Juan Fang, Zhi Wang, Weiling He, Guohui Wan

“…Abstract Epitranscriptomic modifications, particularly N6-methyladenosine (m6A), are crucial regulators of gene expression, influencing processes such as RNA stability, splicing, and translation. Traditional computational methods for detecting m6A from Nanopore direct RNA sequencing (DRS) data are constrained by their reliance on experimentally validated labels, often resulting in the underestimation of modification sites. …”
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Characterization of lysine acetyltransferase and deacetylase genes and their roles in anthocyanin biosynthesis in grape by Wen Tang, Feiyue Li, Danni Yang, Mengyu Xu, Jinggui Fang, Suwen Lu

“…Application of the deacetylase inhibitor sirtinol resulted in berry color changes and increased anthocyanin accumulation, suggesting that enhanced anthocyanin content in sirtinol-treated grape berry skins may result from post-translational modifications of genes involved in anthocyanin biosynthesis. …”
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Cyclosporine and Herbal Supplement Interactions by D. Colombo, L. Lunardon, G. Bellia

“…Although findings from animal studies cannot be directly translated into humans, avoiding concomitant use of herbal extracts is prudent until human clinical studies have ruled out any possible interaction. …”
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