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5701
Comprehensive analysis of lncRNAs and mRNAs revealed potential participants in the process of avian reovirus infection
Published 2025-02-01“…Notably, our study identified a novel functional lncRNA, MSTRG.9284.1 (It was named linc000889 in the present study), which inhibits the replication of ARV at the transcriptional, translational levels and viral titer. Overall, this study has identified numerous ARV-induced differentially expressed mRNAs and lncRNAs, including the functional lncRNA linc000889 that inhibits ARV replication. …”
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5702
What Drives Innovation and How Its Relevance is Established. A Perspective on Electric Vehicle Promotion in La Rochelle and Gothenburg : 1989-2000
Published 2018-01-01“…On all three levels by means of motivations, attitudes, vocabularies, and methods corporate cultures and agendas translate into the narratives arguing the relevance of territorial innovation.…”
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5703
Ippolit Bogdanovich and Voltaire’s 'Épître à l’impératrice de Russie': Adapting Praise
Published 2024-11-01“…This essay considers how his translation of Voltaire’s Épître à l’impératrice de Russie (1771) reworks a famous poem of praise. …”
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5704
Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins
Published 2024-11-01“…However, there is a lack of a systematic exploration of how these affect the identification of peptides, post-translational modifications (PTMs), proteins and their significance (through the False Discovery Rate) and correctness. …”
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5705
Exploring BCL2 regulation and upstream signaling transduction in venetoclax resistance in multiple myeloma: potential avenues for therapeutic intervention
Published 2025-02-01“…Simultaneous inhibition of MCL-1, BCL-XL, and upstream PI3K, RTK (FGF, EGF, and IGF1) mediated signaling enhanced VTX sensitivity. Post-translational modifications of MCL-1, particularly its stabilization via acetylation and phosphorylation, were investigated, although their inhibition only marginally increased VTX sensitivity. …”
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5706
Association between previous work experience in general healthcare and recovery orientation among mental health professionals during the COVID-19 pandemic in Japan
Published 2025-01-01“…Working with primary care helps professionals learn and translate the concept of recovery into practice. In Japan where primary care system is not established yet, previous work experience in general healthcare may substitute for the absence of primary care work experience. …”
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5707
Targeting PPARγ Signaling Cascade for the Prevention and Treatment of Prostate Cancer
Published 2012-01-01“…These TZD-derived novel therapeutic agents, alone or in combination with other anticancer drugs, have translational relevance in fostering effective strategies for cancer treatment. …”
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5708
Comprehensive transcriptome and proteome analysis revealed the molecular mechanisms of melatonin priming and waterlogging response in peach
Published 2025-02-01“…A correlation analysis between differentially expressed genes and proteins highlighted the regulation of numerous genes at both the transcriptional and translational levels. Furthermore, core DEGs/DEPs, including heat shock proteins and stress-related proteins, were identified. …”
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5709
Enhancing magnetic hyperthermia: Investigating iron oxide nanoparticle coating and stability
Published 2025-01-01“…Further research is essential for a better understanding of the cell death mechanism induced by MH and for its clinical translation.…”
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5710
Toponymie littorale aux îles Marquises, Fenua ‘Enata/Henua ‘Enana, Polynésie orientale (Polynésie française)
Published 2017-07-01“…There is still a lot to do to translate the underlying cultural essence of these places’ names.…”
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5711
Estimando la Cantidad de Forraje en Campos de Heno y Potreros
Published 2014-02-01“…Sollenberger. It was translated by J. Bosques, and published by the UF Department of Agronomy, January 2014. …”
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5712
Optimization of Conditions for Production of Soluble <i>E. coli</i> Poly(A)-Polymerase for Biotechnological Applications
Published 2025-01-01“…Rosetta 2 (DE3) and Rosetta Blue (DE3) hosting the pRARE plasmid exhibited the lowest solubility, likely due to excessive translation efficiency. Higher induction temperatures (>18 °C) exacerbated PAP 1’s insolubility. …”
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5713
Why do the Acehnese migrate? A study of the Hikayat Ranto from the socio-cultural perspective of Acehnese society
Published 2024-09-01“…This qualitative research focuses on linguistic texts as the subject of investigation, the Hikayat Ranto, written by Leube Isa and translated by Ramli Harun. The Acehnese people are renowned for their successful migration. …”
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5714
Dysfunction of G Protein-Coupled Receptor Kinases in Alzheimer's Disease
Published 2010-01-01“…Therefore, continuous efforts in this direction are necessary before translating the knowledge to any therapeutic strategies.…”
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5715
VALIDASI ST EUROPEAN QUALITY OF LIFE-5 DIMENSIONS (EQ-5D) VERSI INDONESIA PADA PASIEN HIPERTENSI DI PUSKESMAS KOTAGEDE II YOGYAKARTA
Published 2015-11-01“…The instrument used in this study is the EQ-5D which has been translated into Indonesian. Affordable population in this study were all patients with hypertension in Health Center Kotagede II Yogyakarta at May to June 2014. …”
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5716
Development and evaluation of a low-cost database solution for the Community Paramedicine at Clinic (CP@clinic) database.
Published 2024-12-01“…This solution to a healthcare database is translatable to other health research studies in which ongoing patient data is collected electronically and longitudinally.…”
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5717
Genetic advancements in breast cancer treatment: a review
Published 2025-02-01“…Continued collaboration between researchers and clinicians is essential to translate these innovations into clinical practice, ultimately improving BC patients' survival rates and quality of life.…”
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5718
Composite Tor traffic features extraction method of webpage in actual network flow based on SDN
Published 2022-03-01“…Website fingerprinting (WF) methods for Tor webpage traffic are often based on the separated Tor traffic or even the separated Tor webpage traffic.However, distinguishing Tor traffic from the original traffic of the actual network and Tor webpage traffic from the Tor traffic costs amount of computation, which is more difficult than the WF attack itself.According to the current architecture of the Internet and the characteristics of network traffic converging to regional central nodes, the bi-directional statistical feature (BSF) was proposed for distinguishing Tor traffic through the intra-domain global perspective provided by the SDN structure of the central node and the node information disclosed by the Tor network.Furthermore, a hidden feature extraction method for Web traffic based on lifted structure fingerprinting (LSF) was proposed, and a composited Tor-webpage-identification traffic feature (CTTF) was proposed based on BSF and LSF deep features.For solving the problem of traffic training data scarcity, a traffic data augmentation method based on translation was proposed, which made the augmented traffic data as consistent as the Tor traffic data captured in the real working environment.The experimental results show that the identification rate based on CTTF can be improved by about 4% compared with using only the original data features.When there is less training data, the classification accuracy is improved more obvious after using the traffic data augmentation method, and the false positive rate can be effectively reduced.…”
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5719
The role of epigenetics in plant pathogens interactions under the changing environments: A systematic review
Published 2025-03-01“…RNA methylation, particularly N6-methyladenosine (m6A), adds another layer of regulation, controlling the stability and translation of transcripts involved in host immunity and pathogen virulence. …”
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5720
Automated Detection of Macular Diseases by Optical Coherence Tomography and Artificial Intelligence Machine Learning of Optical Coherence Tomography Images
Published 2019-01-01“…Among them, 1,100 images were used for deep learning training, augmented to 59,400 by horizontal flipping, rotation, and translation. The remaining 100 images were used to evaluate the trained convolutional neural network (CNN) model. …”
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