Mechanism of modified mRNA structure in COVID-19 vaccines for inducing neutralizing antibodies by Sabighoh Zanjabila, Beti Ernawati Dewi

“…Structural modifications, such as replacing uridine with 1-methylpseudouridine (1mψ), enhance translation efficiency and help the mRNA evade immune detection. …”
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Improving research milieu in the medical colleges in India: Challenges and solutions by Gitanjali Batmanabane, Rituparna Maiti

“…The thesis has been a part of the postgraduate curriculum with the idea that as the resident does the project, they will also learn how to do research. In a bid to translate the thesis into publications, many professional bodies conduct workshops and courses during conferences on various aspects of scientific writing. …”
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A cross-entropy corrected hybrid multiconfiguration pair-density functional theory for complex molecular systems by Rulin Feng, Igor Ying Zhang, Xin Xu

“…Here, we extend the linear scheme of hybrid multiconfiguration pair-density functional theory (HMC-PDFT) by incorporating a cross-entropy ingredient to balance the description of static and dynamic correlation effects, leading to a consistent improvement on both exchange and correlation energies. The B3LYP-like translated on-top functional (tB4LYP) developed along this line not only surpasses the accuracy of its parent methods, the complete active space self-consistent field (CASSCF) and the original MC-PDFT functionals (tBLYP and tB3LYP), but also outperforms the widely used complete active space second-order perturbation theory (CASPT2). …”
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CDC40 suppression induces CDCA5 splicing defects and anti-proliferative effects in lung cancer cells by Die Hu, Brigitte L. Thériault, Vida Talebian, Laurent Hoffer, Julie Owen, Justin Lim, Benjamin J. Blencowe, Evelyne Lima-Fernandes, Punit Saraon, Richard Marcellus, Rima Al-awar

“…Global transcriptional and splicing changes were also investigated, where CDC40 knockdown resulted in perturbation of splicing- and translation-related genes as well as more transcripts with intron retention. …”
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Development of RNA interference-based therapy for rare genetic diseases by Milya Urfa Ahmad, Syarifah Dewi

“…RNAi employs small RNA molecules, such as small interfering RNA (siRNA) and microRNA (miRNA), to bind specific mRNA molecules and prevent their translation into proteins. Current research showed that RNAi-based therapies have the potential to treat various genetic diseases, including acute hepatic porphyria (AHP) and primary hyperoxaluria type 1 (PH1). …”
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What’s beyond the core? Database coverage in qualitative information reveal by Jennifer Horton, David Kaunelis, Danielle Rabb, Andrea Smith

“…This potential was investigated via tests on qualitative rapid review search strategies translated to Scopus to determine how the index may contribute relevant literature. …”
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Development and Validation of a Short Form of the German Self-Consciousness Scale for the General Population by Kyla Brophy, Matthew Emery, Adina Coroiu, Cornelia Albani, Elmar Braehler, Annett Körner

“…Abstract: Background: The German translation of the Self-Consciousness Scale (Fragebogen zur Erfassung dispositionaler Selbstaufmerksamkeit [SAM]) is a 27-item, self-report measure assessing self-consciousness. …”
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Role of aquaporins in brain water transport and edema by Yuyuan Li, Yining Wang, Xingda Huang, Hao Zhang, Youfei Guan, Xiaoyan Zhang

“…However, to date, these findings have not been translated into clinical practice. There is an urgent need to develop specific AQP inhibitors and activators to explore the potential benefits of modulating the functions of AQP1 and AQP4 in the context of brain edema.…”
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Mesoporous Prussian blue nanoparticle neuroconduit for the biological therapy targeting oxidative stress reduction, inflammation inhibition, and nerve regeneration by Junyi Zhu, Yijia Zhang, Yinuo Sun, Fangzheng Yu, Yang Lu, Qianqian Hu, Jiali Guo, Haijuan Zhang, Tianling Chen, Feifei Lian, Jian Wang, Xiaokun Li, Jian Xiao

“…This also establishes a theoretical foundation for exploring the integration and clinical translation between nanomaterials and biotherapy.…”
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Cell-free biodegradable electroactive scaffold for urinary bladder tissue regeneration by Rebecca L. Keate, Matthew I. Bury, Maria Mendez-Santos, Andres Gerena, Madeleine Goedegebuure, Jonathan Rivnay, Arun K. Sharma, Guillermo A. Ameer

“…However, in addition to safety and efficacy, translation of tissue engineering technology will depend on manufacturability, affordability, and ease of adoption. …”
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Brain receptor dynamics in early and adult life stress: Gateways to maladaptive coping strategies by Sora Shin

“…The brain receptor molecules are key mediators of these processes, translating neuromodulatory signals into neuronal responses or circuit activity changes that ultimately shape behavioral outcomes. …”
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Analytic two-loop four-point form factor of the stress-tensor supermultiplet in N $$ \mathcal{N} $$ = 4 SYM by Yuanhong Guo, Lei Wang, Gang Yang, Yixiong Yin

“…This form factor is analogous to the Higgs plus four-gluon amplitudes in the heavy-top limit of QCD when translated to the N $$ \mathcal{N} $$ = 4 SYM context. …”
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Research prospects for kidney xenotransplantation: a bibliometric analysis by Shujun Yang, Mingtao Zhang, Hao Wei, Bin Zhang, Jiang Peng, Panfeng Shang, Shengkun Sun

“…We found that ‘co-stimulation blockade’, ‘xenograft survival’, ‘pluripotent stem cell’, ‘translational research’, and ‘genetic engineering’ were likely to be the focus of attention in the coming years.Conclusions This study screened global publications related to xenogeneic kidney transplantation; analyzed their literature metrology characteristics; identified the most cited articles in the research field; understood the current situation, hot spots, and trends of global research; and provided future development directions for researchers and practitioners.…”
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smu_1558c-mediated regulation of growth and biofilm formation in Streptococcus mutans by Jing Zhou, Jing Zhou, Qizhao Ma, Qizhao Ma, Jingou Liang, Jingou Liang, Yangyang Pan, Yangyang Pan, Yang Chen, Yang Chen, Shuxing Yu, Shuxing Yu, Yaqi Liu, Yaqi Liu, Qiong Zhang, Qiong Zhang, Yuqing Li, Jing Zou, Jing Zou

“…Proteomic analysis revealed 166 differentially expressed proteins in the deletion mutant, with significant enrichment in pathways related to carbohydrate transport and metabolism, and translation. Notably, glucosyltransferases GtfB and GtfC, key enzymes in biofilm formation, were significantly downregulated in the deletion mutant, while ClpL, a Clp-like ATP-dependent protease involved in protein homeostasis under stress conditions, was highly upregulated. …”
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Monitoring Disease Progression and Therapeutic Response in a Disseminated Tumor Model for Non-Hodgkin Lymphoma by Bioluminescence Imaging by Margarethe Köberle, Kristin Müller, Manja Kamprad, Friedemann Horn, Markus Scholz

“…We conclude that well-established bioluminescence imaging is a valuable tool in disseminated xenograft tumor models. Our model can be translated to other cell lines and used to examine new therapeutic agents and schedules.…”
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A Lingual Agnostic Information Retrieval System by Umar Bn Abdullahi, Godspower Osaretin Ekuobase

“…Consequently, adopting the design science research methodology, we introduced a lingual agnostic IRS architecture designed on the principle of transparency on user language detection, information translations, and caching. The detailed design of the architecture was done using the unified modeling language. …”
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The Effect of Lysophosphatidic Acid during In Vitro Maturation of Bovine Oocytes: Embryonic Development and mRNA Abundances of Genes Involved in Apoptosis and Oocyte Competence by Dorota Boruszewska, Ana Catarina Torres, Ilona Kowalczyk-Zieba, Patricia Diniz, Mariana Batista, Luis Lopes-da-Costa, Izabela Woclawek-Potocka

“…LPA supplementation of maturation medium improves COC quality, and although this was not translated into an enhanced in vitro development until the blastocyst stage, improved oocyte competence may be relevant for subsequent in vivo survival.…”
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THE INTEGRATION OF EMERGING TECHNOLOGIES INTO INNOVATIVE SMART NATION PROJECTS AND SOLUTIONS by Laurențiu-Octavian MUTULEANU

“…Thus, Smart Nation projects and solutions would ensure the functions of accumulating, generating, and disseminating knowledge and innovation (technological and social), with the aim of developing human capital and translating these strategic advantages (knowledge, innovation, human capital) into innovative products and services for understanding and solving societal issues, ultimately contributing to the increase of community welfare.…”
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From Orality to Scriptuality : the Contribution of African Languages to the English Language Teaching by Andjou Frédéric KOUADIO

“…Today’s world is seen as a 'knowledge society' where knowledge has a universal character and is translated in the form of information through languages and by means of information and communication technologies. …”
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Sonatentheorien des Ostens. Zum Transfer einer westeuropäischen Formidee nach Russland und in die Sowjetunion bis 1945 by Wendelin Bitzan

“…. // This article examines the extent to which the orientation toward Western European theories of musical form – in particular, the academic paradigm of sonata form – is reflected in the writings of Russian and Soviet scholars of the nineteenth and twentieth centuries as well as in Russian translations of German and English treatises. By comparing how sonata terminology is used in the discussed writings, conclusions are developed concerning the transfer of analytical and compositional vocabulary from Western to Eastern Europe in the light of aesthetic theories associated with sonata form. …”
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