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5261
Current Status of Treatment of Spinal and Bulbar Muscular Atrophy
Published 2012-01-01“…Since ligand-induced nuclear translocation of mutant AR has been shown to be a critical step in motor neuron degeneration in SBMA, androgen deprivation therapies using leuprorelin and dutasteride have been developed and translated into clinical trials. Although the results of these trials are inconclusive, renewed clinical trials with more sophisticated design might prove the effectiveness of hormonal intervention in the near future. …”
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5262
Revolution of blood cancer treatment in the oral cavity: Breakthroughs in nanotherapy
Published 2024-09-01“…Future directions include individualized treatment plans, multifunctional nanoparticles, combination therapies, and improved nanoparticle design. The translation of these breakthroughs into clinical practice requires collaboration among researchers, physicians, and industry stakeholders. …”
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5263
Contemporary Evaluation and Management of the Diabetic Foot
Published 2012-01-01“…While these, increasingly expensive, therapies have shown promising results in clinical trials, the results have yet to be translated into widespread clinical practice leaving a huge scope for further research in this field.…”
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5264
The impact of terahertz radiation on an extremophilic archaean Halorubrum saccharovorum proteome
Published 2017-02-01“…The obtained data suggest that Halorubrum cells respond to exposure to terahertz radiation by expression changes in gene products involved in translation regulation.…”
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5265
Impact of Implant Angulation on Stress Distribution and Survival Rate of Implant-Supported Fixed Dental Prostheses: A Prospective Clinical Study
Published 2024-12-01“…Conclusion: While finite element analysis identified biomechanical differences associated with deviated implant angulation, these distinctions did not consistently translate into clinically significant variations.…”
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5266
The Adaptive Neuroplasticity Hypothesis of Behavioral Maintenance
Published 2012-01-01“…In this paper we will: (1) describe the enormous potential for neuroplasticity in older adults; (2) review stress and depression as examples of maladaptive neuroplasticity; (3) describe an example of adaptive neuroplasticity achieved with a behavioral intervention that induced positive affect in people with CHD; and (4) discuss implications for future work in bench to bedside translational research.…”
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5267
Effect of Superabsorbent Polymer (SAP) Internal Curing Agent on Carbonation Resistance and Hydration Performance of Cement Concrete
Published 2022-01-01“…The results showed that (i) when the particle size and dosage of SAP were 100 mesh and 0.200%, the carbonation depth of internally cured concrete was only 56.5% of the control group on day 28; (ii) the Ca(OH)2 absorption peak area of SAP-concrete in the FTIR spectra could be increased by 3.38 times than that of the control group, and more C2S and C3S were translated into Ca(OH)2, which helped to improve the hydration degree of cement concrete; (iii) the hydration products of day 56 were increased significantly and the remaining pores formed by SAP gels were gradually filled by hydration products, which enhanced the compactness and carbonation resistance of cement concrete.…”
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5268
Adjuvant Radiochemotherapy with a 23-Month Overall Survival Time in a Patient after a Surgery due to Splenic Hemangiosarcoma Rupture: A Case Report with the Literature Review
Published 2018-01-01“…Postoperative radiotherapy may increase local disease control, especially after nonradical operation, but this does not translate into improvement in overall survival time of these patients. …”
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5269
Indicating Dependency between Spoken Sentences by Prosodic Means
Published 2018-10-01“…The data are in Finnish, and they come from conference-like, monologous presentations that are translated by speech-to-text interpreters to allow the speech to be accessed by the deaf and hard-of-hearing. …”
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5270
The Brewer of Preston by Andrea Camilleri
Published 2018-02-01“…In contemporary Italian literature Andrea Camilleri’s career as a writer represents a successful story: in a couple of decades he has sold hundreds of thousands copies, has been translated into many languages, has won several awards, his books have been object of workshops. …”
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5271
The role of risk attitudes in shaping digital privacy preferences: evidence from a large-scale survey
Published 2025-01-01“…In addition, we observe that while these concerns translate into higher non-disclosure actions, the privacy paradox persists regardless of individuals’ risk attitudes. …”
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5272
Utilizing Cytokines to Function-Enable Human NK Cells for the Immunotherapy of Cancer
Published 2014-01-01“…Here, we review the roles of major cytokines that regulate human NK cell development, survival, and function, including IL-2, IL-12, IL-15, IL-18, and IL-21, and their translation to the clinic as immunotherapy agents. We highlight a recent development in NK cell biology, the identification of innate NK cell memory, and focus on cytokine-induced memory-like (CIML) NK cells that result from a brief, combined activation with IL-12, IL-15, and IL-18. …”
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5273
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5274
Assessing the health implications of anticholinergic drugs in older people
Published 2025-01-01Get full text
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5275
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5276
Corrigendum: Klebsiella pneumoniae biofilms and their role in disease pathogenesis
Published 2025-02-01Get full text
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5277
Multilingualism and Plurilingualism in Teaching the Lingua Franca: A Critical Review
Published 2023-09-01Get full text
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5278
Progress of nursing interventions on medication adherence in patients with hypertension (高血压患者服药依从性的护理进展)
Published 2023-12-01Get full text
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5279
Experimental Modeling and Treatment Strategies for Peritoneal Carcinomatosis
Published 2024-12-01Get full text
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5280
Research progress on interventions of aged frailty syndrome (老年衰弱综合征干预的研究进展)
Published 2024-10-01Get full text
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