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5201
Codon Usage is Influenced by Compositional Constraints in Genes Associated with Dementia
Published 2022-08-01“…Furthermore, parity analysis, higher translational selection value, preference of GC-ending codons over AT-ending codons, and association of gene length with gene expression refer to the dominant role of selection pressure with compositional constraint and mutational force-shaping codon usage.…”
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5202
Cross-cultural validation and psychometric properties study of the Chinese college students’ life skills scale for sport—transfer scale
Published 2025-01-01“…In the first phase, four translation experts and five academic researchers collaborated to develop the Chinese version of the scale (C-LSSS-TS). …”
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5203
Noninvasive Optical Imaging and In Vivo Cell Tracking of Indocyanine Green Labeled Human Stem Cells Transplanted at Superficial or In-Depth Tissue of SCID Mice
Published 2015-01-01“…Recent studies have shown how real-time in vivo molecular imaging has helped in identifying hurdles towards clinical translation and designing potential strategies that may contribute to successful transplantation of stem cells and improved outcomes. …”
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5204
Immunological Regulation of Fibrosis During Heart Failure: It Takes Two to Tango
Published 2025-01-01“…The aims of this review are to (i) briefly summarize the role of key immune cells that regulate wound healing during MI and fibrosis during LV remodeling; (ii) underscore phenotypic diversities in immune cells and their subsets to underscore their role in regulating fibrotic responses, and, last but not the least, (iii) highlight gaps in our understanding that restrict the translation of immuno-modulatory therapies from the preclinical models to heart failure patients.…”
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5205
Optimization of the intron sequences combined with the CMV promoter increases recombinant protein expression in CHO cells
Published 2025-01-01“…Transcriptomics analysis was performed and found that differential expression of genes involved in mRNA processing, RNA export from nucleus, cytoplasmic translation, transcriptional activation and cell cycle regulation. …”
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5206
2020 Cool-Season Forage Variety Recommendations for Florida
Published 2020-09-01“…These plants are usually higher in total digestible nutrients (TDN) and crude protein (CP) than summer perennial grasses, translating into greater animal performance (Dubeux et al., 2016). …”
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5207
Landscape analysis of m6A modification reveals the dysfunction of bone metabolism in osteoporosis mice
Published 2025-02-01“…The m6A modification, a prevalent form of chemical RNA modification, primarily regulates posttranscriptional processes, including RNA stability, splicing, and translation. Numerous studies have underscored the crucial functions of m6A regulators in OP. …”
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5208
Detection and Delineation of Oral Cancer With a PARP1-Targeted Optical Imaging Agent
Published 2017-08-01“…Intuitively, the addition of optical contrast could improve oral cancer detection and delineation, but so far no molecularly targeted approach has been translated. Our fluorescently labeled small-molecule inhibitor PARPi-FL binds to the DNA repair enzyme poly(ADP-ribose)polymerase 1 (PARP1) and is a potential diagnostic aid for oral cancer delineation. …”
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5209
The Critical Analysis of the Book “A’taTawor A’naHwi Le’loghate Al’Arabiy”
Published 2018-06-01“…In this paper, the book “A’taTawor A’naHwi Le’loghate Al’Arabiy” written by Bergeshter Eser(1994) and researched and translated by Ramazaan AbdA’ta’waab has been put into criticism. …”
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5210
GLP-1 Receptor Agonists and Cardiovascular Disease in Patients with Type 2 Diabetes
Published 2018-01-01“…GLP-1 RA actions not only translate on an improvement of well-known cardiovascular risk factors such as glycaemic control, dyslipidaemia, weight, or arterial hypertension but also might show benefits on endothelial function, coronary ischaemia, and heart failure. …”
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5211
Monte Carlo Simulations in Nanomedicine: Advancing Cancer Imaging and Therapy
Published 2025-01-01“…This topical review underscores the transformative potential of MC simulations in bridging fundamental research and clinical translation. By facilitating personalized nanomedicine and streamlining regulatory and clinical trial processes, MC simulations offer a pathway toward more effective, tailored, and accessible cancer treatments. …”
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5212
Ethanol-Induced Alterations of T Cells and Cytokines after Surgery in a Murine Infection Model
Published 2017-01-01“…Expression of transcription factors of T helper cell lineage commitment did not translate into different counts of T helper cells. …”
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5213
The Interstitial Lymphatic Peritoneal Mesothelium Axis in Portal Hypertensive Ascites: When in Danger, Go Back to the Sea
Published 2010-01-01“…The hypothetical comparison between the ascitic and the amniotic fluids allows for translational investigation. From a phylogenetic point of view, the ancestral mechanisms for amniotic fluid production were essential for animal survival out of the aquatic environment. …”
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5214
Wind Power Assessment Based on a WRF Wind Simulation with Developed Power Curve Modeling Methods
Published 2014-01-01“…Although the probability distribution functions (pdfs) of the wind speed are commonly used, their seemingly good performance for distribution may not always translate into an accurate assessment of power generation. …”
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5215
Indigeneity and Resistance in Zubair Ahmad’s Grieving for Pigeons
Published 2024-12-01“…These stories, originally written in Punjabi and translated into English by Anne Murphy, situate culture of the past in the future to come, by influencing people to embrace their culture, enabling it to adapt to new circumstances and achieve an elevated position where it becomes resistant against colonial exercise. …”
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5216
An Iterative, Mixed Usability Approach Applied to the Telekit System from the Danish TeleCare North Trial
Published 2016-01-01“…These violations were then translated into measurable values on a scale of 0 to 4 indicating degree of severity. …”
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5217
Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders
Published 2024-12-01“…Despite significant progress, challenges remain in translating these findings into clinically viable therapies. …”
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5218
Marine natural products as a source of novel anticancer drugs: an updated review (2019–2023)
Published 2025-01-01“…Furthermore, it addresses the challenges and opportunities associated with the development of marine-derived anticancer drugs, including issues related to supply, sustainability, synthesis, and clinical translation. Finally, the review underscores the immense potential of marine natural products as a valuable reservoir of novel anticancer agents and advocates for continued exploration and exploitation of the marine environment to address the unmet medical needs in cancer therapy Graphical Abstract…”
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5219
Nonviral Gene Delivery of Growth and Differentiation Factor 5 to Human Mesenchymal Stem Cells Injected into a 3D Bovine Intervertebral Disc Organ Culture System
Published 2013-01-01“…In this study we demonstrate the potential of GDF5 transfected MSC as a promising approach for clinical translation for disc regeneration.…”
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5220
miRNAs and Melanoma: How Are They Connected?
Published 2012-01-01“…miRNAs are non-coding RNAs that bind to mRNA targets and disturb their stability and/or translation, thus acting in gene posttranscriptional regulation. …”
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