Discordance, accuracy and reproducibility study of pathologists’ diagnosis of melanoma and melanocytic tumors by Sarah Haggenmüller, Christoph Wies, Julia Abels, Jana T. Winterstein, Lukas Heinlein, Carina Nogueira Garcia, Jochen S. Utikal, Sebastian A. Wohlfeil, Friedegund Meier, Sarah Hobelsberger, Frank F. Gellrich, Mildred Sergon, Axel Hauschild, Lars E. French, Lucie Heinzerling, Justin G. Schlager, Kamran Ghoreschi, Max Schlaak, Franz J. Hilke, Gabriela Poch, Sören Korsing, Cosimo Sarfert, Carola Berking, Markus V. Heppt, Michael Erdmann, Sebastian Haferkamp, Konstantin Drexler, Dirk Schadendorf, Wiebke Sondermann, Matthias Goebeler, Bastian Schilling, Jakob Nikolas Kather, Stefan Fröhling, Mar Llamas-Velasco, Luis C. Requena, Gerardo Ferrara, Maite Fernandez-Figueras, Sylvie Fraitag, Cornelia S. L. Müller, Hans Starz, Heinz Kutzner, Raymond Barnhill, Richard Carr, Kenneth S. Resnik, Stephan Alexander Braun, Tim Holland-Letz, Titus J. Brinker

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Epigenetic Inhibitors Differentially Impact TGF-β1 Signaling Cascades in COPD Airway Smooth Muscle Cells by Karosham Diren Reddy, Dikaia Xenaki, Ian M. Adcock, Brian G. G. Oliver, Razia Zakarya

“…However, a deeper understanding of the complex mechanisms associated with DNA methylation, histone post-translational changes and RNA methylation in the context of regulatory pathways remains to be elucidated. …”
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Qualitative Insights on Barriers to Receiving a Second Dose of Measles-Containing Vaccine (MCV2), Oromia Region of Ethiopia by Kalkidan Solomon, Brooke N. Aksnes, Abyot Bekele Woyessa, Chala Gari Sadi, Almea M. Matanock, Monica P. Shah, Paulos Samuel, Bekana Tolera, Birhanu Kenate, Abebe Bekele, Tesfaye Deti, Getachew Wako, Amsalu Shiferaw, Yohannes Lakew Tefera, Melkamu Ayalew Kokebie, Tatek Bogale Anbessie, Habtamu Teklie Wubie, Aaron Wallace, Ciara E. Sugerman, Mirgissa Kaba

“…Recorded data were transcribed, translated to English, and analyzed using ATLAS.ti v.09. …”
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Hypothyroidism impairs the circadian rhythmicity of clock genes and proteins involved in gut nutrient absorption in female mice by Ayla Secio-Silva, Paulo Henrique Evangelista-Silva, Felipe Emrich, Letícia Selvatici-Tolentino, Maíza Ferreira, Ana Bárbara de Paula Silva, Bruno Henrique Gomes, Tatienne Neder Figueira-Costa, André Gustavo Oliveira, Rodrigo Antonio Peliciari-Garcia, Francemilson Goulart-Silva, Paula Bargi-Souza

“…Moreover, our data suggest that the mechanisms triggered by thyroid hormones involve posttranscriptional and/or translational modifications of proteins related to lipid, protein, and carbohydrate absorption. …”
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Tracheostomy Practice in the Italian Intensive Care Units: A Point-Prevalence Survey by Raffaele Merola, Maria Vargas, Filippo Sanfilippo, Marco Vergano, Giovanni Mistraletti, Luigi Vetrugno, Gennaro De Pascale, Elena Giovanna Bignami, Giuseppe Servillo, Denise Battaglini

“…The overall prevalence of tracheostomy was found to be 9.1%, translating to a rate of 1.8 per 1000 admission days. …”
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Exploring lipidome mediated inflammatory pathways in acute pancreatitis using mendelian randomization by Wenbin Liu, Song Yang, Yuhan Li, Dava Tenzing, Ruizi Shi, Yang Jiang, Hao Deng, Enqiang Mao, Ying Chen, Yihui Wang

“…Further studies are warranted to confirm our observations in laboratory models and assess their translational value in developing AP preventive and therapeutic strategies.…”
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Assessing validity and reliability of the Transition Shock Scale for Undergraduate Nursing Students (TSS, Chinese version) in associate degree nursing students by Huiting Weng, Ziwei Ding, Li Yang, Bo Zhang, Yuanyuan Luo, Qin Wang

“…The TSS is a tool used in various countries and has been translated into Chinese; however, associate degree nurses dominate China’s nursing workforce, it needs to be validated in associate degree nursing interns. …”
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Prevalence, Indications, and Community Perceptions of Caesarean Section Delivery in Ngora District, Eastern Uganda: Mixed Method Study by Isaac Waniala, Sandra Nakiseka, Winnie Nambi, Isaac Naminya, Margret Osuban Ajeni, Jacob Iramiot, Rebecca Nekaka, Julius Nteziyaremye

“…Qualitative data analysis was done by transcribing and translating into English verbatim and then analyzed into themes and subthemes with the help of NVIVO 12. …”
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Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms by Inas M. Elgharib, Fatma M. Abdelhamid, Gehad E. Elshopakey, Hatem Sembawa, Talat A. Albukhari, Waheed A. Filimban, Rehab M. Bagadood, Mohamed E. El-Boshy, Engy F. Risha

“…Therefore, it is possible to conclude that CLO protects rats from inflammation, apoptosis, and hepatorenal oxidative damage caused by Cd poisoning. Comprehensive translational research is required to validate CLO’s efficacy and safety of use in humans. …”
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Comparative analysis of techno-economic and techno-environmental approach to optimal sizing and dispatch of hybrid solar–battery systems by Luka Smajila, Silvia Trevisan, Farzin Golzar, Ketan Vaidya, Rafael Guedez

“…The study also finds that reducing the levelised cost of energy (LCOE) or levelised carbon footprint (LCO2eq) from the investor perspective may not always translate into significant end-user benefits. This further highlights the importance of including various stakeholder perspectives in the analysis, especially in the context of decision support. …”
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Structural variability of sunflower gene for methionine-rich albumin SFA8 by I. N. Anisimova, N. V. Alpatieva, S. V. Goryunova, D. V. Goryunov, Al. V. Konarev, V. A. Gavrilova, E. E. Radchenko

“…The nucleotide and translated amino acid sequences are polymorphic among different genotypes. …”
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Virulence factor discovery identifies associations between the Fic gene family and Fap2+ fusobacteria in colorectal cancer microbiomes by Geicho Nakatsu, Duhyun Ko, Monia Michaud, Eric A. Franzosa, Xochitl C. Morgan, Curtis Huttenhower, Wendy S. Garrett

“…Here, we analyze genomes of Fusobacterium colon tumor isolates and find that a family of post-translational modification enzymes containing Fic domains is associated with Fap2 positivity in these strains. …”
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Resilience-based interventions in the public sector workplace: a systematic review by Malin H. L. Hollaar, Bram Kemmere, Paul L. Kocken, Semiha Denktaş

“…Therefore, the aim of this systematic review is (1) to identify how resilience is defined within different workplace interventions, translated into intervention content, and measured in these interventions; and (2) to synthesize the effectiveness of these interventions. …”
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A qualitative process evaluation of SBIRT implementation in pediatric trauma centers using the Science to Service Laboratory implementation strategy by Kelli Scott, Michael J. Mello, Geraldine Almonte, Emely Arenas Lemus, Julie R. Bromberg, Janette Baird, Anthony Spirito, Mark R. Zonfrillo, Karla Lawson, Lois K. Lee, Emily Christison-Lagay, Stephanie Ruest, Jeremy Aidlen, Andrew Kiragu, Charles Pruitt, Isam Nasr, Robert Todd Maxson, Beth Ebel, Sara J. Becker

“…Qualitative interviews were recorded, transcribed, and analyzed by two coders using a directed content analysis approach in NVivo software. Codes were then translated into frequently endorsed themes by the IAMSBIRT study research team. …”
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Performance Evaluation of a Preclinical SPECT Scanner with a Collimator Designed for Medium-Sized Animals by Yohji Matsusaka, Rudolf A. Werner, Paula Arias-Loza, Naoko Nose, Takanori Sasaki, Xinyu Chen, Constantin Lapa, Takahiro Higuchi

“…Along with its unique features of SPECT molecular functional imaging is a superior collimator technology that is applicable to medium-sized animal models and thus may promote translational research for diagnostic purposes and development of novel therapeutics.…”
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Is the convergence insufficiency symptom survey applicable to elderly individuals? by Saeid Abdi, Haleh Kangari, Saeed Rahmani, Alireza Akbarzadeh Baghban, Zahra Kamary Rad

“…Refraction, cover test, near point of convergence, and positive fusional ranges were examined. The Persian translated CISS was administered twice, once in the first session and 7 to 14 days later. …”
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Elevated miR-221-3p inhibits epithelial–mesenchymal transition and biochemical recurrence of prostate cancer via targeting KPNA2: an evidence-based and knowledge-guided strategy by Dingchao Li, Jingang Jian, Manhong Shi, Zihao Chen, Anguo Zhao, Xuedong Wei, Yuhua Huang, Yalan Chen, Jianquan Hou, Yuxin Lin

“…Conclusions miR-221-3p down-regulation was a risk factor for PCa BRFS, and its over-expression could inhibit the malignant phenotype and EMT of PCa cells by directly targeting KPNA2. Translational and personalized applications of the findings will be conducted in the future.…”
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Hotspots in peril: Misalignment of conservation efforts and ecological values in a shallow coastal sea by Kasper J. Meijer, Oscar Franken, Sterre Witte, Sander J. Holthuijsen, Tjisse van der Heide, Laura L. Govers, Han Olff

“…We first spatially overlay and translate the different protection measures to international standards. …”
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Timely access to specialist outpatient care: can applying systems thinking unblock our waiting lists? by Sue McAvoy, Agnes Toth-Peter, Ninad Jagdish, Bao Hoang Nguyen, Allison Arnott, Lisa Nissen

“…The project brought together researchers, consumers, hospital and health services (HHS) specialty clinical leads, General Practitioners (GPs), Executive sponsors, HHS outpatient service managers and analysts to provide hospital and healthcare expert stakeholders an opportunity to translate their collective mental models into meaningful system diagrams which communicated how the outpatient system was working. …”
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How have interventions targeting pregnant women from refugee, migrant and culturally and linguistically diverse backgrounds living in high-income countries been developed or tailor... by Sweekriti Sharma, Gayathri Jegadeesh, Camille Raynes-Greenow, Adrienne Gordon, Gayani Gunawardhana, Danielle Marie Muscat

“…Approaches to tailoring included the use of interpreters and translated materials, linking women to existing community resources and networks and community outreach delivered to women outside of hospital settings. …”
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