Modelling the epidemiological and economic impact of digital adherence technologies with differentiated care for tuberculosis treatment in Ethiopia by Richard White, Katherine L Fielding, Salome Charalambous, Nicola Foster, Degu Jerene, Andrew Mganga, Taye Letta, Job van Rest, Amare Worku Tadesse, Rein MGJ Houben, Ahmed Bedru, Kristian van Kalmthout, Christopher Finn McQuaid, Lara Goscé, Jense van der Wal, Martin J Harker, Norma Madden, Tofik Abdurhman, Demekech Gadissa, Tanyaradzwa N Dube, Jason Alacapa, Natasha Deyanova

“…However, our analysis also found large total provider and patient cost savings (US$163 (95% UI US$118; US$211) and US$3 (95%UI: US$1; US$5), respectively, over 2023–2035), translating to a 50.2% (95% UI 35.9%; 65.2%) reduction in total cost of treatment. …”
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Reproductive health literacy scale: a tool to measure the effectiveness of health literacy training by Maha Rauf, Zahra Goliaei, Lana Machta, Jenny Chang, Heike Thiel de Bocanegra

“…After content validity and face validity of the adapted scale, it was translated into Dari, Arabic, and Pashto and was administered to participants of RH literacy training sessions. …”
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Validation of a data-driven motion-compensated PET brain image reconstruction algorithm in clinical patients using four radiotracers by Ole L. Munk, Anders B. Rodell, Patricia B. Danielsen, Josefine R. Madsen, Mie T. Sørensen, Niels Okkels, Jacob Horsager, Katrine B. Andersen, Per Borghammer, Joel Aanerud, Judson Jones, Inki Hong, Sven Zuehlsdorff

“…Results The Hoffman brain phantom study demonstrated the algorithm’s capability to detect and correct for even minimal movements, 1-mm translations and 1⁰ rotations, applied to the phantom. …”
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Standardization and Quality Control of the Herbal Medicine Mist Nibima, Employed to Treat Malaria and COVID-19, Using Physicochemical and Organoleptic Parameters and Quantification... by Emmanuel Kofi Kumatia, Francis Ofosu-Koranteng, Alfred Ampomah Appiah, Kofi Bobi Barimah

“…Administration of a single oral therapeutic dose (30 mL) of Mist Nibima corresponds to ingestion of 559.2 ± 7.662, 505.5 ± 6.930, 312.6 ± 4.285, 76.8 ± 1.028, and 51.0 ± 0.699 µg of methyl cryptolepinoate, cryptolepine, quindoline, 11-isopropylcryptolepine, and hydroxycryptolepine, respectively. This translates into a corresponding daily dose of 1677.6 ± 22.986, 1516.5 ± 20.790, 937.8 ± 12.855, 230.4 ± 3.084, and 153.0 ± 2.097 µg of methyl cryptolepinoate, cryptolepine, quindoline, 11-isopropylcryptolepine, and hydroxycryptolepine. …”
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Comparative assessment of difficulty scales for removal of the third molar of the lower jaw depending on its position by O.O. Gudarian, Zh.M. Nekhanevуch, T.O. Kycherenko, A.V. Shepelya

“…Each of the difficulty scales was presented and translated into Ukrainian for convenient use in the practice of a dental surgeon. …”
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Genotyped cluster investigations versus standard contact tracing: comparative impact on latent tuberculosis infection cascade of care in a low-incidence region by Michael Asare-Baah, Marie Nancy Séraphin, LaTweika A.T. Salmon-Trejo, Lori Johnston, Lina Dominique, David Ashkin, Krishna Vaddiparti, Awewura Kwara, Anthony T. Maurelli, Michael Lauzardo

“…Although genotyped cluster investigations may be superior to contact investigations in generating additional epidemiological links, this may not necessarily translate into reducing infections. Here, we investigated the impact of genotyped cluster investigations compared to standard contact investigations on the LTBI care cascade in a low incidence setting. …”
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Emergency volunteering willingness and participation: a cross-sectional survey of residents in northern China by Hong Sun, Chaojie Liu, Wei Xu, Ye Li, Qunhong Wu, Lijun Gao, Zheng Kang, Yanhua Hao, Ning Ning, Mingli Jiao, Libo Liang, Yu Cui, Mengli Shi, Chao Liang, Xiaowen Zhao, Jie Fei, Qiuyu Wei, Ming Yi

“…Efforts should be made to translate willingness into effective contributions to the emergency response system. …”
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Automatic image generation and stage prediction of breast cancer immunobiological through a proposed IHC-GAN model by Afaf Saad, Noha Ghatwary, Safa M. Gasser, Mohamed S. ElMahallawy

“…Our findings demonstrate promising results in translating H&E images to IHC-equivalent representations, offering a potential solution to reduce the costs associated with traditional HER2 assessment methods. …”
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Assessment of ChatGPT-generated medical Arabic responses for patients with metabolic dysfunction-associated steatotic liver disease. by Saleh A Alqahtani, Reem S AlAhmed, Waleed S AlOmaim, Saad Alghamdi, Waleed Al-Hamoudi, Khalid Ibrahim Bzeizi, Ali Albenmousa, Alessio Aghemo, Nicola Pugliese, Cesare Hassan, Faisal A Abaalkhail

“…<h4>Methods</h4>An English patient questionnaire on MASLD was translated to Arabic. The Arabic questions were then entered into ChatGPT 3.5 on November 12, 2023. …”
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Generation and miRNA Characterization of Equine Induced Pluripotent Stem Cells Derived from Fetal and Adult Multipotent Tissues by Laís Vicari de Figueiredo Pessôa, Pedro Ratto Lisboa Pires, Maite del Collado, Naira Caroline Godoy Pieri, Kaiana Recchia, Aline Fernanda Souza, Felipe Perecin, Juliano Coelho da Silveira, André Furugen Cesar de Andrade, Carlos Eduardo Ambrosio, Fabiana Fernandes Bressan, Flavio Vieira Meirelles

“…We hypothesize that different cell types respond differently to the reprogramming process; thus, the goals of this study were to isolate and characterize equine adult and fetal cells and induce these cells to pluripotency for future regenerative and translational purposes. Methods. Adult equine fibroblasts (eFibros) and mesenchymal cells derived from the bone marrow (eBMmsc), adipose tissue (eADmsc), and umbilical cord tissue (eUCmsc) were isolated, their multipotency was characterized, and the cells were induced in vitro into pluripotency (eiPSCs). eiPSCs were generated through a lentiviral system using the factors OCT4, SOX2, c-MYC, and KLF4. …”
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Qualitative evaluation of the Rehabilitation Exercise and psycholoGical support After COVID-19 InfectioN (REGAIN) randomised controlled trial (RCT): ‘you are not alone’ by Gordon McGregor, Susanne Finnegan, Martin Underwood, Joyce Yeung, James Mason, Peter Heine, Nigel Edwards, Julie Bruce, Kate Seers, Harbinder Kaur Sandhu, Helen Atherton, Sharisse Alleyne, Katie Booth, Ranjit Lall, Vivien P Nichols, Stuart Ennis, Scott McGuire, Rachel Potter, Jessica Smith, Chen Ji, Shilpa Patel, Henry Nwankwo, Kate Evans, Susie Hennings, Alastair Canaway, Grace Lobley, David Mcwilliams, Christina Jones, Emma Padfield, David Montgomery, Beatriz Lara, Becky Haley, Francesca Denton, Bartholomew Sheehan, Mariam Ratna, Elaine Fairbrother, Zoe Noakes, Bogdan Zutic, Lee Austin, Tom Forsyth, Anne Bush, Alan Bush, Patrick Sawdon, Jonathon Prosser, Lee Tompkins, Jonathon Guck, Danielle Hale, Juwairia Said, Georgie Ray, Rowena Williams, Gail Evans, Thillini Hettiarachchi, Abeesh Panicker

“…The themes from group exercise were: (1) monitoring and modification of the online exercise; (2) catering for differing abilities; (3) feeling safe and confident to exercise; (4) progression of fitness; (5) optimal timing in the recovery trajectory; (6) group effect; (7) initial apprehension about exercise group; (8) gauging exercise capabilities; (9) translating exercises into life; and (10) on-demand supplementary videos. …”
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Transformation and articulation of clinical data to understand students’ clinical reasoning: a scoping review by Marie-France Deschênes, Nicolas Fernandez, Kathleen Lechasseur, Marie-Ève Caty, Busra Meryem Uctu, Yasmine Bouzeghrane, Patrick Lavoie

“…The learning tasks comprised, among others, identifying key findings, translating clinical information, synthesizing cases aloud, and writing a summary statement. …”
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NLRP3 inflammasome-modulated angiogenic function of EPC via PI3K/ Akt/mTOR pathway in diabetic myocardial infarction by Jia-Peng Li, Shu Qiu, Guang-Jie Tai, Yi-Ming Liu, Wei Wei, Meng-Meng Fu, Pan-Qi Fang, Joseph Nicolao Otieno, Tungalag Battulga, Xiao-Xue Li, Ming Xu

“…Cardiac functional outcomes in recipient mice after intramyocardial injection of shNlrp3 EPC overexpressing CEBPB or USP14 validated the modulation of EPC function by regulating Nlrp3 transcription or post-translational modification. Furthermore, KEGG enrichment and validation at the protein levels revealed PI3K/ Akt/mTOR cascade might be a downstream signal for NLRP3 inflammasome. …”
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Early assessment of IL8 and PD1+ Treg predicts response and guides treatment monitoring in cemiplimab-treated cutaneous squamous cell carcinoma by Teresa Troiani, Fabiana Napolitano, Luigi Formisano, Roberto Bianco, Daniela Russo, Daniela Esposito, Giuseppe Ercolano, Angela Ianaro, Alberto Servetto, Daniela Claudia Maresca, Marcella Scala, Annarita Amato, Stefania Belli, Claudia Maria Ascione, Angela Vallefuoco, Giovanna Attanasio, Fabio Somma, Silvia Varricchio, Massimo Mascolo, Claudia Costa, Alessia Villani, Massimiliano Scalvenzi, Gianfranco Orlandino

“…However, reliable biomarkers for patient selection are still lacking.Experimental design In this translational study, clinical annotations, tissue and liquid biopsies were acquired to investigate the association between sustained objective responses and transcriptional profiles, immune cell dynamics in tumor tissue and peripheral blood samples, as well as circulating cytokine levels.Results First, we investigated the baseline characteristics of the immune landscape of cSCC biopsies. …”
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A role for qualitative methods in researching Twitter data on a popular science article's communication by Travis Noakes, Corrie Susanna Uys, Patricia Ann Harpur, Izak van Zyl

“…The analysis also uncovered practices, such as language localization, where a title was translated from English to Spanish to reach broader audiences. …”
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Kazakh khans of the 15th–17th centuries in the scientific heritage of Shigabutdin Marjani by Atygayev N.A.

“…The scientific novelty of the study is that in this work, for the first time, the information about the Kazakh khans of the 15th–17th centuries, which are contained in the scientific works of Marjani, are highlighted and some errors in their translations into Russian are revealed.…”
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Computational pathology assessments of cardiac stromal remodeling: Clinical correlates and prognostic implications in heart transplantation by Eliot G. Peyster, MD, MSc, Cai Yuan, PhD, Sara Arabyarmohammadi, PhD, Priti Lal, MD, Michael D. Feldman, MD, PhD, Pingfu Fu, PhD, Kenneth B. Margulies, MD, MS, Anant Madabhushi, PhD, FAIMBE, FIEEE, FNAI

“…Computational pathology analysis of allograft stroma yields translationally relevant biomarkers, identifying accelerated remodeling before adverse outcomes occur. …”
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Assessment, Decision, Adaptation, Production, Topical Experts-Integration, Training, and Testing (ADAPT-ITT) Framework to Tailor Evidence-Based Posttraumatic Stress Disorder Treatm... by Cristina M Lopez, Angela D Moreland, Stephanie Amaya, Erin Bisca, Christin Mujica, Tayler Wilson, Nathaniel Baker, Lauren Richey, Allison Ross Eckard, Patricia A Resick, Steven A Safren, Carla Kmett Danielson

“…ResultsAfter challenging stigma-related appraisals, participants expressed feeling less constrained by maladaptive thoughts. These shifts translated to increased self-efficacy with both HIV-related care and mental health. …”
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Structure–Activity Relationship Studies of Tetracyclic Pyrrolocarbazoles Inhibiting Heterotetrameric Protein Kinase CK2 by Lukas Kröger, Sebastian Borgert, Miriam Lauwers, Michaela Steinkrüger, Joachim Jose, Markus Pietsch, Bernhard Wünsch

“…The strong inhibition of the CK2α/CK2β association by the histidine derivative (+)-<b>20a</b> (<i>K</i>_i = 6.1 µM) translated into a high inhibition of the kinase activity of the CK2 holoenzyme (CK2α₂β₂, IC₅₀ = 2.5 µM). …”
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A qualitative investigation of the influences of gender among low-socioeconomic status students’ motivations to study biology by Svetlana Masjutina, Elizabeth Stearns

“…Yet the ways LSES men and women translated their preferences and motivations into biology majors were divergent, which highlights the unique perspectives and challenges of LSES students along their motivational trajectories. …”
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