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6341
Health care provider's perceived factors for the increased practice of caesarean delivery in North West Amhara referral hospitals, Ethiopia, 2022: a qualitative study
Published 2025-02-01“…Transcribed interviews were translated coded and finally thematic analyses were employed using Open Code 4.0 software.ResultsHealthcare providers observed a significant increase in the frequency of caesarean deliveries. …”
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6342
Slaying axion-like particles via gravitational waves and primordial black holes from supercooled phase transition
Published 2024-12-01“…Similarly, depending on the ALP couplings to other Standard Model particles, the ALP constraints on f a can be translated into a lower bound on the PBH mass scale. …”
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6343
RUBY® – a tetravalent (2+2) bispecific antibody format with excellent functionality and IgG-like stability, pharmacology and developability properties
Published 2024-12-01“…Also, retained interaction with FcRn is demonstrated to translate into a pharmacokinetic profile in mice and non-human primates that is comparable to mAb controls. …”
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6344
Bionic nanovesicles sequentially treat flaps with different durations of ischemia by thrombolysis and prevention of ischemia-reperfusion injury
Published 2025-04-01“…Specifically, we have successfully constructed a clinical-grade bionic vesicle, UK-PBNZ@PM, a system that cleverly incorporates drug components that have been widely used in clinical applications, thereby demonstrating a high degree of clinical translational potential. Prussian blue nano-enzymes (PBNZ) are the core component and demonstrate remarkable efficacy against ischemia-reperfusion injury due to their excellent biocompatibility, robust reactive oxygen species (ROS) scavenging capacity and anti-inflammatory properties. …”
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6345
Enhancing Cluster Accuracy in Diabetes Multimorbidity With Dirichlet Process Mixture Models
Published 2025-01-01“…Results show that DPMM consistently outperforms traditional methods in clustering high-dimensional and imbalanced datasets, offering significant translational potential for guiding tailored healthcare strategies for complex chronic diseases and optimizing healthcare resource allocation.…”
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6346
Mitochondria-Targeted Biomaterials-Regulating Macrophage Polarization Opens New Perspectives for Disease Treatment
Published 2025-02-01“…Finally, the prospects and challenges of the use of these biomaterials in disease modulation have been explored, emphasizing their potential to be translated to the clinic. It is anticipated that this review will serve as a valuable resource for materials scientists and clinicians in the development of next-generation mitochondria-targeted biomaterials.Keywords: macrophages, polarization, biomaterials, mitochondria…”
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6347
Evaluation of antibiotic treatment initiation and duration practices in primary care. Cross-sectional study in two French multi-professional health centers.
Published 2024-01-01“…For nasopharyngitis, the high frequency of this condition translates into potentially large prescribing volumes on a collective scale. …”
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6348
Exhausting the (Human) Problem
Published 2024-12-01“…Their plastic techniques translate into corporeal masses of alternative enfleshments that resist both completion and categorization. …”
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6349
Protective effects of wogonin in the treatment of central nervous system and degenerative diseases
Published 2025-02-01“…Future researchers need to further explore the long-term efficacy and safety of wogonin in clinical trials and translate it for early application in the clinical treatment of true CNS disorders.…”
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6350
Analyzing and Visualizing Uncertain Knowledge: The Use of TEI Annotations in the PROVIDEDH Open Science Platform
Published 2022-09-01“…Then we describe use cases of annotations available on the platform, and how they translate into TEI annotations. Creating and interpreting annotations with and without uncertainty should now be easier, especially for researchers who do not know TEI markup.…”
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6351
Analysis of the role of acetylation in Giardia lamblia and the giardicidal potential of garcinol
Published 2025-01-01“…IntroductionPost-translational modifications of proteins provide cellular physiology with a broad range of adaptability to the external environment flexibly and rapidly. …”
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6352
The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function.
Published 2011-04-01“…Using targeted gene knock-out, we show that a single site-specific recombinase RecV is required for CwpV phase variation. CwpV is post-translationally cleaved at a conserved site leading to formation of a complex of cleavage products. …”
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6353
Action against birth defects: if not now, when?
Published 2024-12-01“…More births and better survival without effective prevention and treatment for birth defects translates into more mortality and disability from birth defects. …”
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6354
Multilingualism in Lithuanian Children’s Folklore
Published 2024-12-01“…In Lithuanian folklore, two major influences can be traced: Russian influence, particularly from World War II until the beginning of the 21st century, and influence from English-speaking countries, beginning in the 1990s and continuing to the present. Children translate folklore, sometimes word for word, adapt foreign texts, plots, traditions, take over certain genres, or integrate separate words or phrases from other languages into Lithuanian folklore.…”
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6355
Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity
Published 2025-01-01“…Platelet reactivity controlled by Ago2 reflects sex-specific regulation of gene expression potentially at both transcriptional and translational levels in megakaryocytes and platelets.…”
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6356
Exploring the nexus between banking stability and market value: Evidence from the Iraqi banking sector
Published 2024-05-01“…Banks with strong risk management practices, adequate capital buffers, and effective regulatory oversight inspire greater confidence among depositors and investors, translating into higher market valuations. Conversely, banks facing poor governance, high non-performing loans, and thin capital cushions struggle to achieve stability, eroding their market value. …”
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6357
Mia Couto and the enchantment of rain
Published 2025-01-01“…Although he rejected the label ‘magic realist’, his translator Chabal argues that in his stories the fantastic ‘transmutes the fictitious into the factual’ so that ‘all boundaries are put into question’: between past and present, far and near, material and spiritual. …”
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6358
Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells
Published 2025-01-01“…In conclusion, small animal studies have demonstrated the feasibility of high-throughput approaches for the discovery of pMHC epitopes recognised by directly alloreactive T cells. Translating this approach to the human setting is achievable and will yield both critical insights into the fundamental basis of alloreactivity and powerful tools for immune monitoring in transplantation.…”
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6359
Pruning and optimization of optical neural network as a binary optical trigger
Published 2025-01-01“…We demonstrate in simulation that the pruning methodology achieves at least 50% less MZI usage compared to Clements and Reck meshes with the same input size, translating to at least between 4.6% and 24.2% savings in power consumption and a 40% reduction in physical circuitry footprint compared to other proposed unitary MZI topologies, sacrificing only 1%–2% drop in inference accuracy.…”
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6360
Exploring Current Evidence on the Past, the Present, and the Future of the Heart Team: A Narrative Review
Published 2020-01-01“…Finally, these facts should be translated into better cardiovascular outcomes and a lower psychological distress among Team participants. …”
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