Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics by Naureen Rashid, Zhijian Hu, Asha Jacob, Ping Wang

“…In addition, we emphasize on the challenges to the translational phase and caution that the therapy should allow the immune system to continue to function well against secondary infections during hospitalization.…”
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Protein Ubiquitylation in Pancreatic Cancer by Thomas Bonacci, Julie Roignot, Philippe Soubeyran

“…Whereas it has been known for more than 3 decades now, ubiquitylation is a post-translational modification of protein that only recently emerged as a major regulator of many biological functions, dependent and independent on the proteasome, whose failure is involved in many human diseases, including cancer. …”
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The role of ferroptosis in colorectal cancer and its potential synergy with immunotherapy by Wenhua Xia, Wenhua Xia, Yuanhao Lv, Yuanhao Lv, Yan Zou, Zhanting Kang, Zhaoyi Li, Jiaqi Tian, Hongyan Zhou, Wei Su, Wei Su, Jiateng Zhong, Jiateng Zhong, Jiateng Zhong, Jiateng Zhong

“…In summary, ferroptosis offers a promising strategy to overcome CRC therapy resistance and enhance immunotherapy efficacy, warranting further investigation and translational application.…”
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Stakeholder perspectives to inform the implementation of a community health worker-delivered home management of hypertension intervention in Zimbabwe by Paddington Tinashe Mundagowa, Malvin Musariri, Pamela Magande, Tendai Hlabangana, Linda Jane Mukwambo, Pemberai Zambezi, Priscillah Muchemwa-Munasirei, Fadzai Mukora-Mutseyekwa

“…Objective Implementing evidence-based innovations often fails to translate into meaningful outcomes in practice due to dynamic real-world contextual factors. …”
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What impact has the NIHR Academic Clinical Fellowship (ACF) scheme had on clinical academic careers in England over the last 10 years? A retrospective study by James Neilson, David Jones, Sally Clough, James Fenton, Helen Harris-Joseph, Leesa Rayton, Caroline Magee, Lisa Ann Cotterill

“…Previous ACFs continue to show positive career progression, predominantly in translational and clinical research. The knowledge acquired during the ACF continues to be useful in subsequent roles and trainees would recommend the scheme to others.Conclusions The NIHR ACF scheme is successful as part of an integrated training pathway in developing careers in academic medicine and dentistry.…”
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The Influence of Multilingualism on the Works of Vasily Sesemann by Julia V. Sokolova

“…Sesemann’s special attitude to language, including: musical auditory and performing experience, teaching, and work as a translator. In addition, the study demonstrates V. Sesemann’s clear awareness of the opportunities provided by knowledge of several languages, which is supported by the philosopher’s statements and fragments from his children’s memoirs. …”
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MoS₂–Plasmonic Hybrid Platforms: Next-Generation Tools for Biological Applications by Nayra A. M. Moussa, Seungah Lee, Seong Ho Kang

“…Despite the promising advancements of MoS₂–plasmonic hybrids, translating these platforms into clinical practice requires overcoming considerable challenges, such as synthesis reproducibility, toxicity, stability in physiological conditions, targeted delivery, and scalable manufacturing. …”
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Advancing precision cancer immunotherapy drug development, administration, and response prediction with AI-enabled Raman spectroscopy by Jay Chadokiya, Kai Chang, Saurabh Sharma, Jack Hu, Jennie R. Lill, Jennifer Dionne, Jennifer Dionne, Jennifer Dionne, Amanda Kirane

“…Lastly, we highlight the translational potential of Raman for its integration in clinical practice for safe and precise patient-centric immunotherapy.…”
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Advances, challenges and future applications of liver organoids in experimental regenerative medicine by Da Gong, Jiaye Mo, Jiaye Mo, Mei Zhai, Fulin Zhou, Guocai Wang, Shaohua Ma, Xiaoyong Dai, Xiaoyong Dai, Xuesong Deng

“…However, a robust model and carrier that closely resemble human physiology are still lacking for translating these theories into practice. The potential for liver regeneration has been a central focus of ongoing research. …”
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Characterization of lysine acetyltransferase and deacetylase genes and their roles in anthocyanin biosynthesis in grape by Wen Tang, Feiyue Li, Danni Yang, Mengyu Xu, Jinggui Fang, Suwen Lu

“…Application of the deacetylase inhibitor sirtinol resulted in berry color changes and increased anthocyanin accumulation, suggesting that enhanced anthocyanin content in sirtinol-treated grape berry skins may result from post-translational modifications of genes involved in anthocyanin biosynthesis. …”
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Cyclosporine and Herbal Supplement Interactions by D. Colombo, L. Lunardon, G. Bellia

“…Although findings from animal studies cannot be directly translated into humans, avoiding concomitant use of herbal extracts is prudent until human clinical studies have ruled out any possible interaction. …”
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Personalized prediction of anticancer potential of non-oncology drugs through learning from genome derived molecular pathways by Xiaobao Dong, Huanhuan Liu, Ting Tong, Liuxing Wu, Jianhua Wang, Tianyi You, Yongjian Wei, Xianfu Yi, Hongxi Yang, Jie Hu, Haitao Wang, Xiaoyan Wang, Mulin Jun Li

“…However, the high cost of drug development limits our ability to translate this knowledge into precise treatments. Approved non-oncology drugs, comprising a large repository of chemical entities, offer a promising avenue for repurposing in cancer therapy. …”
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OPTIMIZING POWER SECTOR TRANSITION PATHWAYS IN RENEWABLE ENERGY-SCARCE REGIONS: AN OPERATIONAL RESEARCH APPROACH TO HUNAN PROVINCE UNDER CARBON PEAK GOALS by Caixia Yang, Yao Xiao, Buncha Wattana

“…The findings reveal that under the APS scenario, the share of coal-fired power would decrease by about 20%, translating to an estimated reduction of 50 million tons of CO2 emissions. …”
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Dysplastic L5-S1 Spondyloptosis in a 3-Year-Old Child: A Case Report and Review of the Literature by Vikas Tandon, Rahul Kaul, Harvinder Singh Chhabra, Ankur Nanda

“…During initial stage she underwent posterior decompression along L5-S1 segment including exposure of bilateral L5 and S1 nerve roots followed by instrumented reduction (L3-S2 5.5 mm pedicle screws) utilizing a rotational-translational technique. No interbody fusion was done at L5-S1 level and inner nuts of bilateral L3, L4, and S2 screws were intentionally kept loose. …”
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Potentials of hydrogen economy in energy transition towards 2050 net zero emission agenda: Opportunities for Nigeria by Abubakar S. Sambo, Abdullahi Adamu

“…However, changing global energy dynamics mean that resource-holders cannot assume that their oil resources will translate into reliable future revenues. Accelerated energy transitions would result in lower demand and prices for hydrocarbons can cut sharply into future revenues. …”
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The genus Cortinarius should not (yet) be split by Brigida Gallone, Thomas W. Kuyper, Jorinde Nuytinck

“…Moreover, considering that phylogenetic uncertainty translates to taxonomic uncertainty, we advise for careful evaluation of phylogenomic datasets before proposing radical taxonomic and nomenclatural changes.…”
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Effective optical and treatment zone analysis by means of cross-over differences after lenticule extraction by Hamed Haidari, Victor Derhartunian, Thomas Magnago, Maren-Christina Lengle, Samuel Arba-Mosquera

“…Conclusions: The method provides a reliable and objective way to determine the size of a lenticule of tissue extracted from a cornea and it can be applied to any topo- or tomographic derived metric. Translational relevance: To determine the size of the effective optical and treatment zones after laser vision correction, a fully automated method was developed. …”
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Empirical modeling potential transfer of land cover change pa city with neural network algorithms by fatemeh mohammadyary, hamidreza pourkhabbaz, hossin aghdar, morteza Tavakoly

“…<link href="moz-extension://8b922523-7922-435a-ac74-8ddb59e9beaf/skin/s3gt_tooltip_mini.css" rel="stylesheet" type="text/css" > #s3gt_translate_tooltip_mini { display: none !important; }…”
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The effect of using biography in social studies teaching on academic success by Gül Güney, Servet Hali

“…To address this issue, abstract topics outlined in the curriculum must be translated into more tangible forms tailored to student's comprehension levels, which necessitates the utilization of diverse teaching materials. …”
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Evaluating the relative predictive validity of measures of self-referential processing for depressive symptom severity by Ethel Siew Ee Tan, Hong Ming Tan, Kah Vui Fong, Sheryl Yu Xuan Tey, Nikita Rane, Chong Wei Ho, Zhao Yuan Tan, Rachel Jing Min Ong, Chloe Teo, Jerall Yu, Maxine Lee, An Rae Teo, Sin Kee Ong, Xin Ying Lim, Jin Lin Kee, Jussi Keppo, Geoffrey Chern-Yee Tan

“…Hence, understanding the relative contributions of population differences, word lists and calculation methods to these associations with depression, is crucial for translating the SRET into a clinical screening tool. …”
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