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5641
Progress in Therapy Development for Amyotrophic Lateral Sclerosis
Published 2012-01-01“…Reasons will be considered for the frequent failure of preclinical successes to translate into positive clinical outcomes. Finally, this review will explore current trends in experimental therapeutics for ALS with emphasis on the emerging interest in axon guidance signaling pathways as novel targets for pharmacological support of neural cytoskeletal structure and function in order to slow ALS.…”
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5642
Xanthoxyletin blocks the RANK/RANKL signaling pathway to suppress the growth of human pancreatic cancer cells
Published 2023-09-01“…The results revealed a significant (p < 0.05) upregulation of receptor activator of NF-kappaB (RANK), receptor activator of NF-kappaB ligand (RANKL) and osteoprotegerin (OPG) in human pancreatic tissues and cell lines at both transcriptional and translational levels. The administration of pancreatic cancer cells with xanthoxyletin diminished the viability of Capan-2 cells in a concentration-dependent manner and led to a significant decline in RANK, RANKL, and OPG expression. …”
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5643
Higher Education in the Age of Artificial Intelligence
Published 2024-05-01“…However, their curiosity often comes down to using specific AI tools, such as text and image generators, translators, and personal assistants in the educational process. …”
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5644
The convergence of health system resources and health outcome in Central Europe and the Baltic region
Published 2025-12-01“…Therefore, this calls for the need to implement sound reforms in the health systems that could translate increased health system resources into improved health outcomes.…”
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5645
Histoire de la réception et histoire du livre
Published 2024-06-01“…For its demonstration the article develops two case studies devoted to seventeenth- and eighteenth-century England, which closely associate the materiality of texts with the signification of the works: firstly, the different modes of circulation of Shakespeare’s plays and poems (in quarto or folio formats, in collections linking them with other works and other authors, in commonplace books or as quotations in eighteenth-century Shakespearean “Beauties”), and secondly, the multiple forms of appropriation of Don Quixote in England: translations, theatrical adaptations, abridged editions. …”
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5646
The Circulation of Icons in Planetary - Pictures, Popular Culture and Materiality
Published 2015-12-01“…This leads to the development of various strategies, including the creation of a “master style”, a specific visual idiom into which the various icons are translated.…”
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5647
The History of a Genuine Fake Philosophical Treatise (Ḥatatā Zar’a Yā‘eqob and Ḥatatā Walda Ḥeywat). Episode 1: The Time of Discovery. From Being Part of a Collection to Becoming a...
Published 2021-10-01“…In order to show how these texts fit into Giusto d’Urbino’s oeuvre, this article draws on the manuscripts he sent to Antoine d’Abbadie, and analyzes the hitherto unpublished correspondence between the two men. As a linguist and translator, Giusto d’Urbino wanted to make a contribution to Ethiopian studies. …”
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5648
Unsteady Electrohydrodynamic Stagnation Point Flow of Hybrid Nanofluid Past a Convective Heated Stretch/Shrink Sheet
Published 2021-01-01“…The combined set of PDEs is translated into ODEs by including approved similarity transformations. …”
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5649
A Review of Multimedia Projects in Education Design, Producing, and Assessing
Published 2020-12-01“…Barron in 2010 and translated by Khadijeh Aliabadi and Esmail Aslani in 2016 and published by Booka Publisher. …”
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5650
Primary and Secondary Prevention of Obesity
Published 2025-01-01“…Description of the state of knowledge: According to published data, the growing problem of obesity translates into negative consequences in the form of the development of numerous complications associated with it and a shortening of the life expectancy of patients. …”
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5651
Impact de l’apprentissage systémique sur la motivation à apprendre des étudiants dans un contexte d’apprentissage en milieu clinique
Published 2021-03-01“…The data collection concerned 172 students in pre-test and 165 students in post-test, carried out using the “Motived Strategies Learning Questionnaire” in its translated and validated version according to the Vallerand method (1989). …”
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5652
Impact of Time Delay in Perceptual Decision-Making: Neuronal Population Modeling Approach
Published 2017-01-01“…We then apply psychometric function to translate model-predicted ring rates into probabilities that a decision is being made. …”
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5653
“Do look on the other side of the water”: de la politique étrangère de Cromwell à l’égard de la France
Published 2014-07-01“…Under study here is the role played by two actors at the behest of England’s authorities: on the one hand, Edward Sexy, a former New Model Army Agitator who was sent to Bordeaux as a Commonwealth agent in support of the rebellion there and translated the Leveller manifesto The Agreement of the People into English, and on the other hand, William Lockhart, Cromwell’s trusted friend-cum-relative who was appointed special ambassador to France with instructions to strengthen Anglo-French relationships and negotiate with Mazarin for a military alliance against Spain. …”
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5654
Versiones y reescritura en Cants d’Abelone, de Joan Vinyoli
Published 2024-12-01“…Rilke, comparing its two translations into Catalan by Carles Riba and Joan Vinyoli. …”
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5655
From Science to Parliament: How Empathy Became a Political Concept in Finland
Published 2024-12-01“…Empatia, the Finnish word for empathy, became used by politicians in Finland in the second half of the 20th century, just as other translations of the English term took root in their respective contexts. …”
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5656
Molecular mechanisms in liver repair and regeneration: from physiology to therapeutics
Published 2025-02-01“…These trials offer valuable insights into the effectiveness of novel therapies and underscore significant progress in translational research. In conclusion, this review intricately links molecular insights to therapeutic frontiers, systematically charting the trajectory from fundamental physiological mechanisms to innovative clinical applications in liver repair and regeneration.…”
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5657
Comparative acetylome analysis reveals the potential mechanism of high fat diet function in allergic disease
Published 2023-05-01“…Protein acetylation is one of the most important post-translational modifications, and it is involved in regulating multiple body metabolic processes. …”
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5658
Meningkatkan Kesediaan Merawat Orang Dengan HIV/AIDS (ODHA) Pada Perawat Puskesmas Dengan Menggunakan Metode A Brief Intervention
Published 2020-10-01“…Data were collected by using a nursing willingness questionnaire (NWQ) that was translated into Indonesian languages and analyzed using the paired sample t test and independent samples t test. …”
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5659
Mitochondrial-targeted therapies in traumatic brain injury: From bench to bedside
Published 2025-01-01“…Clinical trials and their outcomes are assessed to evaluate the translational potential of mitochondrial-targeted therapies in TBI. …”
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5660
Novel Use of Household Items in Open and Robotic Surgical Skills Resident Education
Published 2019-01-01“…The models will require further evaluation to determine construct validity and to determine how the improvements translate to OR performance. While high-fidelity simulators may continue to be utilized in formal surgical training, residents should be encouraged to supplement their training with innovative homemade models.…”
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