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5521
A truncated variant of the ribosome-associated trigger factor specifically contributes to plant chloroplast ribosome biogenesis
Published 2025-01-01“…Tig2 is widely present in green plants and appears to have acquired an entirely different task than co-translational nascent polypeptide folding. Tig2 deletion results in remarkable leaf developmental defects of cold-exposed Arabidopsis thaliana plants and specific defects in plastidic ribosomes. …”
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5522
Kinematics Analysis of Multi-dimensional Vibration Reduction Construction Vehicle Seat with 2-SPS + SR Suspension
Published 2020-10-01“…Firstly, the degree of freedom analysis of two translations and one rotation of the seat suspension is carried out by using the single-open chain theory. …”
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5523
A Critical Review of the Handbook of Technology and Second Language Teaching and Learning
Published 2020-10-01“…This book has not been translated into Persian and no critical review has been published for it; accordingly, this study sought to both introduce and critically review this book. …”
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5524
Hellenic Language and Thought in Pre-Conquest England
Published 2023-09-01“…The influence of Greek mystical theology would find fuller expression in the translations associated with the court of King Alfred via contact with the Carolingian court, but the seeds for this reception in England may already have been sown. …”
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5525
Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapy
Published 2025-01-01“…Structural studies reveal a region of low sequence homology between these STELLA orthologs that allows mSTELLA but not hSTELLA to bind tightly and cooperatively to the essential histone-binding, linked tandem Tudor domain and plant homeodomain (TTD-PHD) of UHRF1, thus mediating ortholog-specific UHRF1 inhibition. For translating these findings to cancer therapy, we use a lipid nanoparticle (LNP)-mediated mRNA delivery approach in which the short mSTELLA, but not hSTELLA regions are required to reverse cancer-specific DNA hypermethylation and impair colorectal cancer tumorigenicity.…”
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5526
Systematic review of bidirectional interaction between gut microbiome, miRNAs, and human pathologies
Published 2025-02-01“…In vitro, in vivo and in silico analyses were excluded to ensure a strong translational focus on human pathophysiology. Notably, miRNAs, stable and abundant in patients, are emerging as promising biomarkers of microbiome-driven inflammation. …”
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5527
When Ghosts Can Talk: Informant Reality and Ethnographic Policy
Published 2015-06-01“…When informants talk about things like ghosts, witches and magic, there is a tendency to apply analytic strategies which translate these informant statements about the world so they conform to Western understandings about what is possible in the world and what is not. …”
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5528
Skin-Derived Stem Cells for Wound Treatment Using Cultured Epidermal Autografts: Clinical Applications and Challenges
Published 2018-01-01“…We further provide an overview of clinical trial activities in the field and discuss relevant translational and clinical challenges associated with the use of these products.…”
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5529
A Review and Critique of Instructional Models for Physical Education
Published 2020-12-01“…Content failures encompass duplication of content, relative neglect to refer to existing scientific theories, lack of mentioning the integration patterns, the problem of teaching a book during a semester for a two-unit lesson, moderate and weak equation of specialized terminology, and uncertainty to translate book. According to the teacher’s guide books, this book is not recommended to Iranian Physical education teachers.…”
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5530
NEDD4 family E3 ligases in osteoporosis: mechanisms and emerging potential therapeutic targets
Published 2025-01-01“…A central player in these processes is ubiquitin-mediated proteasomal degradation, a crucial post-translational modification system that involves ubiquitin, the ubiquitin-activating enzyme (E1), ubiquitin-conjugating enzyme (E2), ubiquitin ligase (E3), deubiquitinating enzymes, and the proteasome. …”
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5531
Self-assessment policy and perspectives for learning and organizational innovation in postgraduation programs in business administration in brazilian northeast region
Published 2023-12-01“…The conclusion is Self-Assessment can be translated into an Organizational Learning process, in which the analysis of the knowledge produced can lead to changes and innovations in the Programs. …”
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5532
A «new society will come»: C.L.R. James in American Civilisation
Published 2025-01-01“…Although the manuscript was never completed, its historical meaning remains intact for its pervasive vision of the United States and its way of translating Marxian thought into the US culture and politics. …”
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5533
A Critique on the Book Managerial Movements in Public Sector (Past, Present and Future)
Published 2022-07-01“…Numerous books have been written and translated in the field of public administration. Few of these books have gained legitimacy and acceptance among readers. …”
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5534
Dyspareunia is rarely assessed in rodent models of endometriosis and interstitial cystitis/bladder pain syndrome
Published 2025-01-01“…We identify a significant gap in the literature and offer succinct recommendations for future translational research to address this important symptom.…”
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5535
Écrire sur la Shoah avant la Shoah : notes sur Kafka et Levi
Published 2020-06-01“…Even though he did not consider Kafka “quite the same”, the Turin writer accepted the invitation to translate The Trial. In his opinion, even though Kafka was “writing in the first decades of this century, at the turn of the First World War, he foresaw many things”. …”
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5536
Quantum photonics sensing in biosystems
Published 2025-01-01“…Despite these advancements, significant challenges remain in translating these technologies from a controlled laboratory environment to practical, widely applicable devices for diverse biological applications. …”
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5537
LFA-1: A potential key player in microglia-mediated neuroprotection against oxygen-glucose deprivation in vitro.
Published 2025-01-01“…Promising results for neuroprotection by inhibition of integrins with drugs such as natalizumab in animal stroke models have not been translated into clinical practice. Our present study reveals the relevance of a β2 integrin, lymphocyte function-associated antigen-1 (LFA-1), as a potential key player in protecting neuronal cell death after oxygen-glucose deprivation in organotypic hippocampal cell cultures. …”
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5538
Role of Lactate in Inflammatory Processes: Friend or Foe
Published 2022-01-01“…Additionally, various targets, including post-translational modifications, G-protein coupled receptor and transcription factor activation such as NF-κB and HIF-1, allow lactate to modulate signaling pathways that control the expression of cytokines, chemokines, adhesion molecules, and several enzymes associated with immune response and metabolism. …”
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5539
Chemical catalyst manipulating cancer epigenome and transcription
Published 2025-01-01“…Abstract The number and variety of identified histone post-translational modifications (PTMs) are continually increasing. …”
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5540
Elementary Teachers’ Experiences of Implementing Culturally Responsive and Inclusive Education in New York State
Published 2025-01-01“…These findings support the development of school- or districtwide professional learning opportunities to build understanding of the state’s framework and ways to collaboratively translate CRSE values into inclusive teaching.…”
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