4,6-Disubstituted pyrimidine-based microtubule affinity-regulating kinase 4 (MARK4) inhibitors: synthesis, characterization, in-vitro activity and in-silico studies by Ashanul Haque, Khalaf M. Alenezi, Mohd. Saeed Maulana Abdul Rasheed, Md. Ataur Rahman, Saleha Anwar, Shahzaib Ahamad, Dinesh Gupta

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Luvsandanzanzhaltsan (1639–1704) and his Role in the History of Buddhism in Mongolia by Tsymzhit P. Vanchikova

“…Mongolian-language translations of his biography written in Tibetan by Luvsanprinlai, published archival documents on the history of Mongolian monasteries and historical chronicles, publications by D. …”
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The leading “blended” civil medical evacuation operation (MEDEVAC) in unforeseen health emergency. From military use to civil development by Nazzareno Fagoni, Giuseppe Stirparo, Giuseppe Maria Sechi, Andrea Comelli, Gabriele Perotti, Guido Francesco Villa, Alberto Zoli, Marco Botteri

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Small Extracellular Vesicles from Inflamed Adipose Derived Stromal Cells Enhance the NF-κB-Dependent Inflammatory/Catabolic Environment of Osteoarthritis by Carola Cavallo, Giulia Merli, Nicoletta Zini, Stefania D’Adamo, Luca Cattini, Michele Guescini, Brunella Grigolo, Alessandro Di Martino, Spartaco Santi, Rosa Maria Borzì, Giuseppe Filardo

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Sex-specific ultrasound imaging biomarkers of neurodegeneration in a mouse model by Mark B. Russell, Drew P. Locke, Haley M. Adams, Alexander R. Pelley, Rojan Saghian, Rojan Saghian, Alexandre S. Maekawa, Darcie Stapleton, Grace V. Mercer, John G. Sled, John G. Sled, John G. Sled, Lindsay S. Cahill, Lindsay S. Cahill

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A Novel Minimal Invasive Mouse Model of Extracorporeal Circulation by Shuhua Luo, Menglin Tang, Lei Du, Lina Gong, Jin Xu, Youwen Chen, Yabo Wang, Ke Lin, Qi An

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Spinal Cord Stimulation for Refractory Angina Pectoris: Current Status and Future Perspectives, a Narrative Review by Roberto Gazzeri, Jacopo Mosca, Felice Occhigrossi, Marco Mercieri, Marcelo Galarza, Matteo Luigi Giuseppe Leoni

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Enhanced hydrogel loading of quercetin-loaded hollow mesoporous cerium dioxide nanoparticles for skin flap survival by Xiangjun Liu, Yikun Ju, Pu Yang, Naisi Shen, Yunyuan Shao, Anqi Yang, Rui Wu, Lanjie Lei, Bairong Fang

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Non-linear oral bioavailability and clinical pharmacokinetics of high-dose Andrographis paniculata ethanolic extract: relevant dosage implications for COVID-19 treatment by Phanit Songvut, Jaratluck Akanimanee, Tawit Suriyo, Nanthanit Pholphana, Nuchanart Rangkadilok, Duangchit Panomvana, Porranee Puranajoti, Jutamaad Satayavivad

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One size does not fit all: revising traditional paradigms for assessing accuracy of QSAR models used for virtual screening by James Wellnitz, Sankalp Jain, Joshua E. Hochuli, Travis Maxfield, Eugene N. Muratov, Alexander Tropsha, Alexey V. Zakharov

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A novel approach to analyzing the evolution of SARS-CoV-2 based on visualization and clustering of large genetic data compactly represented in operative memory by A. Yu. Palyanov, N. V. Palyanova

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Recent advances in pancreatic α-cell transdifferentiation for diabetes therapy by Yanjiao Li, Yanjiao Li, Jinyu Zhu, Congyang Yue, Siyuan Song, Limin Tian, Yi Wang, Yi Wang, Yi Wang

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Single-cell transcriptome atlas of male mouse pituitary across postnatal life highlighting its stem cell landscape by Silke De Vriendt, Emma Laporte, Berkehür Abaylı, Julie Hoekx, Florian Hermans, Diether Lambrechts, Hugo Vankelecom

“…Finally, we show translatability of mouse atlas-based findings to humans, particularly regarding aging-associated profile. …”
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Lack of HLH in FMF by Ozge Basaran, Erdal Sag, Elif Arslanoglu Aydın, Busra Aydın, Nur Kübra Tasdemir, Elif Celikel, Yagmur Bayındır, Semanur Özdel, Yelda Bilginer, Alexei A Grom, Seza Ozen

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Artificial intelligence empowered voice generation for amyotrophic lateral sclerosis patients by Stefano Regondi, Giordana Donvito, Emanuele Frontoni, Milutin Kostovic, Fabio Minazzi, Sébastien Bratières, Massimiliano Filosto, Raffaele Pugliese

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Digital health technologies and self-efficacy in Parkinson’s: a scoping review by Victoria Allgar, Edward Meinert, Camille B Carroll, Andrew Michael Hall

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Chromosome-level genome reference of the Caucasian dwarf goby Knipowitschia cf. caucasica, a new alien Gobiidae invading the River Rhine by Schoenle, Alexandra, Guiglielmoni, Nadège, Mainz, Tobias, Greve, Carola, Hamadou, Alexander Ben, Heermann, Lisa, Borcherding, Jost, Waldvogel, Ann-Marie

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Pharmacological Characterization of the Mechanisms Involved in Delayed Calcium Deregulation in SH-SY5Y Cells Challenged with Methadone by Sergio Perez-Alvarez, Maria E. Solesio, Maria D. Cuenca-Lopez, Raquel M. Melero-Fernández de Mera, Carlos Villalobos, Hanna Kmita, Maria F. Galindo, Joaquin Jordán

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Squamous Cell Carcinomas of the Skin Explore Angiogenesis-Independent Mechanisms of Tumour Vascularization by Ievgenia Pastushenko, Tamara Gracia-Cazaña, Sandra Vicente-Arregui, Gert G. Van den Eynden, Mariano Ara, Peter B. Vermeulen, Franciso José Carapeto, Steven J. Van Laere

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Implication of tumor morphology and MRI characteristics on the accuracy of automated versus human segmentation of GBM areas by Valeria Cerina, Chiara Benedetta Rui, Andrea Di Cristofori, Davide Ferlito, Giorgio Carrabba, Carlo Giussani, Gianpaolo Basso, Elisabetta De Bernardi

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