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4441
Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells
Published 2025-01-01“…In conclusion, small animal studies have demonstrated the feasibility of high-throughput approaches for the discovery of pMHC epitopes recognised by directly alloreactive T cells. Translating this approach to the human setting is achievable and will yield both critical insights into the fundamental basis of alloreactivity and powerful tools for immune monitoring in transplantation.…”
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4442
Exploring Current Evidence on the Past, the Present, and the Future of the Heart Team: A Narrative Review
Published 2020-01-01“…Finally, these facts should be translated into better cardiovascular outcomes and a lower psychological distress among Team participants. …”
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4443
Transcriptional and Posttranscriptional Regulations of the HLA-G Gene
Published 2014-01-01“…The HLA-G promoter region is different from the classical class I promoters, mainly because (i) it lacks regulatory responsive elements for IFN-γ and NF-κB, (ii) the proximal promoter region (within 200 bases from the first translated ATG) does not mediate transactivation by the principal HLA class I transactivation mechanisms, and (iii) the presence of identified alternative regulatory elements (heat shock, progesterone and hypoxia-responsive elements) and unidentified responsive elements for IL-10, glucocorticoids, and other transcription factors is evident. …”
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4444
Are Ancient Durum Wheats Less Toxic to Celiac Patients? A Study of α-Gliadin from Graziella Ra and Kamut
Published 2012-01-01“…For all accessions, a few α-gliadin alleles were also cloned, sequenced and translated into aminoacid sequences. Several aminoacid substitutions or deletions were detected in p31–49, DQ2-Glia-α1 and DQ2-Glia-α2 epitopes, nevertheless, ELISA constantly showed antibody-antigen positive reactions which led us to suggest that mAbs binding was not apparently affected by polymorphisms. …”
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4445
Approbation of the mechanism of economic reliability on the example of an industrial enterprise
Published 2023-02-01“…Absolute indicators for the main processes of an industrial enterprise have been translated into dimensionless ones, and partial indicators of desirability have been found. …”
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4446
Professionals’ perception on nutritional care of adult patients in comprehensive specialized hospitals of East Wollega Zone, Ethiopia
Published 2025-01-01“…The data were transcribed verbatim and translated into English. A thematic analysis was used to analyze the data. …”
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4447
Curcumin Is an Iconic Ligand for Detecting Environmental Pollutants
Published 2022-01-01“…This review will afford references for future studies and enable researchers to translate the lab concepts into industrial products.…”
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4448
Enhancing counterfeit RFID tag classification through distance based cognitive risk control
Published 2025-02-01“…Concurrently, in comparison to traditional twenty-eight and seven features, the adoption of one-hundred-and-four features translates to an enhancement in classification accuracy by roughly 4.3% and 5.3%, respectively. …”
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4449
Vaccines for cancer interception in familial adenomatous polyposis
Published 2025-01-01“…This review will examine the current state of vaccines directed against FAP lesions and highlight the challenges and opportunities of translating vaccines for cancer interception in FAP to the clinic.…”
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4450
Targeting protein kinase C-α prolongs survival and restores liver function in sepsis: Evidence from preclinical models
Published 2025-02-01“…Here, it reduced plasma bile acids and related inflammation in those patients, opening a translational avenue for therapeutics in sepsis. Conclusively, our research underscores the significance of PKCα in controlling excretory liver function during inflammation. …”
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4451
Blueprint for a high-performance biomaterial: full-length spider dragline silk genes.
Published 2007-06-01“…Each gene includes a single enormous exon (>9000 base pairs) that translates into a highly repetitive polypeptide. Patterns of variation among sequence repeats at the amino acid and nucleotide levels indicate that the interaction of selection, intergenic recombination, and intragenic recombination governs the evolution of these highly unusual, modular proteins. …”
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4452
State of the art progress of Evolvulus alsinoides in pharmacological activity and plant tissue culture: A potent Chinese medicinal plant
Published 2025-03-01“…Nevertheless, thorough clinical trials and translational research are required to bridge the gap between conventional knowledge and current medical uses. …”
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4453
Unit commitment in microgrid systems using artificial intelligence techniques
Published 2024-08-01“…Importantly, E-HPSO–SA demonstrated a substantial cost advantage over PSO and E-HPSO–ACO, exceeding them by approximately 57.4% and 52.5%, respectively. This translates to a significant improvement in cost-efficiency, ensuring a reliable and sustainable power supply while effectively mitigating rising expenses. …”
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4454
Concurrent Viewing of H&E and Multiplex Immunohistochemistry in Clinical Specimens
Published 2025-01-01“…<b>Methods:</b> We have now simplified the microscope system to a single camera and increased the IHC multiplexing to four biomarkers using translational assays. The color camera used in this approach also enabled multispectral imaging, similar to monochrome cameras. …”
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4455
A New Approach for Solving Rub-Impact Dynamic Characteristics of Shrouded Blades Based on Macroslip Friction Model
Published 2020-01-01“…By means of the harmonic balance method, the friction force and the normal pressure are translated into the equivalent stiffness and the equivalent damping. …”
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4456
Cardiovascular risk profiling among South Asian adults in Hong Kong: a latent class analysis
Published 2025-01-01“…The heavy burden on obesity especially in women, lifestyle and psychological risks especially in men, and low overall physical activity level may be translated into a tremendous cardiovascular disease burden in the forthcoming decades, in particular among Pakistani and Nepalese as well as the socioeconomically disadvantaged.…”
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4457
Variants of the Sliding Mode Control in Presence of External Disturbance for Quadrotor
Published 2020-01-01“…Simulations are presented to verify that the proposed scheme is effective with Hurwitz stability for both translational and rotational parts of the quadrotor.…”
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4458
Perspectives of push-pull-mooring effects on a desire for switching to alternative crops among tobacco farmers in Thailand: A qualitative study
Published 2024-01-01“…Data were recorded and transcribed verbatim in Thai and subsequently translated into English. A deductive content analysis applied the Push-Pull-Mooring (PPM) framework, contextualizing factors for the transition among tobacco farmers. …”
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4459
Perceived causes of cancer in a rural community of Ethiopia: a qualitative study
Published 2024-12-01“…Results Across respondent categories and data collection methods, respondents described cancer or nekersa, which translates as ‘an illness that cannot be cured’, as serious and fatal. …”
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4460
Understanding HIV care providers’ support for tobacco cessation among people living with HIV in Western Kenya: a formative qualitative study
Published 2024-04-01“…The interviews and discussions were audio-recorded, and audio files were transcribed and, when necessary, translated into English for coding and analysis.Results PLHIV rarely disclose or are screened for tobacco use unless a complaint or clinical finding prompts a provider. …”
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