Driving Innovation to Support Pupils with SEND Through Co-Production in Education and Research: Participatory Action Research with 22q11.2 Deletion Syndrome Families in England by Michelle Jayman, Sophie Edmonds, Maria Gudbrandsen

“…However, evidence suggests pupils’ learning and wellbeing needs are often missed or unmet and legislation designed to increase families’ decision-making in education provision has not been translated into practice. The current participatory action research study investigated the perceptions and experiences of a specific population of SEND pupils in mainstream schooling—CYP with 22q11.2 deletion syndrome (22q). …”
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Occupational Risks in Occupational Therapy Service Learning: A Single-Site “Fear Factor” Study in South Africa by Deshini Naidoo, Pragashnie Govender, Stephanie Nicole Naidoo, Naledi Ngubane, Zamankosi Nkosi, Aziza Mulla

“…These insights into the perceived occupational risk factors can be translated into actionable strategies to improve the preparation of health science students for service-learning, including coping skills to deal with the demands of service-learning.…”
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Form destabilization: Between reality and projection by Mojsilović Mila

“…In the plane of architectural production, the neutral framework of universal space for the production of diversity is translated into a digital one. A new definition of values and criteria, based on variability and potentiality, serves to introduce a metanarrative of multiplicity in terms of manifold ways of decoding the world and reality. …”
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Optimization of Distillation Conditions for Improved Recovery of Phthalides from Celery (Apium graveolens L.) Seeds by Adam Kokotkiewicz, Anna Badura, Żaneta Tabaczyńska, Andżelika Lorenc, Adam Buciński, Maria Luczkiewicz

“…The change of distillation mode from HD to SDE significantly increased the oil yield of whole seeds (from 2.8 to 5.8% for 6 h processing) while maintaining its high phthalide content (62.5%), which translated to an increase in the total phthalide yield from 19.4 to 36.0 g/kg.…”
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An epigenetic memory at the CYP1A gene in cancer-resistant, pollution-adapted killifish by Samantha Carrothers, Rafael Trevisan, Nishad Jayasundara, Nicole Pelletier, Emma Weeks, Joel N. Meyer, Richard Di Giulio, Caren Weinhouse

“…We detected a bivalent domain in the CYP1A promoter enhancer comprising both activating and repressive histone post-translational modifications. Activating modifications, relative to repressive ones, showed greater increases in response to PAH in sensitive embryos, relative to tolerant, consistent with greater gene activation. …”
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Comparative Study of Ectopic Lymphoid Aggregates in Sheep and Murine Models of Bleomycin-Induced Pulmonary Fibrosis by Udari Eshani Perera, Louise Organ, Simon G. Royce, Chrishan S. Samuel, Habtamu B. Derseh, Sasika N. V. Dewage, Emmanuel Koumoundouros, Andrew Stent, Kenneth J. Snibson

“…This study evaluated the histopathological and inflammatory components of bleomycin-induced pulmonary fibrosis in mouse and sheep models, in terms of their ability to translate to the human IPF. Merino sheep (n = 8) were bronchoscopically administered with two bleomycin infusions, two weeks apart, into a caudal lung segment, with a saline (control) administered into a caudal segment in the opposite lung. …”
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Human Fat-Derived Mesenchymal Stem Cells Xenogenically Implanted in a Rat Model Show Enhanced New Bone Formation in Maxillary Alveolar Tooth Defects by Andrew Wofford, Austin Bow, Steven Newby, Seth Brooks, Rachel Rodriguez, Tom Masi, Stacy Stephenson, Jack Gotcher, David E. Anderson, Josh Campbell, Madhu Dhar

“…Gelfoam®, a commonly used clinical biomaterial, can serve as a scaffold to deliver and maintain MSCs to the defect site. Translating this strategy to preclinical animal models provides hope for bone tissue engineering.…”
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Towards the praxis of a sustainable knowledge‑based economy by Agnieszka Klimska

“…Implementation of the preferred directions of development, requires not so much efficient, but proper management, i.e. one which would translate itself onto the plane of decision-making and, subsequently, that of application. …”
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A novel protein encoded by porcine circANKRD17 activates the PPAR pathway to regulate intramuscular fat metabolism by Xiao He, Fang Xie, Ying Nie, Xuefeng Wang, Junyi Luo, Ting Chen, Qianyun Xi, Yongliang Zhang, Jiajie Sun

“…In addition, we discovered that circANKRD17 has an open reading frame and can be translated into a novel 571-amino-acid protein that promotes lipid metabolism. …”
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The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons by Catherine Schaefers, Simone Rothmiller, Horst Thiermann, Theo Rein, Annette Schmidt

“…However, these often apply viral vectors, feeder cells, or antibiotics to generate hiPSC and MNs, limiting their translational potential. In this study, a virus-, feeder-, and antibiotic-free method was used for reprogramming hiPSC, which were maintained in culture medium produced under clinical good manufacturing practice. …”
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Re-Calibrating Network by Refining Initial Features Through Generative Gradient Regularization by Naim Reza, Ho Yub Jung

“…Notably, this refinement in features translates to improved generalization and the proposed method also eliminates the necessity of total retraining of the target network. …”
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Ceramic Hollow Fibre Constructs for Continuous Perfusion and Cell Harvest from 3D Hematopoietic Organoids by Mark C. Allenby, Asma Tahlawi, José C. F. Morais, Kang Li, Nicki Panoskaltsis, Athanasios Mantalaris

“…Herein, we propose HFs to improve 3D cell culture nutrient and metabolite diffusion, increase culture volume and cell density, and continuously harvest products for translational cell therapy biomanufacturing protocols.…”
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Injectable Hierarchical Bioactive Hydrogels with Fibroblast Growth Factor 21/Edaravone/Caffeic Acid Asynchronous Delivery for Treating Parkinson's Disease by Junpeng Xu, Peng Dai, Chen Zhang, Na Dong, Caiyan Li, Chonghui Tang, Zhihao Jin, Shih‐Ho Lin, Luyang Ye, Tianmiao Sun, Yukai Jin, Fenzan Wu, Lihua Luo, Ping Wu, Shengcun Li, Xiaokun Li, Shan‐hui Hsu, Dawei Jiang, Zhouguang Wang

“…The combination of clinical drugs targeting different symptoms with smart hydrogels to achieve asynchronous releases is highly translational and challenging. Here, a hierarchical bioactive hydrogel (OACDP) is designed with asynchronous release based on PD pathology. …”
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Establishment and characterization of ovarian clear cell carcinoma patient-derived xenografts by Joseph J. Caumanns, Shang Li, Gert J. Meersma, Evelien W. Duiker, Ate G. J. van der Zee, G. Bea A. Wisman, Steven de Jong

“…In conclusion, the high phenotypic and molecular similarity allows the established PDXs to serve as potential preclinical models for future translational research of OCCC.…”
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SDG-enabled decarbonisation transport pathways for mid-sized Indian cities by Darshini Mahadevia, Saumya Lathia, Chandrima Mukhopadhyay

“…This paper argues that (1) climate mitigation measures in countries like India – with rising income inequality and high social diversity in caste, religion and region – need a tailored assessment approach, (2) carefully mediating climate mitigation measures – like deep decarbonisation – at the local level is crucial to enable transformative change required to meet the Paris Agreement and the UN Agenda 2030, (3) enabling ‘just’ deep decarbonisation or SDG-enabled decarbonisation at the local level requires addressing unmet needs of the vulnerable population even at the cost of increased emissions, and (4) sector-specific decarbonisation strategies at the national level must be translated into the local area’s social, economic, environmental and institutional realities. …”
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The Canadian Registry for Pulmonary Fibrosis: Design and Rationale of a National Pulmonary Fibrosis Registry by Christopher J. Ryerson, Benjamin Tan, Charlene D. Fell, Hélène Manganas, Shane Shapera, Shikha Mittoo, Mohsen Sadatsafavi, Teresa To, Andrea Gershon, Jolene H. Fisher, Kerri A. Johannson, Nathan Hambly, Nasreen Khalil, Theodore K. Marras, Julie Morisset, Pearce G. Wilcox, Andrew J. Halayko, Mohammad Adil Khan, Martin Kolb

“…As the largest and most comprehensive cohort of Canadian ILD patients, CARE-PF establishes a network for future clinical research and early phase clinical trials and provides a platform for translational and basic science research.…”
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Circulating MicroRNAs in Elderly Type 2 Diabetic Patients by Giuseppina Catanzaro, Zein Mersini Besharat, Martina Chiacchiarini, Luana Abballe, Claudia Sabato, Alessandra Vacca, Paola Borgiani, Francesco Dotta, Manfredi Tesauro, Agnese Po, Elisabetta Ferretti

“…Intra- and intergroup comparison of miRNA profiles pinpointed three miRNAs that correlated with responses to sitagliptin: miR-378, which is a candidate biomarker of resistance to this DPP-IVi, and miR-126-3p and miR-223, which are associated with positive responses to the drug. The translational implications are as immediate as evident, with the possibility to develop noninvasive diagnostic tools to predict drug response and development of chronic complications.…”
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Explanation of tourism capabilities and management for geosites on based assessment method of geodiversity sites by SOMAIE Jahantigh, Amir Karam, Ezatollah Ghanavati

“…<link href="moz-extension://e82f9c05-bf9c-4e25-87b0-684d37ab5915/skin/s3gt_tooltip_mini.css" rel="stylesheet" type="text/css" > #s3gt_translate_tooltip_mini { display: none !important; }…”
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Operational Risk Assessment for the Pollination Service with Apis mellifera Bees in Cashew Crops in Vichada, Colombia by Lizeth Castro Mercado, Juan José Bravo Bastidas, Juan Carlos Osorio Gómez

“…This substantial value is of great significance to the beekeeping sector, translating to a loss of $27.3 per hectare per year and directly impacting the estimated $437824 loss in the cashew sector. …”
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Artificial intelligence in higher education: problems, opportunities, risks by Renata R. Gasanova, Ekaterina A. Romanova

“…There are opportunities to optimize the learning process using AI, such as assessing the level of knowledge of students according to predetermined criteria, organizing and conducting tests and exams, ability to get rid of routine work, translating and voicing any text. Conclusion. It is summarized that the most promising direction for application of AI technologies in higher education is an additional education, which is organized primarily for acquisition of specific knowledge and skills by reducing the time spent searching for literature, scientific reviews, setting specific tasks and problems, organizing communication, etc.…”
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