Development of a cell-penetrating peptide-based nanocomplex for long-term delivery of intact mitochondrial DNA into epithelial cells by Kyrie Wilson, Charles Holjencin, Hwaran Lee, Balasubramaniam Annamalai, Masaaki Ishii, Jeremy L. Gilbert, Andrew Jakymiw, Bärbel Rohrer

“…Gene therapy approaches for mitochondrial DNA (mtDNA)-associated damage/diseases have thus far been limited, and despite advancements in single gene therapy for mtDNA mutations and progress in mitochondrial transplantation, no method exists for restoring the entire mtDNA molecule in a clinically translatable manner. Here, we present for the first time a strategy to deliver an exogenous, fully intact, and healthy mtDNA template into cells to correct endogenous mtDNA mutations and deletions, with the potential to be developed into an efficient pan-therapy for inherited and/or acquired mtDNA disorders. …”
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Biblical Turns of Phrase, Repetition and Circularity in Oscar Wilde’s Salome by Sébastien Salbayre

“…Written in French and translated into English by Lord Alfred Douglas with the help of the author himself at a time when novelists, poets and playwrights celebrated artifice and started revolutionising the forms of their art, Oscar Wilde’s Salome (1893) created a new language and located radical representational possibilities. …”
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Cognitive Emotional Regulation Model in Human-Robot Interaction by Xin Liu, Lun Xie, Anqi Liu, Dan Li

“…The input facial expression was translated into external energy by expression-emotion mapping. …”
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Novel Visualization of Building Earthquake Response Recorded by a Dense Network of Sensors by Lichiel Cruz, Maria I. Todorovska, Mihailo D. Trifunac, Alimu Aihemaiti, Guoliang Lin, Jianwen Cui

“…The animations provide invaluable insight into the 3D structural response of the building as a whole, including wave propagation through the structure and the interplay between translations and rotations, which will be useful for testing existing and developing new methods for structural health monitoring of buildings and for the further development of building design codes. …”
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Evolutionary analysis of the DHHCs in Saccharinae by Hao Wen, Xinyu Liu, Xueting Zhao, Tingting Zhao, Cuilian Feng, Hailong Chang, Jungang Wang, Jishan Lin

“…Abstract The DHHC domain genes are crucial for protein lipid modification, a key post-translational modification influencing membrane targeting, subcellular trafficking, and protein function. …”
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Molecular genetic methods for intestinal microbiome investigation by O. L. Kardymon, A. V. Kudryavtseva

“…Results of scientific activity is gradually translated into clinical practice and become the standard for diagnosis and a basis for development of new treatment methods.…”
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Barriers to and impacts of hepatitis C treatment among people who inject drugs in Kenya: A qualitative study. by Hannah N Manley, Lindsey R Riback, Mercy Nyakowa, Matthew J Akiyama, Peter Cherutich, John Lizcano, Ann Kurth, Abbe Muller

“…Using Rhodes' Risk Environment Framework to guide our work, we conducted semi-structured interviews with 35 PWID who received HCV treatment in methadone clinics and drop-in-centers (DICs) in Nairobi and coastal Kenya supported by peer case managers from August to September 2019. Translated and transcribed interviews were analyzed thematically. …”
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Exploring the End-of-Life Experiences of Advanced Cancer Patients from India by Maria Wajid, Eslavath Rajkumar, J Romate

“…The semi-structured interviews with the participants were audio-recorded, transcribed, and translated. Identification of patterns and commonalities in the dataset helped generate codes. …”
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Identification of Type VI Collagen Synthesizing Cells in Human Diabetic Glomerulosclerosis Using Renal Biopsy Sections by Mohammed Shawkat Razzaque, Takehiko Koji, Takashi Harada, Takashi Taguchi

“…Type VI collagen‐specific oligonucleotide probes and monoclonal antibody were used to assess the relative expression of mRNA for \alpha1 (VI) chain and its translated protein in paraffin‐embedded renal biopsy sections of DN. …”
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Seaweed and yeast extracts as sustainable phytostimulant to boost secondary metabolism of apricot fruits by Noemi Gatti, Moez Maghrebi, Graziella Serio, Carla Gentile, Victor V. Bunea, Ivano Vigliante, Camille Boitte, Christian Garabello, Valeria Contartese, Cinzia M. Bertea, Giuseppe Mannino

“…These metabolic enhancements translated into significantly increased total antioxidant activity, particularly evident in the peel samples. …”
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Key Role of Phosphorylation in Small Heat Shock Protein Regulation via Oligomeric Disaggregation and Functional Activation by Zachary B. Sluzala, Angelina Hamati, Patrice E. Fort

“…Phosphorylation, a key post-translational modification (PTM), plays a dynamic role in regulating sHSP structure, oligomeric state, stability, and chaperone function. …”
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When Analysts turn into Boxers: An Introduction to Pre-Sales Requirements Engineering by Christoph Oemig

“…The latter are needed to translate the customers’ needs to features, to efforts, and eventually to costs. …”
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Investigating the Possibility to Reduce the Residual Stress Level in 2.5D Cutting Using Titanium Coated Carbide Ball End Mill by N. Masmiati, H. S. Chan, Ahmed A. D. Sarhan, M. A. Hassan, M. Hamdi

“…It is widely used in cutting 2.5D profiles such as point-to-point, contouring, and pocketing operations. 2.5D machining possesses the capability to translate in all 3 axes but can perform the cutting operation in only 2 of the 3 axes at a time. …”
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The nonlinear cysteine redox dynamics in the i-space: A proteoform-centric theory of redox regulation by James N. Cobley, Panagiotis N. Chatzinikolaou, Cameron A. Schmidt

“…The post-translational redox regulation of protein function by cysteine oxidation controls diverse biological processes, from cell division to death. …”
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Current Status of Treatment of Spinal and Bulbar Muscular Atrophy by Fumiaki Tanaka, Masahisa Katsuno, Haruhiko Banno, Keisuke Suzuki, Hiroaki Adachi, Gen Sobue

“…Since ligand-induced nuclear translocation of mutant AR has been shown to be a critical step in motor neuron degeneration in SBMA, androgen deprivation therapies using leuprorelin and dutasteride have been developed and translated into clinical trials. Although the results of these trials are inconclusive, renewed clinical trials with more sophisticated design might prove the effectiveness of hormonal intervention in the near future. …”
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Contemporary Evaluation and Management of the Diabetic Foot by Bauer E. Sumpio

“…While these, increasingly expensive, therapies have shown promising results in clinical trials, the results have yet to be translated into widespread clinical practice leaving a huge scope for further research in this field.…”
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The Adaptive Neuroplasticity Hypothesis of Behavioral Maintenance by Janey C. Peterson

“…In this paper we will: (1) describe the enormous potential for neuroplasticity in older adults; (2) review stress and depression as examples of maladaptive neuroplasticity; (3) describe an example of adaptive neuroplasticity achieved with a behavioral intervention that induced positive affect in people with CHD; and (4) discuss implications for future work in bench to bedside translational research.…”
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Effect of Superabsorbent Polymer (SAP) Internal Curing Agent on Carbonation Resistance and Hydration Performance of Cement Concrete by Jieting Xu, Xiao Qin, Zhenying Huang, Yongkang Lin, Ben Li, Zhengzhuan Xie

“…The results showed that (i) when the particle size and dosage of SAP were 100 mesh and 0.200%, the carbonation depth of internally cured concrete was only 56.5% of the control group on day 28; (ii) the Ca(OH)2 absorption peak area of SAP-concrete in the FTIR spectra could be increased by 3.38 times than that of the control group, and more C2S and C3S were translated into Ca(OH)2, which helped to improve the hydration degree of cement concrete; (iii) the hydration products of day 56 were increased significantly and the remaining pores formed by SAP gels were gradually filled by hydration products, which enhanced the compactness and carbonation resistance of cement concrete.…”
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Adjuvant Radiochemotherapy with a 23-Month Overall Survival Time in a Patient after a Surgery due to Splenic Hemangiosarcoma Rupture: A Case Report with the Literature Review by M. Bilski, D. Surdyka, I. Paśnik, M. Bilska, P. Cisek, P. Korona, J. Szumiło, L. Grzybowska-Szatkowska

“…Postoperative radiotherapy may increase local disease control, especially after nonradical operation, but this does not translate into improvement in overall survival time of these patients. …”
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The role of risk attitudes in shaping digital privacy preferences: evidence from a large-scale survey by Jing Chen, Manling Zhang, Mengyao Guo, Ze Gao

“…In addition, we observe that while these concerns translate into higher non-disclosure actions, the privacy paradox persists regardless of individuals’ risk attitudes. …”
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