Cardiovascular Disease, Single Nucleotide Polymorphisms; and the Renin Angiotensin System: Is There a MicroRNA Connection? by Terry S. Elton, Sarah E. Sansom, Mickey M. Martin

“…MicroRNAs (miRNAs) are a family of small, ∼21-nucleotide long, and nonprotein-coding RNAs that recognize target mRNAs through partial complementary elements in the 3-untranslated region (3-UTR) of mRNAs and inhibit gene expression by targeting mRNAs for translational repression or destabilization. Since miRNA SNPs (miRSNPs) can create, destroy, or modify miRNA binding sites, this review focuses on the hypothesis that transcribed target SNPs harbored in RAS mRNAs, that alter miRNA gene regulation and consequently protein expression, may contribute to cardiovascular disease susceptibility.…”
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SEC-MX: an approach to systematically study the interplay between protein assembly states and phosphorylation by Ella Doron-Mandel, Benjamin J. Bokor, Yanzhe Ma, Lena A. Street, Lauren C. Tang, Ahmed A. Abdou, Neel H. Shah, George Rosenberger, Marko Jovanovic

“…Abstract A protein’s molecular interactions and post-translational modifications (PTMs), such as phosphorylation, can be co-dependent and reciprocally co-regulate each other. …”
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A Transient Dynamic Model of Brake Corner and Subsystems for Brake Creep Groan Analysis by Dejian Meng, Lijun Zhang, Jie Xu, Zhuoping Yu

“…It is also found that the lining and caliper not only have stick-slip motion in each coordinate direction but also have translational and torsional movements in plane, which relate to the microscopic sticking and slipping, friction coefficient, and forces, as well as the contact status at the friction interface.…”
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Beyond Humanoid Prosthetic Hands: Modular Terminal Devices That Improve User Performance by Digby Chappell, Barry Mulvey, Shehara Perera, Fernando Bello, Petar Kormushev, Nicolas Rojas

“…Case studies with two end users demonstrate the translational benefits of this research. We found that special attention should be paid to monitoring end-user task load to ensure positive rehabilitation outcomes.…”
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Environment, Leptin Sensitivity, and Hypothalamic Plasticity by Marco Mainardi, Tommaso Pizzorusso, Margherita Maffei

“…Use of these protocols can, in turn, be exploited to isolate key molecules with translational potential. In the present review, we summarize present knowledge about the mechanisms of plasticity induced by the environment in the ARC. …”
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LANGUAGE FUNCTION ACQUISITION OF THREE-YEAR-OLD CHILDREN IN URBAN EDUCATED FAMILY ENVIRONMENT by Anita Dewi Kurniasari, Yakub Nasucha, Ali Imron Al-Ma’Ruf

“…Data analysis is performed using the translational, phonetic, and referential identity methods. …”
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Reforming Real Estate Valuation for Financial Auditors With AI: An In-Depth Exploration of Current Methods and Future Directions by Silviu-Ionut BABTAN

“…The author starts by investigating traditional valuation methods' limitations, such as data constraints and subjectivity, and presents how these AI techniques, which are translated in property valuation field as automated valuation methods, tackle these challenges. …”
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Fibromyalgia Detection and Diagnosis: A Systematic Review of Data-Driven Approaches and Clinical Implications by Anirudh Atmakuru, Subrata Chakraborty, Massimo Salvi, Oliver Faust, Prabal Datta Barua, Makiko Kobayashi, Ru San Tan, Filippo Molinari, Abdul Hafeez-Baig, U. Rajendra Acharya

“…In this systematic review, we explore the role of artificial intelligence in understanding FMS pathophysiology, discuss the present limitations, and shed light on future research avenues, aiming to translate findings into improved clinical outcomes.…”
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BenthicNet: A global compilation of seafloor images for deep learning applications by Scott C. Lowe, Benjamin Misiuk, Isaac Xu, Shakhboz Abdulazizov, Amit R. Baroi, Alex C. Bastos, Merlin Best, Vicki Ferrini, Ariell Friedman, Deborah Hart, Ove Hoegh-Guldberg, Daniel Ierodiaconou, Julia Mackin-McLaughlin, Kathryn Markey, Pedro S. Menandro, Jacquomo Monk, Shreya Nemani, John O’Brien, Elizabeth Oh, Luba Y. Reshitnyk, Katleen Robert, Chris M. Roelfsema, Jessica A. Sameoto, Alexandre C. G. Schimel, Jordan A. Thomson, Brittany R. Wilson, Melisa C. Wong, Craig J. Brown, Thomas Trappenberg

“…These are accompanied by 3.1 million annotations translated to the CATAMI scheme, which span 190,000 of the images. …”
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Critical Aspects of Clinical Trial Design for Novel Cell and Gene Therapies by Zinovia Kefalopoulou, Iciar Aviles-Olmos, Thomas Foltynie

“…Beyond the provision of symptomatic efficacy and safety data, it also remains to be identified whether the possibilities offered by stem cell and gene therapy technological advances might translate to meaningful neuroprotection and/or disease-modifying effects or alleviate the nonmotor aspects of PD and thus offer additional benefits beyond those achieved through conventional pharmacotherapy or deep brain stimulation (DBS).…”
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Exploring Novel Non-Operative Treatments for Osteoarthritis: An Examination of Innovative Therapies by Piotr Robert Bakuła, Kamila Jałocha, Joanna Zygadło

“…Despite significant progress, challenges such as translational hurdles, cost barriers, and long-term efficacy require further investigation. …”
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Mechanisms of Inflammation in Proliferative Vitreoretinopathy: From Bench to Bedside by Stavros N. Moysidis, Aristomenis Thanos, Demetrios G. Vavvas

“…Here we review inflammatory and other mechanisms involved in the pathogenesis of PVR, we highlight important clinical trials, and we discuss how findings at the bench have the potential to be translated to the bedside.…”
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The promising role of nanopore sequencing in cancer diagnostics and treatment by Xinming Su, Qingyuan Lin, Bin Liu, Chuntao Zhou, Liuyi Lu, Zihao Lin, Jiahua Si, Yuemin Ding, Shiwei Duan

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Mitigating bias in AI mortality predictions for minority populations: a transfer learning approach by Tianshu Gu, Wensen Pan, Jing Yu, Guang Ji, Xia Meng, Yongjun Wang, Minghui Li

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A New Antibody–Cytokine Construct Targeting Natural Killer Cells: An Immunotherapeutic Approach to Chronic Lymphocytic Leukemia by Michela Flego, Mauro Andreotti, Francesca Romana Mauro, Maria Beatrice Arasi, Silvia Zamboni, Zuleika Michelini, Sara Pepe, Clementina Maria Galluzzo, Roberta Amici, Diego Moricoli, Chiara Mazzei, Alessandro Ascione, Alessandra Mallano

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Comparison of the epidemiological characteristics of mycoplasma pneumoniae infections among children during two epidemics in Wuhan from 2018 to 2024 by Jieyu Mao, Zhili Niu, Mengling Liu, Liangyu Li, Haiyue Zhang, Ruiyun Li, Pingan Zhang, Xiaojun Wu

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Fish Scale-Derived Scaffolds for Culturing Human Corneal Endothelial Cells by Mohit Parekh, Bert Van den Bogerd, Nadia Zakaria, Diego Ponzin, Stefano Ferrari

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Pirfenidone regulates seizures through the HMGB1/TLR4 axis to improve cognitive functions and modulate oxidative stress and neurotransmitters in PTZ-induced kindling in mice by Mansi Dahalia, Sparsh Gupta, Haya Majid, Divya Vohora, Nidhi

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Factors, characteristics and influences of the changes of muscle activation patterns for patients with knee osteoarthritis: a review by Shizhong Liu, Zuyu Du, Le Song, Haoyue Liu, Clarence Augustine T. H. Tee, Huanyu Liu, Yuan Liu

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Early Detection of Microvascular Changes in Patients with Diabetes Mellitus without and with Diabetic Retinopathy: Comparison between Different Swept-Source OCT-A Instruments by Stela Vujosevic, Caterina Toma, Edoardo Villani, Valentina Gatti, Marco Brambilla, Andrea Muraca, Maria Chantal Ponziani, Gianluca Aimaretti, Alessandro Nuzzo, Paolo Nucci, Stefano De Cilla’

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