Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

“…Abstract Background Succinic semialdehyde dehydrogenase deficiency (SSADHD) represents a model neurometabolic disease at the fulcrum of translational research within the Boston Children’s Hospital Intellectual and Developmental Disabilities Research Centers (IDDRC), including the NIH-sponsored natural history study of clinical, neurophysiological, neuroimaging, and molecular markers, patient-derived induced pluripotent stem cells (iPSC) characterization, and development of a murine model for tightly regulated, cell-specific gene therapy. …”
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Stuck in the middle with you: the role of senior leaders as third space professionals by Alison Purvis, Beth Fielding-Lloyd, Melissa Jacobi, Dave Thornley, Nick Woolley

“… This collaborative opinion piece offers the perspective that senior leaders must move beyond their traditional places within the academic or professional services spaces to act as hybrid professionals or translators. We take five perspectives as senior leaders and build a collective opinion of our view of the role of senior leaders as third space professionals. …”
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Post-processing methods for delay embedding and feature scaling of reservoir computers by Jonnel Jaurigue, Joshua Robertson, Antonio Hurtado, Lina Jaurigue, Kathy Lüdge

“…For experimentalists, all our post-processing methods can be translated to readout data sampled from physical reservoirs, which we demonstrate using readout data from an experimentally-realised laser reservoir system.…”
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Helminth Parasites and the Modulation of Joint Inflammation by Chelsea E. Matisz, Jason J. McDougall, Keith A. Sharkey, Derek M. McKay

“…Helminth parasites are accomplished masters at modifying their hosts' immune activity, and so attention has focused on rodent-helminth model systems to uncover the workings of the mammalian immune response to metazoan parasites, with the hope of revealing molecules and/or mechanisms that can be translated into better treatments for human autoimmune and idiopathic disorders. …”
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Numerical Analysis of a Dental Zirconium Restoration and the Stresses That Occur in Dental Tissues by Rosa Alicia Hernández-Vázquez, Guillermo Urriolagoitia-Sosa, Rodrigo Arturo Marquet-Rivera, Beatriz Romero-Ángeles, Octavio-Alejandro Mastache-Miranda, G. Guillermo Urriolagoitia-Calderón

“…This has led to the selection of materials very visually similar to the enamel, but unfortunately, their mechanical properties are not similar. This often translates into disadvantages than advantages. In the present work, a comparison is made of the stresses that occur during dental occlusion (dental bit) in a healthy dental organ and those that are generated in a dental organ with a dental zirconium restoration. …”
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Roles of Oncogenic Long Non-coding RNAs in Cancer Development by Hyunhee Do, Wanyeon Kim

“…Long non-coding RNAs (lncRNAs) are classified as RNAs that are longer than 200 nucleotides and cannot be translated into protein. Several studies have demonstrated that lncRNAs are directly or indirectly involved in a variety of biological processes and in the regulation of gene expression. …”
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Voir les fantômes. Sentir la multiplicité temporelle de la ville grâce aux œuvres d’art by Estelle Grandbois-Bernard

“…This article proposes to focus on how artists invest the time multiplicity of present to highlight and visually translate, and perhaps turn our attention to our living space. …”
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Usages et effets de la microsimulation dans l’élaboration d’une réforme. Un nouvel éclairage sur la création du RSA by Franck Bessis, Paul Cotton

“…Finally, a deductive use allows us to translate the political trade-offs and saturate the resulting constraints to obtain the precise parameters of the reform. …”
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The Flâneur’s Scopic Power or the Victorian Dream of Transparency by Estelle Murail

“…For the flâneur, being ‘transparent’ in the city is ultimately translating modernity through his gaze, footsteps, and words. …”
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Psychometric Properties of the Moore Index of Nutrition Self-Care in Arabic: A Study among Saudi Adolescents at King Saud University, Riyadh, Saudi Arabia by Adel Bashatah, Khalid A. Alahmary

“…The purpose of this study is to convert MIN-SC into the Arabic language and to test the translated tool for validity and reliability among adolescents in Saudi Arabia. …”
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Nuclear envelope components in vascular mechanotransduction: emerging roles in vascular health and disease by Tung D. Nguyen, Michael A. Winek, Mihir K. Rao, Shaiva P. Dhyani, Monica Y. Lee

“…The vascular network, uniquely sensitive to mechanical changes, translates biophysical forces into biochemical signals for vessel function. …”
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BPS states, conserved charges and centres of symmetric group algebras by Garreth Kemp, Sanjaye Ramgoolam

“…Using Schur-Weyl duality relations between unitary groups and symmetric groups, these questions translate into structural questions about the centres of symmetric group algebras. …”
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Time Series Prediction Based on Complex-Valued S-System Model by Bin Yang, Wenzheng Bao, Yuehui Chen

“…The time series data need to be translated into complex numbers. The hybrid evolutionary algorithm based on complex-valued restricted additive tree and firefly algorithm is proposed to search the optimal CVSS model. …”
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Hypoxia-Inducible Factor-1 as a Therapeutic Target in Endometrial Cancer Management by Laura M. S. Seeber, Ronald P. Zweemer, René H. M. Verheijen, Paul J. van Diest

“…Further work is needed to identify selective HIF-1 inhibitors and to translate these into clinical trials.…”
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Stochastic modelling of PTEN regulation in brain tumors: A model for glioblastoma multiforme by Margherita Carletti, Matteo Montani, Valentina Meschini, Marzia Bianchi, Lucia Radici

“…Moreover, the introduction of translational and transcriptional delays offers some interesting insights for the PTEN low expression as observed in brain tumor cells.…”
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Magnetic Resonance Imaging Evaluation of Closed-Mouth TMJ Disc-Condyle Relationship in a Population of Patients Seeking for Temporomandibular Disorders Advice by Matteo Tresoldi, Ricardo Dias, Alessandro Bracci, Marzia Segù, Luca Guarda-Nardini, Daniele Manfredini

“…Among DD, pure anteriorized position was the most common condition (34.4%), with different combined translational and rotational displacements in all the other joints (27.7%). …”
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A Multispecies Design Approach in the Eure valley. Three Lessons from a Design Studio in Landscape Architecture by Björn Bracke, Sophie Bonin, Bruno Notteboom, Hans Leinfelder

“…This article reflects on a design studio as an attempt to translate often complex and abstract conversations in more-than-human literature into concrete methods, plans and approaches for landscape architecture. …”
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Cooperative Fuzzy Games Approach to Setting Target Levels of ECs in Quality Function Deployment by Zhihui Yang, Yizeng Chen, Yunqiang Yin

“…Quality function deployment (QFD) can provide a means of translating customer requirements (CRs) into engineering characteristics (ECs) for each stage of product development and production. …”
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Mesenchymal Stem Cells as Therapeutics Agents: Quality and Environmental Regulatory Aspects by Patricia Galvez-Martin, Roger Sabata, Josep Verges, José L. Zugaza, Adolfina Ruiz, Beatriz Clares

“…Mesenchymal stem cells (MSCs) are one of the main stem cells that have been used for advanced therapies and regenerative medicine. To carry out the translational clinical application of MSCs, their manufacturing and administration in human must be controlled; therefore they should be considered as medicine: stem cell-based medicinal products (SCMPs). …”
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Ocho Pasos para Desarrollar un Plan Simple de Mercadeo by Edward A. Evans, Fredy H. Ballen

“…Ballen, and published by the UF Department of Food and Resource Economics. Translated into Spanish November 2015. (Photo credit: Thinkstock)  FE978/FE978: Ocho Pasos para Desarrollar un Plan Simple de Mercadeo (ufl.edu)   …”
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