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2321
RNA modifications: emerging players in the regulation of reproduction and development
Published 2024-11-01“…We discuss in detail how those modifications, along with their regulatory proteins, affect RNA processing, structure, localization, stability, and translation efficiency. We also highlight the associations among dysfunctions in RNA modification-related proteins, abnormal modification deposition and various diseases, emphasizing the roles of RNA modifications in critical developmental processes such as stem cell self-renewal and cell fate transition. …”
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2322
Design and Validation of the Flipped‐Learning Assessment Scale for Undergraduate Nursing Education
Published 2024-12-01“…Methods A cross‐sectional study was carried out in three phases ((1) item selection, rephrasing and translation; (2) content analysis through expert panel and (3) confirmatory factor analysis). …”
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2323
Operationalising routinely collected patient data in research to further the pursuit of social justice and health equity: a team-based scoping review
Published 2025-01-01“…Some (33.25%) directly referenced the use of their studies to examine translation of research to practice. Few studies (14.2%) specifically tackled issues pertaining to social justice, though many collected variables that could have been utilised for this purpose. …”
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2324
Bi-Josephson effect in a driven-dissipative supersolid
Published 2025-01-01“…We show that the spontaneous breaking of spatial translation symmetry in supersolid makes the location of the splitting barrier have a significant influence on the Josephson effect. …”
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2325
Cost-reduction strategy to culture patient derived bladder tumor organoids
Published 2025-02-01“…Abstract Organoids as self-organized structure derived from stem cells can recapitulate the function of an organ in miniature form which have developed great potential for clinical translation, drug screening and personalized medicine. …”
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2326
Morphologically-analyzed and syntactically-annotated Quran datasetMendeley Data
Published 2025-02-01“…This dataset is particularly valuable for tasks such as dependency parsing, grammar checking, machine translation, and text summarization. The potential applications of MASAQ are vast, ranging from pedagogical uses in teaching Arabic grammar to developing sophisticated NLP tools. …”
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2327
Activating CD137 Signaling Promotes Sprouting Angiogenesis via Increased VEGFA Secretion and the VEGFR2/Akt/eNOS Pathway
Published 2020-01-01“…We found activation of CD137 signaling for increased VEGFR2 transcription and translation steadily. Moreover, CD137 signaling activated phosphorylated VEGFR2 (Tyr1175) and the downstream Akt/eNOS pathway, whereas neutralizing CD137 signaling weakened the activation of VEGFR2 and the downstream Akt/eNOS pathway. …”
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2328
Canine Actors and Melodramatic Effects: The Dog of Montargis Arrives on the English Stage
Published 2017-11-01“…English adaptations soon followed, as translations from a variety of sources were presented before a public mesmerized by the feats of Dragon, the memorable canine character. …”
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2329
The Americanization of Arnold Schoenberg?. Theory, Analysis, and Reception
Published 2018-12-01“…After a preliminary overview of the availability of Schoenberg’s theoretical writing in English translation, four topics in Schoenberg’s thought are traced, with a focus on the post-war era: 1) harmony; 2) form; 3) thematic and motivic transformation; and 4) aesthetics. …”
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2330
Meta-Analysis of Expression Profiling Data Indicates Need for Combinatorial Biomarkers in Pediatric Ulcerative Colitis
Published 2020-01-01“…Unbiased studies using different genome-wide methods have identified a great number of candidate biomarkers for diagnosis and treatment response in pediatric ulcerative colitis (UC). However, clinical translation has been proven difficult. Here, we hypothesized that one reason could be differences between inflammatory responses in an inflamed gut and in peripheral blood cells. …”
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2331
Cell-Specific Regulation of Inflammatory Cytokines and Acute-Phase Proteins by the Glucocorticoid Receptor
Published 2023-01-01“…In PHH from donor 1, GR strongly inhibited LPS-induced CXCL1 and CXCL8 translation and transcription, whereas CXCL2 transcription tended to increase with DEX treatment. …”
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2332
New Resinogalea species from Araucaria araucana resin in Chile and reclassification of the genus in the Cryptocaliciomycetidae
Published 2023-08-01“…Further analyses applying the Genealogical Concordance Phylogenetic Species Recognition (GCPSR) based on ITS, mini chromosome maintenance protein complex (MCM7), RNA polymerase II second largest subunit (RPB2) and translation elongation factor 1-alpha (TEF) gene regions, confirmed that strains represent two new species. …”
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2333
Frameshift variation in the HMG-CoA reductase gene and unresponsiveness to cholesterol-lowering drugs in type 2 diabetes mellitus patients
Published 2025-01-01“…This mutation altered the amino acid sequence in the flap domain, replacing isoleucine with a stop codon. As a result, translation was prematurely terminated, leading to the production of truncated proteins.…”
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2334
Harnessing nanotechnology for cancer treatment
Published 2025-01-01“…Nevertheless, despite these progressions, obstacles still persist, particularly in the clinical translation of these technologies. Issues such as nanoparticle toxicity, biocompatibility, and the complexity of regulatory approval hinder the widespread adoption of nanomedicine in oncology. …”
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2335
A practical approach to building a calcareous nannofossil knowledge graph
Published 2025-01-01“…The knowledge graph, as a key technology for semantic translation and data fusion, offers a possible solution to these challenges. …”
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2336
PEBP1 amplifies mitochondrial dysfunction-induced integrated stress response
Published 2025-01-01“…Depletion of PEBP1 impaired mitochondrial ISR activation by reducing eukaryotic translation initiation factor 2α (eIF2α) phosphorylation and subsequent ISR gene expression, which was independent of PEBP1’s role in inhibiting the RAF/MEK/ERK pathway. …”
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2337
Purification of mesenchymal stromal cell‐derived small extracellular vesicles using ultrafiltration
Published 2025-01-01“…Abstract Mesenchymal stromal cell‐derived small extracellular vesicles (MSC‐sEVs) are pivotal for the curative effects of mesenchymal stromal cells, but their translation into clinical products is hindered by the technical challenges of scaled production and purification. …”
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2338
Psychometric Validation of the German Version of the Rapid Assessment of Physical Activity (RAPA): A Secondary Analysis of Cross‐Sectional Survey Data
Published 2025-01-01“…Methods We conducted a psychometric validation of a new German translation of the RAPA by performing a secondary analysis of survey data from 234 former cardiac rehabilitation patients (mean [SD] age 69 ± 11 years, 23% female) in Austria. …”
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2339
Effects of falls prevention interventions on falls outcomes for hospitalised adults: protocol for a systematic review with meta-analysis
Published 2017-11-01“…Updates will guide healthcare translation into practice.Trail registration number PROSPERO 2017: CRD 42017058887. …”
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2340
Do We Need A Bone Block Procedure in Recurrent Anterior Shoulder Instability?: A Case Report
Published 2023-04-01“…No block procedure effectively prevented future recurrence from the bone stop effect, which increases the glenoid cavity, stretching effect, and tensioning effect that prevents excessive humeral translation. Conclusion: In the case of RASI, treatment decisions need to be based on the patient's exact condition. …”
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