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4781
Neuroprotection against Amyloid-β-Induced DNA Double-Strand Breaks Is Mediated by Multiple Retinoic Acid-Dependent Pathways
Published 2020-01-01“…Whereas Aβ1-42 needs transcription and translation for DSB production, RA protects against Aβ1-42-induced DSBs at the posttranslational level through both the RARα/β/γ and PPARβ/δ receptors as demonstrated by using specific antagonists. …”
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4782
Adulthood trajectories of resilience and vulnerability: exploring gender differences in disadvantage after experience of out-of-home care
Published 2025-02-01“…Future research could examine gender differences in mechanisms translating into resilient or vulnerable trajectories, including the protective potential of education in relation to specific disadvantage patterns.…”
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4783
Prácticas Culturales para el Caqui Japonés en Florida
Published 2021-01-01“…Existen algunos otros condados dispersos que tienen más de 5 acres de caquis cultivados: Brevard (16 acres), Hernando (8 acres), y Jefferson (8 acres). Spanish Translation of HS1389 https://edis.ifas.ufl.edu/hs1401 …”
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4784
Advancements in Managing Anthracycline-Induced Cardiotoxicity: Insights from Interventional Clinical Trials
Published 2025-01-01“…Mei Zhao,1 Xiaohong Zhang,1 Dongyang Zhou,2 Junxian Song3– 5 1Department of Pharmacy, Peking University People’s Hospital, Beijing, People’s Republic of China; 2Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK; 3Department of Cardiology, Peking University People’s Hospital, Beijing, People’s Republic of China; 4Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Peking University People’s Hospital, Beijing, People’s Republic of China; 5Center for Cardiovascular Translational Research, Peking University People’s Hospital, Beijing, People’s Republic of ChinaCorrespondence: Junxian Song, Department of Cardiology, Peking University People’s Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, 100044, People’s Republic of China, Email sjx221@163.comPurpose: Anthracycline-induced cardiotoxicity (AIC) is a significant complication in cancer treatment, impacting long-term health outcomes. …”
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Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 provides insights into the pathogenesis of pseudoexfoliation glaucoma.
Published 2025-01-01“…MicroRNAs (miRNAs) are small non-coding RNA species that are involved in regulation of mRNA expression and translation. To investigate what glaucomatous changes occur in the trabecular meshwork and how these changes may be regulated by miRNAs, we performed a bioinformatics analysis resulting in a miRNA-mRNA interactome. …”
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4787
Subwavelength-scale off-axis optical nanomanipulation within Gaussian-beam traps
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Epigenetic Biomarkers and the Wnt/β-Catenin Pathway in Opisthorchis viverrini-associated Cholangiocarcinoma: A Scoping Review on Therapeutic Opportunities.
Published 2024-09-01“…However, additional validation is crucial for translating these novel insights into clinically applicable strategies, enhancing personalised Ov-CCA management approaches.…”
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Optimizing Healthcare Expenditure for Spinal Cord Stimulation in Italy: The Value of Battery Longevity Improvement and a Direct-to-Implant Approach
Published 2024-05-01“…**Conclusions:** Extended SCS battery longevity can translate into tangible cost savings for payers. The DTI approach for SCS supports National Healthcare System cost efficiencies and offers the additional benefits of optimizing operating room time while having only one recovery period for the patient.…”
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The Role of Nonmetastatic Lymph Nodes in the Survival of Colorectal Cancer: A Systematic Review
Published 2023-12-01Get full text
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4793
Heterogeneous foraging swarms can be better
Published 2025-01-01“…The resulting Aligned Effective Index (AEI) reward has the property that each individual can estimate the impact of its decisions on the swarm: individual improvements translate to swarm improvements. We show that AEI provably generalizes previous work, adding a component that computes the effect of counterfactual robot absence. …”
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Protocol for investigating astrocytic mitochondria in neurons of adult mice using two-photon microscopy
Published 2025-03-01Get full text
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Multi-omics analysis reveals the sensitivity of immunotherapy for unresectable non-small cell lung cancer
Published 2025-02-01Get full text
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Modern classification and molecular-genetic aspects of osteogenesis imperfecta
Published 2020-04-01“…In the last decade, it has become known that autosomal recessive, autosomal dominant and X-linked mutations in a wide range of genes, encoding proteins that are involved in the synthesis of type I collagen, its processing, secretion and post-translational modification, as well as in proteins that regulate the differentiation and activity of bone-forming cells, cause imperfect osteogenesis. …”
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4800
In Vivo Magic Angle Magnetic Resonance Imaging for Cell Tracking in Equine Low-Field MRI
Published 2019-01-01Get full text
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