Design and application of a puncture needle support (一种穿刺针支架的设计与应用) by WEI An (魏安), SUN Xiumei (孙秀梅), DU Chunliu (杜春柳)

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STRUCTURAL CAPITAL MANAGEMENT AND PERFORMANCE OF PUBLIC UNIVERSITIES IN NIGERIA by Fatima Bisola MAHMOUD, Mubaraq Sanni, Ismaila Daudu ALIU

“…These influence the performance of universities globally and locally in terms of knowledge generated through transmitting and conducting relevant research that translate into impactful innovation and development of the society. …”
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Modeling Radionuclide Transfer from Pasture to Milk in Kisoro, South- Western Uganda by Habakwiha V, Oruru B, Tumps Ireeta W

“…Comparing with the safe values of annual effective dose equivalent in foodstuffs of 0.14 mSv y l-1 which translates to excess cancer risk of 0.42 10-3, these contributions to radiological effects only account for about 1.5% of the total safe value of excess lifetime cancer risk, therefore, radionuclide transfer from pasture to milk causes a minimal radiation hazard to the milk consumers in Kisoro District.…”
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Students’ Attitudes and Performance in Mathematics in Secondary Schools in Kakira Town Council in Jinja District. by Kasononta, Ronald

“…The study found out that most students had a positive attitude towards mathematics and that they perceived mathematics as doable, learnable, and important yet this did not translate to good grades. Also, teachers had some challenges in teaching mathematics which included negative attitudes towards mathematics by most of the students, particularly girls, this was a common challenge to all teachers who responded to the questions. …”
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Factors associated with delays in seeking tuberculosis treatment among patients at Muhima district hospital, Rwanda by Mercy Nwankwo, Chinenye, Yasmin Omar, Umubyeyi

“…Data collected by researcher and trained research assistant, using a close- ended questionnaire through a translation in local dialect. Results: About 49% (24) of the smear- positive TB patients experienced delayed in seeking treatment for more than 180 days (6 months). …”
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Factors influencing male involvement in family planning among married couples seeking maternity and pediatric services in Chuk by Mercy Nwankwo, Chinenye, Immaculate, Okoth

“…Study instrument validated by pilot testing and translating into local language and data collection lasted for a period of one month. …”
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Current applications and challenges in large language models for patient care: a systematic review by Felix Busch, Lena Hoffmann, Christopher Rueger, Elon HC van Dijk, Rawen Kader, Esteban Ortiz-Prado, Marcus R. Makowski, Luca Saba, Martin Hadamitzky, Jakob Nikolas Kather, Daniel Truhn, Renato Cuocolo, Lisa C. Adams, Keno K. Bressem

“…Results We show that most studies investigate Generative Pre-trained Transformers (GPT)-3.5 (53.2%, n = 66 of 124 different LLMs examined) and GPT-4 (26.6%, n = 33/124) in answering medical questions, followed by patient information generation, including medical text summarization or translation, and clinical documentation. Our analysis delineates two primary domains of LLM limitations: design and output. …”
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Improving 10-year cardiovascular risk prediction in patients with type 2 diabetes with metabolomics by Ruijie Xie, Teresa Seum, Sha Sha, Kira Trares, Bernd Holleczek, Hermann Brenner, Ben Schöttker

“…Given the latest cost reduction and standardization efforts, NMR metabolomics has the potential for translation into the clinical routine. Graphical abstract…”
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Hyperosmotic Stress Induces a Specific Pattern for Stress Granule Formation in Human-Induced Pluripotent Stem Cells by Salam Salloum-Asfar, Rudolf Engelke, Hanaa Mousa, Neha Goswami, I. Richard Thompson, Freshteh Palangi, Kamal Kamal, Muna N. Al-Noubi, Frank Schmidt, Sara A. Abdulla, Mohamed M. Emara

“…Stress granules (SGs) are assemblies of selective messenger RNAs (mRNAs), translation factors, and RNA-binding proteins in small untranslated messenger ribonucleoprotein (mRNP) complexes in the cytoplasm. …”
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Cartilage structure-inspired nanofiber-hydrogel composite with robust proliferation and stable chondral lineage-specific differentiation function to orchestrate cartilage regenerat... by Yaqiang Li, Xiaowei Xun, Liang Duan, Erji Gao, Jiaxin Li, Lei Lin, Xinping Li, Aijuan He, Haiyong Ao, Yong Xu, Huitang Xia

“…Overall, the biomaterial system developed in this study provides a promising strategy for engineering transplantable, high-quality cartilage substitutes, with translational potential for artificial trachea construction.…”
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An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene by Fayeza Sadia Laskar, Md. Nazmul Islam Bappy, Md. Sowrov Hossain, Zenifer Alam, Dilruba Afrin, Sudeb Saha, Kazi Md. Ali Zinnah

“…Moreover, these nsSNPs exhibited substantial effects on structure, binding affinity with ligand, phylogenetic conservation, secondary structure, and post-translational modification sites of MET, which were evaluated using MutPred2, RaptorX, ConSurf, PSIPRED, and MusiteDeep, respectively. …”
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Evaluation of the cardiotoxicity of Echinochrome A using human induced pluripotent stem cell-derived cardiac organoids by Su-Jin Lee, Eunji Kim, Yeeun Jeong, Jae Boum Youm, Hyoung Kyu Kim, Jin Han, Elena A. Vasileva, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Sung Joon Kim, Hyang-Ae Lee

“…This study fills a critical gap and highlights the translational relevance of hCOs for cardiotoxicity assessment, demonstrating EchA's cardiac safety and supporting its potential therapeutic and environmental applications.…”
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JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression by Michala Prause, Christopher Michael Mayer, Caroline Brorsson, Klaus Stensgaard Frederiksen, Nils Billestrup, Joachim Størling, Thomas Mandrup-Poulsen

“…INS-1 cells express JNK1α1, JNK1α2, JNK1β1, JNK1β2, JNK2α1, JNK2α2, JNK3α1, and JNK3α2 mRNA isoform transcripts translating into 46 and 54 kDa isoform JNK proteins. …”
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Landscape composition and orchard management effects on bat assemblages and bat foraging activity in apple crops by Marcos Miñarro, Daniel García

“…Little is known, however, on how bat assemblages respond to the gradients imposed by anthropogenic landscapes and farming practices and how these environmental effects translate into changes in bat foraging. In this study, we use cider apple crop in northern Spain as a model to address the filtering effects of landscape composition and orchard management on, simultaneously, quantitative and qualitative characteristics of bat local assemblages and their foraging activity. …”
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Understanding the implementation of interventions to improve the management of frailty in primary care: a rapid realist review by David Reeves, Thomas Blakeman, Harm Van Marwijk, Khulud Alharbi, Jung Yin Tsang

“…Key factors that facilitate or inhibit the translation of frailty interventions into practice related to the distribution of resources; patient engagement and professional skill sets to address identified need.Conclusion There remain challenges to achieving successful implementation of frailty interventions in primary care. …”
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Adipose-Derived Stem Cells in Bone Tissue Engineering: Useful Tools with New Applications by Gabriele Storti, Maria Giovanna Scioli, Bong-Sung Kim, Augusto Orlandi, Valerio Cervelli

“…All these advancements are ultimately intended for a faster translational and clinical application of BTE.…”
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In situ natural radioactivity and radiological hazard assessments of granite gneiss outcrops in parts of the Southwestern Basement Complex of Nigeria by Adedibu Sunny Akingboye, Omowumi Ademila

“…However, increase in estimated mean of AGDE and ELCR; 525.620 and 1.273 above the world permissible standards of 300 and respectively does not translate to significant radiological threats. Therefore, control measure by constant monitoring of the radioactivity levels of the area and rocks should be practiced.…”
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High hemolytic activity in Staphylococcus aureus t1081/ST45 due to increased hla protein production and potential RNAIII-independent regulation by Yu-Tzu Lin, Ngoc-Niem Bui, Yu-Syuan Cheng, Cheng-Wen Lin, Chun-Li Lee, Tai-Fen Lee, Po-Ren Hsueh

“…Moreover, the higher translation levels may be independent of the known regulator RNAIII, indicating a potential RNAIII-independent mechanism for Hla regulation.…”
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The responsiveness of surgical research to Māori in Aotearoa, New Zealand—a scoping reviewResearch in context by Jamie-Lee Rahiri, Noah Appleby, Makayla Kahi, Annaliese Wheeler, Jason Tuhoe, Shanthi Ameratunga, Rachelle Love, Wiremu MacFater, Matire Harwood

“…Funding: This study was supported by a Health Research Council of New Zealand Health Delivery Research Activation Grant (21/860) and Māori Health Knowledge Translation Grant (25/234). The funders had no role in the study design, conception, data collection, analysis, interpretation, or report writing. …”
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Proteomic insights into dual-species biofilm formation of E. coli and E. faecalis on urinary catheters by Kidon Sung, Miseon Park, Ohgew Kweon, Angel Paredes, Alena Savenka, Saeed A Khan

“…E. coli exhibited a more proactive response, emphasizing motility, transcription, and protein synthesis for biofilm establishment; whereas E. faecalis displayed a more reserved strategy, potentially downregulating metabolic activity, transcription, and translation in response to cohabitation with E. coli. …”
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