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    Ticam2 ablation facilitates monocyte exhaustion recovery after sepsis by Blake A. Caldwell, Susanti Ie, Amy Lucas, Liwu Li

    Published 2025-01-01
    “…To determine the impact of TICAM2 ablation on innate epigenetic memory in sepsis, we measured genome-wide DNA methylation in bone marrow monocytes and found that Ticam2 -/- cells exhibit a unique profile of altered methylation at CEBPE binding sites and regulatory features for key immune genes such as Dmkn and Btg1. Bearing human translational relevance, a case study of time course blood samples collected from a sepsis patient presenting with SIRS and a positive qSOFA revealed a similar effect in human monocytes, which steadily transition into an exhausted memory characterized by a CD38high; CX3CR1low; HLA-DRlow state within four days of hospital admittance. …”
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  4. 4464

    CAN CLEAR ALIGNERS THERAPY ACHIEVE MAXILLARY EXPANSION IN PATIENTS WITH TRANSVERSE MALOCCLUSIONS? A SYSTEMATIC REVIEW by Ibraheem Bamaga

    Published 2024-12-01
    “…The efficacy of expansion with clear aligners was more prominent in the canine and premolar area, with the expansion mainly achieved with tipping movements rather than bodily translation movement. The planning software overpredicted the dental movements compared to what was achieved. …”
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    THE SOCIAL THEORY OF MAX WEBER IN CONFLICT OF INTERPRETATIONS by Zenonas Norkus

    Published 1999-01-01
    “…The confrontation of the system functionalism and conflict sociology during the first post-war decades led to "translation wars" in USA and gave rise to two competing images of Weber - a theorist of social order painted by T. …”
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