Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles in ischemic stroke: A meta-analysis of preclinical studies by Xiaoming Zhang, Yibing Guo, Kun Fang, Xiangqian Huang, Duo Lan, Mengqi Wang, Lina Jia, Xunming Ji, Ran Meng, Da Zhou

“…These findings pave the way for further research and potential clinical translation.…”
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Towards the praxis of a sustainable knowledge‑based economy by Agnieszka Klimska

“…Implementation of the preferred directions of development, requires not so much efficient, but proper management, i.e. one which would translate itself onto the plane of decision-making and, subsequently, that of application. …”
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The Future of Law Firms (and Lawyers) in the Age of Artificial Intelligence by Anthony E. Davis

“…Part I briefly describes some of the ways AI is already in use in ordinary life - from facial recognition, through medical diagnosis to translation services. Part II describes how AI is transforming what it means to provide legal services in six primary areas: litigation review; expertise automation; legal research; contract analytics; contract and litigation document generation; and predictive analytics. …”
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The decline of walleye populations: an ecological tipping point? by Greg G. Sass

“…Walleye/ogaa (Sander vitreus (Mitchill)) (hereafter, walleye; ogaa = Ojibwe translation) populations have historically supported important multi-use, harvest-oriented fisheries. …”
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Exploring the role and mechanisms of MAGEA4 in tumorigenesis, regulation, and immunotherapy by Weijian Zhu, Qiang Yi, Zheng Chen, Jiaqi Wang, Kui Zhong, Xinting Ouyang, Kuan Yang, Bowei Jiang, Jianing Zhong, Jinghua Zhong

“…This article comprehensively reviews the structure and function of MAGEA4, as well as recent research progress in solid tumors, providing a theoretical foundation for the clinical translation of MAGEA4 and its application in immunotherapy.…”
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The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons by Catherine Schaefers, Simone Rothmiller, Horst Thiermann, Theo Rein, Annette Schmidt

“…However, these often apply viral vectors, feeder cells, or antibiotics to generate hiPSC and MNs, limiting their translational potential. In this study, a virus-, feeder-, and antibiotic-free method was used for reprogramming hiPSC, which were maintained in culture medium produced under clinical good manufacturing practice. …”
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Re-Calibrating Network by Refining Initial Features Through Generative Gradient Regularization by Naim Reza, Ho Yub Jung

“…Notably, this refinement in features translates to improved generalization and the proposed method also eliminates the necessity of total retraining of the target network. …”
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Ceramic Hollow Fibre Constructs for Continuous Perfusion and Cell Harvest from 3D Hematopoietic Organoids by Mark C. Allenby, Asma Tahlawi, José C. F. Morais, Kang Li, Nicki Panoskaltsis, Athanasios Mantalaris

“…Herein, we propose HFs to improve 3D cell culture nutrient and metabolite diffusion, increase culture volume and cell density, and continuously harvest products for translational cell therapy biomanufacturing protocols.…”
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Injectable Hierarchical Bioactive Hydrogels with Fibroblast Growth Factor 21/Edaravone/Caffeic Acid Asynchronous Delivery for Treating Parkinson's Disease by Junpeng Xu, Peng Dai, Chen Zhang, Na Dong, Caiyan Li, Chonghui Tang, Zhihao Jin, Shih‐Ho Lin, Luyang Ye, Tianmiao Sun, Yukai Jin, Fenzan Wu, Lihua Luo, Ping Wu, Shengcun Li, Xiaokun Li, Shan‐hui Hsu, Dawei Jiang, Zhouguang Wang

“…The combination of clinical drugs targeting different symptoms with smart hydrogels to achieve asynchronous releases is highly translational and challenging. Here, a hierarchical bioactive hydrogel (OACDP) is designed with asynchronous release based on PD pathology. …”
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Glutamine missense suppressor transfer RNAs inhibit polyglutamine aggregation by Rasangi Tennakoon, Teija M.I. Bily, Farah Hasan, Sunidhi Syal, Aaron Voigt, Tugce B. Balci, Kyle S. Hoffman, Patrick O’Donoghue

“…HD-causative polyQ alleles lead to protein aggregation, which is a prerequisite for disease. Translation fidelity modifies protein aggregation, and several studies suggest that mutating one or two glutamine (Gln) residues in polyQ reduces aggregation. …”
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Establishment and characterization of ovarian clear cell carcinoma patient-derived xenografts by Joseph J. Caumanns, Shang Li, Gert J. Meersma, Evelien W. Duiker, Ate G. J. van der Zee, G. Bea A. Wisman, Steven de Jong

“…In conclusion, the high phenotypic and molecular similarity allows the established PDXs to serve as potential preclinical models for future translational research of OCCC.…”
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LINGUISTIC ASPECTS OF UNDERSTATEMENT IN MODERN ENGLISH by V. G. Ivanova

“…The author does not use the Russian variants of the translation of Understatement in the article, as they do not fully convey all the aspects of denotative and connotative meaning of this concept. …”
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Brain metabolites in ISIAH and Wistar rats by O. B. Shevelev, A. A. Seryapina, A. L. Markel, M. P. Moshkin

“…Due to the development of nuclear magnetic resonance spectroscopy (NMRS), a decrease in neuron viability in different parts of the brain in humans with hypertension has been shown. Translation of NMRS tools to the clinic requires the accumulation of empirical data about neurometabolic changes in a strictly controlled experiment. …”
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Effect of Orexin-A on Cortisol Secretion in H295R Cells via p70S6K/4EBP1 Signaling Pathway by Xiaocen Chang, Yuyan Zhao, Lei Guo

“…The aim of our study is to investigate the effect of orexin-A on cortisol secretion via the protein 70 ribosomal protein S6 kinase-1 (p70S6K) and eukaryotic translation initiation factor 4E binding proteins (4EBP1) signaling pathway in adrenocortical cells. …”
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Vibration mechanism study based on coupled dynamic model for TBM main drive system by Wenjun Xu, Hanyang Wu, Junzhou Huo, Dongyun Wang

“…At the same time, it is found that the coupled vibration of radial overturning vibration and lateral translation vibration is easy to appear in the actual system vibration. …”
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Strategy for Foreign Students’ Professional and Language Competence Development by E. S. Ionkina, O. S. Kharlamov

“…Developing the strategy aimed at the achievement of the professional and language competences by foreign pre-graduates, the authors implement various learning methods, such as a personality-oriented method, grammar-translation method, communicative method of teaching and a project method. …”
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The First Step of Health Policy-Making for Lifestyle Modifications at Middle Age: Problem Identification in 40- to 60-Year-Old Population, Northern Iran by Simin Mouodi, Seyed Reza Hosseini, Reza Ghadimi, Ali Bijani, Robert Graham Cumming, Hassan Ashrafian Amiri, Fatemeh Bayani, Shima Sum

“…This analytic research has been conducted as a cross-sectional study on the middle-aged (40–60 years old) population of Amirkola, Northern Iran. The Persian translation of the Health-Promoting Lifestyle Profile II questionnaire and the International Physical Activity Questionnaire were used for data collection. …”
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Molecular Mechanisms Underlying Neuroinflammation Intervention with Medicinal Plants: A Critical and Narrative Review of the Current Literature by Sandra Maria Barbalho, Beatriz Leme Boaro, Jéssica da Silva Camarinha Oliveira, Jiří Patočka, Caroline Barbalho Lamas, Masaru Tanaka, Lucas Fornari Laurindo

“…While the anti-inflammatory potential of these plants is significant, the variability in dosages and phytochemical compositions limits clinical translation. Here, we highlight that medicinal plants are effective modulators of neuroinflammation, underscoring their therapeutic potential. …”
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The Canadian Registry for Pulmonary Fibrosis: Design and Rationale of a National Pulmonary Fibrosis Registry by Christopher J. Ryerson, Benjamin Tan, Charlene D. Fell, Hélène Manganas, Shane Shapera, Shikha Mittoo, Mohsen Sadatsafavi, Teresa To, Andrea Gershon, Jolene H. Fisher, Kerri A. Johannson, Nathan Hambly, Nasreen Khalil, Theodore K. Marras, Julie Morisset, Pearce G. Wilcox, Andrew J. Halayko, Mohammad Adil Khan, Martin Kolb

“…As the largest and most comprehensive cohort of Canadian ILD patients, CARE-PF establishes a network for future clinical research and early phase clinical trials and provides a platform for translational and basic science research.…”
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Circulating MicroRNAs in Elderly Type 2 Diabetic Patients by Giuseppina Catanzaro, Zein Mersini Besharat, Martina Chiacchiarini, Luana Abballe, Claudia Sabato, Alessandra Vacca, Paola Borgiani, Francesco Dotta, Manfredi Tesauro, Agnese Po, Elisabetta Ferretti

“…Intra- and intergroup comparison of miRNA profiles pinpointed three miRNAs that correlated with responses to sitagliptin: miR-378, which is a candidate biomarker of resistance to this DPP-IVi, and miR-126-3p and miR-223, which are associated with positive responses to the drug. The translational implications are as immediate as evident, with the possibility to develop noninvasive diagnostic tools to predict drug response and development of chronic complications.…”
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