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4001
Inotersen to Treat Polyneuropathy Associated with Hereditary Transthyretin (hATTR) Amyloidosis
Published 2023-01-01“…By targeting TTR mRNA transcripts, Inotersen decreases protein translation and production, reducing the deposition of misfolded proteins. …”
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4002
Obraz edukacji wczesnoszkolnej w wypowiedziach nauczycieli edukacji przedmiotowej
Published 2020-03-01“…The early-school education model adopted by them translates to a large extent into the perception and evaluation of the resources of the 4th grade, which, in turn, sets the direction of the teaching communication activity in the school class, creating an environment for the student’s adaptation process at the beginning of learning in the 4th grade. …”
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4003
Monasterium, cella, abbatia… Enquête sur les différents termes désignant les communautés religieuses au haut Moyen Âge (ve-milieu ixe siècle) et leur signification
Published 2016-12-01“…For this reason, it is necessary to examine the historical and textual contexts of these terms carefully, before we translate or use them to characterize a religious community or its building.…”
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4004
Calibration between a panoramic LiDAR and a limited field-of-view depth camera
Published 2024-12-01“…Experimental results on simulation and real-world data demonstrate that the proposed methods in all three scenarios achieve precise calibration, maintaining average rotation and translation calibration errors within 2 degrees and 0.05 meters respectively for a $$360^{\circ }$$ 360 ∘ linear LiDAR and a depth camera with a field of view of $$100^{\circ }$$ 100 ∘ vertically and $$70^{\circ }$$ 70 ∘ degrees horizontally.…”
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4005
Potential Pitfalls of the Humanized Mice in Modeling Sepsis
Published 2018-01-01“…Although certain viral and protozoan infections can be replicated in humanized mice, whether a highly complex and dynamic systemic inflammation like sepsis can be accurately represented by current humanized mouse models in a clinically translatable manner is unclear. Humanized mice are xenotransplant animals in the most general terms. …”
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4006
Effect of Stocking Density on Stress-Related Gene Expression of Pacific White Shrimp (Litopenaeus vannamei) Infected with Infectious Myonecrosis Virus (IMNV)
Published 2024-10-01“…The upregulated genes were lectin and translationally controlled tumor protein (TCTP), while the downregulated gene was Toll Receptor. …”
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4007
Hypoxia-inducible factor in cancer: from pathway regulation to therapeutic opportunity
Published 2024-07-01“…This review will discuss the challenges and opportunities associated with translating HIF inhibition into clinical practice, including ongoing clinical trials and future directions in the development of HIF-based cancer treatments.…”
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4008
Deep Learning Approaches for 3D Model Generation from 2D Artworks to Aid Blind People with Tactile Exploration
Published 2024-12-01“…It is, therefore, presumable that the translation from 2D images to 3D models using such methods will be also in continuous development. …”
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4009
Structural engineering of stabilized, expanded epitope nanoparticle vaccines for HPV
Published 2025-01-01“…We further tested nanoparticles in a genetically diverse, more translationally relevant CD-1 mouse model and demonstrated that both E6 and E7 nanoparticle designs drove a CD8+ biased T-cell response. …”
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4010
A virtual slotframe technique for reliable multi-hop IEEE 802.15.4e time-slotted channel hopping network
Published 2018-07-01“…A slot scheduler will then perceive the virtual slotframe as merely a long slotframe. The devices can translate the schedules made for the longer slotframe into real links using the virtual slotframe technique. …”
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4011
Enhancing Environmental Control in Broiler Production: Retrieval-Augmented Generation for Improved Decision-Making with Large Language Models
Published 2025-01-01“…Among the promising advances in artificial intelligence (AI), large language models (LLMs) hold potential to enhance decision-making in broiler production by supporting environmental control through the interpretation of climatic data, the generation of reports to optimize conditions, guidance on ventilation adjustments, recommendations for thermal management, assistance in air quality monitoring, and the translation of simulation results into actionable suggestions to improve bird welfare. …”
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4012
Improving neuroendocrine tumor treatments with mathematical modeling: lessons from other endocrine cancers
Published 2025-02-01“…To illustrate this, we highlight examples of how mathematical modeling associated with more common endocrine cancers has been successfully used in the preclinical, translational and clinical settings. We also provide a scope of the limited work that has been done in NETs and map how these techniques can be utilized in NET research to address specific outstanding challenges in the field. …”
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4013
Global Transcriptomic Analysis of Inbred Lines Reveal Candidate Genes for Response to Maize Lethal Necrosis
Published 2025-01-01“…Additionally, the expression of translation initiation and elongation factors, <i>eIF4E</i> and <i>eIF4G</i>, correlated with the presence of MLN viruses. …”
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4014
Comparative Study on Leadership Styles and Customer Behavior: Environmentalist and Non-Environmentalist Students, Barcelona, Spain
Published 2025-01-01“…Despite this trend, there is a noticeable gap between attitudes and behaviors, with many environmentally conscious individuals needing help translating their values into consumer choices. The research uses a qualitative approach, combining semi-structured interviews and online questionnaires. …”
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4015
Image Processing Techniques for Assessing Contractility in Isolated Adult Cardiac Myocytes
Published 2009-01-01“…The proposed method not only provides a more comprehensive assessment of the myocyte contraction process but also can potentially eliminate historical concerns and sources of errors caused by myocyte rotation or translation during contraction. Furthermore, the versatility of the image processing techniques makes the method suitable for determining myocyte shortening in cells that usually bend or move during contraction. …”
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4016
Chronic Hyperglycemia Modulates Rat Osteoporotic Cortical Bone Microarchitecture into Less Fragile Structures
Published 2017-01-01“…Concluding, chronic hyperglycemia in ovariectomized female rats causes bone morphological changes that translate positively in the ultrastructure and mechanical properties of cortical bones.…”
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4017
Optogenetics Neuromodulation of the Nose
Published 2024-01-01“…Therefore, we focus on the progress in optogenetics and its application in neuromodulation of nociceptive stimuli and discuss the potential clinical translation for treating rhinitis in the future.…”
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4018
Camera Absolute Pose Estimation Using Hierarchical Attention in Multi-Scene
Published 2025-01-01“…Compared to the baseline algorithm PoseNet, our algorithm has achieved a 41.1% reduction in translation error and a 61.1% decrease in rotation error, demonstrating superior performance in multi-scene absolute camera pose regression.…”
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4019
Promoting cross-culture research on moral decision-making with standardized, culturally-equivalent dilemmas: The 4CONFiDe set
Published 2017-07-01“…Results: Both linear mixed models and Bayesian statistics confi rmed that moral choices were made irrespective of participants’ native language and dilemmas’ version, suggesting that the translation was culturally-representative. Moreover, they showed that the proposed dilemmas were perceived by participants with diff erent degrees of arousal, pleasantness and familiarity based on some of the conceptual factors and that three of the four conceptual factors (Personal force, Intentionality and Evitability) determined participants’ moral choices. …”
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4020
Development of Screening Tools for the Interpretation of Chemical Biomonitoring Data
Published 2012-01-01“…This paper describes a variety of approaches for development of screening-level exposure guidance values with translation from an external dose to a biomarker concentration framework for interpreting biomonitoring data in a risk context. …”
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