Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases by Ya-Min Ma, Lan Zhao

“…MicroRNAs (miRNAs) are the smallest class of noncoding RNAs, which widely exist in animals and plants. They can inhibit translation or overexpression by combining with mRNA and participate in posttranscriptional regulation of genes, resulting in reduced expression of target proteins, affecting the development, growth, aging, metabolism, and other physiological and pathological processes of animals and plants. …”
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A Dietary Treatment Improves Cerebral Blood Flow and Brain Connectivity in Aging apoE4 Mice by Maximilian Wiesmann, Valerio Zerbi, Diane Jansen, Roy Haast, Dieter Lütjohann, Laus M. Broersen, Arend Heerschap, Amanda J. Kiliaan

“…We further showed the efficacy of a multimodal translational approach, including advanced MR neuroimaging, to study dietary intervention on brain structure and function in aging.…”
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PaleoProPhyler: a reproducible pipeline for phylogenetic inference using ancient proteins by Patramanis, Ioannis, Ramos-Madrigal, Jazmín, Cappellini, Enrico, Racimo, Fernando

“…The pipeline can not only process various forms of proteomic data, but also easily harness genetic data in different formats (CRAM, BAM, VCF) and translate it, allowing the user to create reference panels for phyloproteomic analyses. …”
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Geospatial Relationships between Awareness and Utilization of Community Exercise Resources and Physical Activity Levels in Older Adults by Christopher J. Dondzila, Ann M. Swartz, Kevin G. Keenan, Amy E. Harley, Razia Azen, Scott J. Strath

“…It is unclear if community-based fitness resources (CBFR) translate to heightened activity levels within neighboring areas. …”
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Comparative analysis of models of sports development management on example of football industry: international experience and russian peculiarities by Sh. M. Ramazanov

“…The program intends to be an understandable mechanism of gaining reasonable income from translating football on the internet and TV and fair sharing of the income among the involved participants.…”
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The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells by Magdalena Maj, Gregor Hoermann, Sazan Rasul, Wolfgang Base, Ludwig Wagner, Johannes Attems

“…We observed that a MAPT overexpressing cell line demonstrates altered insulin transcription, translation, and insulin secretion rates. We found the relative insulin secretion rates were significantly decreased in a MAPT overexpressing cell line and these findings could be confirmed using partial MAPT knock-down cell lines. …”
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Deep learning in microbiome analysis: a comprehensive review of neural network models by Piotr Przymus, Krzysztof Rykaczewski, Adrián Martín-Segura, Jaak Truu, Enrique Carrillo De Santa Pau, Mikhail Kolev, Mikhail Kolev, Irina Naskinova, Aleksandra Gruca, Alexia Sampri, Alexia Sampri, Marcus Frohme, Alina Nechyporenko, Alina Nechyporenko

“…As microbiome research continues to generate vast and complex datasets, addressing these challenges will be crucial for advancing microbiological insights and translating them into practical applications with DL. …”
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STADIUM: Species-Specific tRNA Adaptive Index Compendium by Jonghwan Yoon, Yeun-Jun Chung, Minho Lee

“…The tAI is a measure of translational efficiency for a gene and is calculated based on the abundance of intracellular tRNA and the binding strength between a codon and a tRNA. …”
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Study on the Instability Mechanism and Grouting Reinforcement Repair of Large-Scale Underground Stopes by Chengyu Xie, Nan Jia, Liwen He

“…The damage mode of instability collapse is a combination method of wedge collapse, circular arc rotation, triangular translation, and strip slip. According to the multiphysics coupling numerical calculation, the diffusion radius of the grouting slurry is 12 m, exhibiting an elliptical distribution. …”
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Cardiac function and quality of life improvement with fasudil hydrochloride in patients with diabetes post-PCI: a randomized controlled trial by Xuejia Yang, Qian Li, Yaning Liu, Ran Chen, Yanjing Liu, Chenghui Sun, Licha Kong, Qiuli Dong

“…Conclusions Fasudil hydrochloride effectively targets endothelial dysfunction and atherosclerosis, contributing to better cardiac performance and metabolic regulation. These effects translate into improved post-PCI quality of life for patients with diabetes and CHD. …”
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Limits and Risks of Digital Transformation by T. S. Akhromeeva, G. G. Malinetskiy, S. A. Posashkov

“…It is very likely that the tester of artificial intelligence systems will become one of the mass professions in the close future.We give examples to show that the "translation" from "continuous" to "discrete" language can lead to qualitatively different behavior of mathematical models. …”
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Implementation of evidence-based parenting programs under real-world conditions: Protocol for a scoping review. by Rita Pinto, Catarina Canário, Orlanda Cruz, Maria José Rodrigo

“…This scoping review will help to bridge the implementation gap between research evidence and its translation into practice.…”
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A Relationship between Epithelial Maturation, Bronchopulmonary Dysplasia, and Chronic Obstructive Pulmonary Disease by Abraham B. Roos, Tove Berg, Magnus Nord

“…Increased knowledge of the mechanisms contributing to early onset COPD among BPD survivors could translate into improved treatment strategies and reduced frequency of respiratory disorders among adult survivors of BPD. …”
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Photobiomodulation: An Effective Approach to Enhance Proliferation and Differentiation of Adipose-Derived Stem Cells into Osteoblasts by Daniella Da Silva, Anine Crous, Heidi Abrahamse

“…Likewise, the optimal laser parameters that could improve the proliferation and differentiation of ADSC, translating into clinical success, will be commented on.…”
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Peptide-Based Vaccination Therapy for Rheumatic Diseases by Bin Wang, Shiju Chen, Qing Zheng, Yuan Liu, Guixiu Shi

“…However, most studies available now have been mainly based on animal models, while evidence from clinical studies is still lacking. The translation of these advances from experimental studies into clinical therapy remains impeded by some obstacles such as species difference in immunity, disease heterogeneity, and lack of safe delivery carriers or adjuvants. …”
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The Role of Adipose-Derived Stem Cells in Breast Cancer Progression and Metastasis by Riccardo Schweizer, Wakako Tsuji, Vijay S. Gorantla, Kacey G. Marra, J. Peter Rubin, Jan A. Plock

“…Herein, we aimed to concisely review current experimental findings on the interaction of mesenchymal stem cells and breast cancer, mainly focusing on ADSCs as a promising tool for regenerative medicine, and discuss the implications in clinical translation.…”
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A Magnetohydrodynamics Simulation of Coronal Mass Ejections in the Upper Corona at 2.5R⊙ ≤ r ≤ 19R⊙ by Keiji Hayashi, Chin-Chun Wu, Kan Liou

“…To determine the numerical perturbation on the 2.5 R _⊙ inner boundary surface, a kinetic self-similar model with a torus-shaped magnetic-field rope and a spherically symmetric plasma structure translating and expanding at the constant speed (named TICK model) is developed. …”
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Knowledge, distributed leadership and (structured) agency: a view on academic policy curation by Françoise McKay

“…The discussion will underscore their importance as not simply translators but narrators of academic policy. The piece will close with some reflections on the personal, cultural and structural constraints that limit the value that these professionals can bring to their universities. …”
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Numerical Analysis on the Effects of Binary Interaction between Typhoons Tembin and Bolaven in 2012 by Zhipeng Xian, Keyi Chen

“…The results show that the presence of monsoon made the binary interaction more complex by affecting the tracks and the translation speeds of the TCs. The influence of Bolaven on the track of Tembin was more significant than the influence of Tembin on the track of Bolaven, and the looping track of Tembin was also affected by the external surrounding circulation associated with Bolaven. …”
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On the Imperative of Language for Understanding African Art by Rowland Abiodun

“…For the benefit of those not literate in Yorùba language, Michael Af ́ ọlayan gave an elegant translation of Okediji’s paper in English. The excellent contents and presentation by Okediji touched on issues that lay at the heart of my book, namely its methodology and its insistence on the need for a Yorùbá voice to be heard literally and metaphorically in art historical discourse. …”
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