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3861
The NLRP3 Inflammasome as a Novel Player of the Intercellular Crosstalk in Metabolic Disorders
Published 2013-01-01“…Both clinical and translational laboratory studies have demonstrated that chronic inflammation is associated with obesity and obesity-related conditions such as insulin resistance. …”
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3862
Evaluation Formulas for Generalized Conditional Wiener Integrals with Drift on a Function Space
Published 2013-01-01“…In this paper we derive a translation theorem for a generalized Wiener integral and then prove that Y is a generalized Brownian motion process with drift a. …”
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3863
Aleksandr Bogdanov’s Sociology of the Arts
Published 2021-12-01“…It will enable culturologists and other scholars to include Bogdanov in the history of the sociology of the arts, an exercise that has hitherto been impeded by Soviet censorship of his works, under-tuition of the Russian language, and a scarcity of relevant translations.…”
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3864
Development of a cell-penetrating peptide-based nanocomplex for long-term delivery of intact mitochondrial DNA into epithelial cells
Published 2025-03-01“…Gene therapy approaches for mitochondrial DNA (mtDNA)-associated damage/diseases have thus far been limited, and despite advancements in single gene therapy for mtDNA mutations and progress in mitochondrial transplantation, no method exists for restoring the entire mtDNA molecule in a clinically translatable manner. Here, we present for the first time a strategy to deliver an exogenous, fully intact, and healthy mtDNA template into cells to correct endogenous mtDNA mutations and deletions, with the potential to be developed into an efficient pan-therapy for inherited and/or acquired mtDNA disorders. …”
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3865
The Roman catastrophe of 1527 in the Italian Wars, or Sacco di Roma: analysis of the historical interpretation of the event by several contemporaries
Published 2024-12-01“…As an appendix to the study, there is a translation from Italian into Russian of Vettori’s dialog fragment by the same name “Sacco di Roma”, in which the diplomat expresses his ideas about the papacy through the mask of a fictional character – the Florentine Antonio.…”
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3866
Nitric Oxide in Cerebral Vasospasm: Theories, Measurement, and Treatment
Published 2013-01-01“…Both theories have strong experimental evidence behind them and hold promise for translation into clinical practice. Furthermore, NO donors show definitive promise for preventing vasospasm at the angiographic and clinical level. …”
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3867
Constraint of Different Knee Implant Designs Under Anterior–Posterior Shear Forces and Internal–External Rotation Moments in Human Cadaveric Knees
Published 2025-01-01“…In contrast, the medial-stabilized implant exhibited less anterior–posterior translation medially than laterally, without constraining the medial condyle to a fixed position. …”
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3868
Um panorama da literatura sobre a internacionalização das religiões ayahuasqueiras brasileiras
Published 2017-01-01“…The process of internationalization of these groups involves complex nets and transnational alliances, generating intriguing issues on cultural translation and religious diaspora. Nevertheless, the theme is rarely explored and the information is widely scattered. …”
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3869
Novel Visualization of Building Earthquake Response Recorded by a Dense Network of Sensors
Published 2025-01-01“…The animations provide invaluable insight into the 3D structural response of the building as a whole, including wave propagation through the structure and the interplay between translations and rotations, which will be useful for testing existing and developing new methods for structural health monitoring of buildings and for the further development of building design codes. …”
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3870
Evolutionary analysis of the DHHCs in Saccharinae
Published 2025-01-01“…Abstract The DHHC domain genes are crucial for protein lipid modification, a key post-translational modification influencing membrane targeting, subcellular trafficking, and protein function. …”
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3871
Modulation of Dental Pulp Stem Cell Odontogenesis in a Tunable PEG-Fibrinogen Hydrogel System
Published 2015-01-01“…Injectable hydrogels have the great potential for clinical translation of dental pulp regeneration. A recently developed PEG-fibrinogen (PF) hydrogel, which comprises a bioactive fibrinogen backbone conjugated to polyethylene glycol (PEG) side chains, can be cross-linked after injection by photopolymerization. …”
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3872
Key Role of Phosphorylation in Small Heat Shock Protein Regulation via Oligomeric Disaggregation and Functional Activation
Published 2025-01-01“…Phosphorylation, a key post-translational modification (PTM), plays a dynamic role in regulating sHSP structure, oligomeric state, stability, and chaperone function. …”
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3873
When Analysts turn into Boxers: An Introduction to Pre-Sales Requirements Engineering
Published 2015-07-01“…The latter are needed to translate the customers’ needs to features, to efforts, and eventually to costs. …”
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3874
Investigating the Possibility to Reduce the Residual Stress Level in 2.5D Cutting Using Titanium Coated Carbide Ball End Mill
Published 2014-01-01“…It is widely used in cutting 2.5D profiles such as point-to-point, contouring, and pocketing operations. 2.5D machining possesses the capability to translate in all 3 axes but can perform the cutting operation in only 2 of the 3 axes at a time. …”
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3875
The nonlinear cysteine redox dynamics in the i-space: A proteoform-centric theory of redox regulation
Published 2025-04-01“…The post-translational redox regulation of protein function by cysteine oxidation controls diverse biological processes, from cell division to death. …”
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3876
Vietnamese Sentiment Analysis under Limited Training Data Based on Deep Neural Networks
Published 2022-01-01“…This paper uses the preprocessing techniques to clean and normalize the data and generate the new samples from the limited training dataset based on many text augmentation techniques such as lexicon substitution, sentence shuffling, back translation, syntax-tree transformation, and embedding mixup. …”
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3877
Neo-BCV: A Novel Bacterial Liquid Complex Vaccine for Enhancing Dendritic Cell-Mediated Immune Responses Against Lung Cancer
Published 2025-01-01“…Conclusions: These findings highlight Neo-BCV’s potential as a safe and effective therapeutic strategy, offering a novel avenue for clinical translation in lung cancer immunotherapy.…”
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3878
Introducing the Canadian Thoracic Society Framework for Guideline Dissemination and Implementation, with Concurrent Evaluation
Published 2013-01-01“…The authors describe the new CTS Framework for Guideline Dissemination and Implementation, with Concurrent Evaluation, which has three spheres of action: guideline production, implementation infrastructure and knowledge translation (KT) methodological support. The Canadian Institutes of Health Research ‘Knowledge-to-Action’ process was adopted as the model of choice for conceptualizing KT interventions. …”
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3879
The impact of terahertz radiation on an extremophilic archaean Halorubrum saccharovorum proteome
Published 2017-02-01“…The obtained data suggest that Halorubrum cells respond to exposure to terahertz radiation by expression changes in gene products involved in translation regulation.…”
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3880
The Adaptive Neuroplasticity Hypothesis of Behavioral Maintenance
Published 2012-01-01“…In this paper we will: (1) describe the enormous potential for neuroplasticity in older adults; (2) review stress and depression as examples of maladaptive neuroplasticity; (3) describe an example of adaptive neuroplasticity achieved with a behavioral intervention that induced positive affect in people with CHD; and (4) discuss implications for future work in bench to bedside translational research.…”
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