Codon Usage is Influenced by Compositional Constraints in Genes Associated with Dementia by Taha Alqahtani, Rekha Khandia, Nidhi Puranik, Ali M. Alqahtani, Yahia Alghazwani, Saad Ali Alshehri, Kumarappan Chidambaram, Mohammad Amjad Kamal, Mohammad Amjad Kamal, Mohammad Amjad Kamal, Mohammad Amjad Kamal

“…Furthermore, parity analysis, higher translational selection value, preference of GC-ending codons over AT-ending codons, and association of gene length with gene expression refer to the dominant role of selection pressure with compositional constraint and mutational force-shaping codon usage.…”
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Cross-cultural validation and psychometric properties study of the Chinese college students’ life skills scale for sport—transfer scale by Lin Luo, Meilin He, Shaojing Wen, Junfeng Yuan, Huilin Xu

“…In the first phase, four translation experts and five academic researchers collaborated to develop the Chinese version of the scale (C-LSSS-TS). …”
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Noninvasive Optical Imaging and In Vivo Cell Tracking of Indocyanine Green Labeled Human Stem Cells Transplanted at Superficial or In-Depth Tissue of SCID Mice by Vikram Sabapathy, Jyothsna Mentam, Paul Mazhuvanchary Jacob, Sanjay Kumar

“…Recent studies have shown how real-time in vivo molecular imaging has helped in identifying hurdles towards clinical translation and designing potential strategies that may contribute to successful transplantation of stem cells and improved outcomes. …”
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Immunological Regulation of Fibrosis During Heart Failure: It Takes Two to Tango by Vinay Kumar, Shyam S. Bansal

“…The aims of this review are to (i) briefly summarize the role of key immune cells that regulate wound healing during MI and fibrosis during LV remodeling; (ii) underscore phenotypic diversities in immune cells and their subsets to underscore their role in regulating fibrotic responses, and, last but not the least, (iii) highlight gaps in our understanding that restrict the translation of immuno-modulatory therapies from the preclinical models to heart failure patients.…”
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Optimization of the intron sequences combined with the CMV promoter increases recombinant protein expression in CHO cells by Ting-Ting Xu, Yan-Fang Wang, Jing-Jia Yuan, Chun-Liu Mi, Shao-Lei Geng, Xiao-yin Wang, Tian-Yun Wang

“…Transcriptomics analysis was performed and found that differential expression of genes involved in mRNA processing, RNA export from nucleus, cytoplasmic translation, transcriptional activation and cell cycle regulation. …”
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2020 Cool-Season Forage Variety Recommendations for Florida by A. R. Blount, M. Wallau, E. Rios, J. M. B. Vendramini, J. C. B. Dubeux, Md. A. Babar, K. E. Kenworthy, M. J. Mulvaney, K. H. Quesenberry

“…These plants are usually higher in total digestible nutrients (TDN) and crude protein (CP) than summer perennial grasses, translating into greater animal performance (Dubeux et al., 2016). …”
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Landscape analysis of m6A modification reveals the dysfunction of bone metabolism in osteoporosis mice by Lifeng Zheng, Chao Lan, Xinyue Gao, An Zhu, Yaoqing Chen, Jinluan Lin, Sunjie Yan, Ximei Shen

“…The m6A modification, a prevalent form of chemical RNA modification, primarily regulates posttranscriptional processes, including RNA stability, splicing, and translation. Numerous studies have underscored the crucial functions of m6A regulators in OP. …”
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GLP-1 Receptor Agonists and Cardiovascular Disease in Patients with Type 2 Diabetes by María Isabel del Olmo-Garcia, Juan Francisco Merino-Torres

“…GLP-1 RA actions not only translate on an improvement of well-known cardiovascular risk factors such as glycaemic control, dyslipidaemia, weight, or arterial hypertension but also might show benefits on endothelial function, coronary ischaemia, and heart failure. …”
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Monte Carlo Simulations in Nanomedicine: Advancing Cancer Imaging and Therapy by James C. L. Chow

“…This topical review underscores the transformative potential of MC simulations in bridging fundamental research and clinical translation. By facilitating personalized nanomedicine and streamlining regulatory and clinical trial processes, MC simulations offer a pathway toward more effective, tailored, and accessible cancer treatments. …”
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Ethanol-Induced Alterations of T Cells and Cytokines after Surgery in a Murine Infection Model by Nadine Lanzke, Mario Menk, Clarissa von Haefen, Lilit Sargsyan, Bianca Scharf, Klaus-Dieter Wernecke, Claudia D. Spies

“…Expression of transcription factors of T helper cell lineage commitment did not translate into different counts of T helper cells. …”
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Wind Power Assessment Based on a WRF Wind Simulation with Developed Power Curve Modeling Methods by Zhenhai Guo, Xia Xiao

“…Although the probability distribution functions (pdfs) of the wind speed are commonly used, their seemingly good performance for distribution may not always translate into an accurate assessment of power generation. …”
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Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders by Mi Eun Kim, Jun Sik Lee

“…Despite significant progress, challenges remain in translating these findings into clinically viable therapies. …”
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Marine natural products as a source of novel anticancer drugs: an updated review (2019–2023) by Hesham R. El-Seedi, Mohamed S. Refaey, Nizar Elias, Mohamed F. El-Mallah, Faisal M. K. Albaqami, Ismail Dergaa, Ming Du, Mohamed F. Salem, Haroon Elrasheid Tahir, Maria Dagliaa, Nermeen Yosri, Hongcheng Zhang, Awg H. El-Seedi, Zhiming Guo, Shaden A. M. Khalifa

“…Furthermore, it addresses the challenges and opportunities associated with the development of marine-derived anticancer drugs, including issues related to supply, sustainability, synthesis, and clinical translation. Finally, the review underscores the immense potential of marine natural products as a valuable reservoir of novel anticancer agents and advocates for continued exploration and exploitation of the marine environment to address the unmet medical needs in cancer therapy Graphical Abstract…”
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Nonviral Gene Delivery of Growth and Differentiation Factor 5 to Human Mesenchymal Stem Cells Injected into a 3D Bovine Intervertebral Disc Organ Culture System by Christian Bucher, Amiq Gazdhar, Lorin M. Benneker, Thomas Geiser, Benjamin Gantenbein-Ritter

“…In this study we demonstrate the potential of GDF5 transfected MSC as a promising approach for clinical translation for disc regeneration.…”
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miRNAs and Melanoma: How Are They Connected? by Adriana Taveira da Cruz, Miriam Galvonas Jasiulionis

“…miRNAs are non-coding RNAs that bind to mRNA targets and disturb their stability and/or translation, thus acting in gene posttranscriptional regulation. …”
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The Integration of Nanotechnology and Biology for Cell Engineering: Promises and Challenges by Uma Maheswari Krishnan, Swaminathan Sethuraman

“…Importance: Though the use of nanomaterials has improved tissue engineering, many pitfalls still exist that present a roadblock in the translation of tissue engineering strategies to clinical practice. …”
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State-of-the-Art Techniques to Causally Link Neural Plasticity to Functional Recovery in Experimental Stroke Research by Anna-Sophia Wahl

“…Research of recent years has shown the tremendous potential of the central nervous system to react to noxious stimuli such as a stroke: Increased plastic changes leading to reorganization in form of neuronal rewiring, neurogenesis, and synaptogenesis, accompanied by transcriptional and translational turnover in the affected cells, have been described both clinically and in experimental stroke research. …”
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Application of Physiologically Based Pharmacokinetic Models in Chemical Risk Assessment by Moiz Mumtaz, Jeffrey Fisher, Benjamin Blount, Patricia Ruiz

“…During the past two decades, through cooperative agreements and contracts at several research and higher education institutions, ATSDR funded translational research has encouraged the use of various types of models. …”
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Role of HNF6 in liver homeostasis and pathophysiology by Miaomiao Tian, Weizhen Gao, Shujun Ma, Huiling Cao, Yu Zhang, Fuxiang An, Jianni Qi, Zhen Yang

“…Its expression is affected by epigenetic modifications such as DNA methylation, post-translational modifications, and microRNAs. Recently, HNF6 was also found to be expressed in tissues, such as the pancreas, intestine, and lungs, where it controls their formation by regulating cell differentiation and influences their pathophysiological processes via various mechanisms. …”
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Current trends in peanut allergy immunotherapy: a review by Klementyna Łyżwa, Anna Krupa-Łaska, Joanna Zielińska, Marek Kulus, Katarzyna Grzela

“…Combining immunotherapy with adjuvants such as omalizumab and dupilumab or probiotics is promising, but it raises questions about sustained efficacy and patient response after treatment discontinuation. In addition, the translation of clinical trial results into real-world settings remains a critical issue, as shown by low participation rates in immunotherapy programs. …”
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