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3741
Assessing spacer acquisition rates in E. coli type I-E CRISPR arrays
Published 2025-01-01“…In addition, the expression of heterologous non-homologous end-joining DNA-repair genes was found to augment spacer acquisition rates, translating to enhanced phage infection defense. Together, these results demonstrate the impact of intracellular factors that modulate spacer acquisition and identify an intrinsic fitness effect associated with array-expanded populations.…”
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3742
Human immune system: Exploring diversity across individuals and populations
Published 2025-01-01“…This review systematically organizes these findings, with the goal of emphasizing the potential of targeted interventions to address health disparities and advance translational research, enabling a more comprehensive strategy. …”
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3743
Regulation of viral replication by host restriction factors
Published 2025-01-01“…These cellular proteins inhibit viral replication and spread by impeding essential steps in the viral life cycle, such as viral entry, genome transcription and replication, protein translation, viral particle assembly, and release. This review summarizes the current understanding of how host restriction factors inhibit viral replication, with a primary focus on their diverse antiviral mechanisms against a range of viruses, including SARS-CoV-2, influenza A virus, enteroviruses, human immunodeficiency virus, hepatitis B virus, and human papillomavirus. …”
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3744
Information security of minors: individual subjects of the Russian Federation organization experience
Published 2023-02-01“…At the end of the study, conclusions about the translation of positive experience were made.…”
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3745
Topology controls flow patterns in active double emulsions
Published 2025-02-01“…First, a double emulsion with a single active droplet becomes self-motile, and there is a transition between translational and rotational motion: both of these regimes remain defect-free, hence topologically trivial. …”
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3746
Polariser l'écart : la mise en scène du décalage dans Fram de Tony Harrison
Published 2011-10-01“…Best known as a poet, Tony Harrison is also a translator and playwright; his 2008 play Fram was badly received by critics, perhaps because it plays on key structural discrepancy, embedding as it does the story of Nansen, the polar explorer (with the eponymous boat he designed, Fram) within the frame of a play written by the ghost of the late academic Gilbert Murray. …”
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3747
Pre-Service Teachers’ Cognitive and Metacognitive Processes in Integrated STEM Modeling Activity
Published 2021-02-01“…Additionally, Lesh Translation Model was used to decide the representations of mathematical content knowledge codes for metacognitive activities. …”
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3748
Validity and Reliability of the Malay Version of the Planned Happenstance Career Inventory for Malaysian University Students
Published 2024-06-01“… This study aimed to translate and validate the Planned Happenstance Career Inventory (PHCI) for use in a Malaysian context. …”
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3749
Exploring the Revolutionary Impact of YAP Pathways on Physical and Rehabilitation Medicine
Published 2025-01-01“…YAP is known for its capacity to perceive and translate mechanical signals into specific transcriptional programs within cells. …”
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3750
Updating the Content of Higher Education in the Context of Modern Sociocultural Trends
Published 2021-07-01“…As a result of the update of the hidden education content by the sociocultural aspect, it is transformed into an implicit (updated hidden), which, while not being declared, but being adapted and purposeful in reflecting and translating sociocultural experience, improves the training of specialists in various directions and profiles, implements the leading principle of higher education.…”
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3751
Theoretical and Numerical Studies of Dynamic Scaling of a Six-Degree-of-Freedom Laser Propulsion Vehicle
Published 2015-01-01“…The dynamic scaling law for a single pulse was constructed using translational and angular equations of motion. The analytical scaling was confirmed for a single-pulse incident using a fluid-orbit coupling simulator for the interaction between the blast wave and the vehicle. …”
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3752
miRNAomic Approach to Plant Nitrogen Starvation
Published 2021-01-01“…One of the important and recently discovered groups of regulatory molecules acting at the posttranscriptional and translational levels are microRNAs (miRNAs). miRNAs are known to play critical roles in the regulation of gene expression in plants under different stress conditions including N stress. …”
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3753
Trends in Summer Season Climate for Eastern Europe and Southern Russia in the Early 21st Century
Published 2016-01-01“…Finally, the results of this study can be used to translate larger-scale seasonal or climate forecasts to the regional scale.…”
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3754
Airway basal stem cell therapy for lung diseases: an emerging regenerative medicine strategy
Published 2025-01-01“…Additionally, the review also discusses the technical and biological challenges in translating these research findings into clinical applications and offers prospective views on future research directions, therefore broadening the landscape of pulmonary regenerative medicine.…”
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3755
The Network Global Optimal Mapping Approach Utilizing a Discrete Firefly Optimization Algorithm
Published 2022-01-01“…The local map is converted using a set having a respective free rotation. Then, the translation is reflected by a global map of each local map using the affine transformation. …”
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3756
You Take Care of the Drive, I Take Care of the Rule: A Traffic-Rule Awareness System Using Vehicular Sensors and Mobile Phones
Published 2012-12-01“…In this paper, we propose a novel traffic-rule awareness system using vehicular sensors and mobile phones. It translates traffic rules into combinations of vehicular sensors, GPS device, and Geography Information System (GIS); the system can tell whether a driver violates the traffic rules and help him to amend his driving behaviour immediately. …”
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3757
Innate and Adaptive Immunity in Calcific Aortic Valve Disease
Published 2015-01-01“…Herein, we are reviewing the link between the immune response and the development of CAVD and we have tried, whenever possible, to keep a translational approach.…”
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3758
Emerging Strategies for Revascularization: Use of Cell-Derived Extracellular Vesicles and Artificial Nanovesicles in Critical Limb Ischemia
Published 2025-01-01“…The review spans the spectrum from early preclinical investigations to the latest translational advancements, providing a comprehensive overview of the current state of research in this emerging field. …”
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3759
Epidemiology of Diabetic Foot Ulcers and Amputations in Romania: Results of a Cross-Sectional Quality of Life Questionnaire Based Survey
Published 2016-01-01“…Compared to patients without foot ulcers, those with foot ulcers had significantly higher scores for total DN and all its subdomains translating to worse QOL (p<0.001). This analysis showed a high rate of foot ulcers and amputations in Romanian diabetic patients. …”
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3760
Tuning of a Viscous Inerter Damper: How to Achieve Resonant Damping Without a Damper Resonance
Published 2025-01-01“…The resonant damper performance by the non-resonant viscous inerter damper is illustrated by a numerical example with a 20-story building model, for which the desired resonant modal interaction requires an inertance of almost ten times the entire translational building mass.…”
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