Studies on Prion Replication in Spleen by Alex J. Raeber, Fabio Montrasio, Ivan Hegyi, Rico Frigg, Michael A. Klein, Adriano Aguzzi, Charles Weissmann

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Ultrasound Backscatter Microscopy Image-Guided Intraventricular Gene Delivery at Murine Embryonic Age 9.5 and 10.5 Produces Distinct Transgene Expression Patterns at the Adult Stage by Jiwon Jang, Jyhyun Ahn, Nayeon Lee, Seong-Tae Kim, Dae-Hyuk Kweon, Jae Youl Cho, Kye Won Park, Sunyoung Kim, Keejung Yoon

“…Therefore, by injecting a transgene before or after E10, transgene expression can be manipulated to be local or systemic. …”
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Effects of Human Alpha-Synuclein A53T-A30P Mutations on SVZ and Local Olfactory Bulb Cell Proliferation in a Transgenic Rat Model of Parkinson Disease by Faustine Lelan, Cécile Boyer, Reynald Thinard, Séverine Rémy, Claire Usal, Laurent Tesson, Ignacio Anegon, Isabelle Neveu, Philippe Damier, Philippe Naveilhan, Laurent Lescaudron

“…A transgenic Sprague Dawley rat bearing the A30P and A53T α-synuclein (α-syn) human mutations under the control of the tyrosine hydroxylase promoter was generated in order to get a better understanding of the role of the human α-syn mutations on the neuropathological events involved in the progression of the Parkinson’s disease (PD). …”
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Retinal Levels of Amyloid Beta Correlate with Cerebral Levels of Amyloid Beta in Young APPswe/PS1dE9 Transgenic Mice before Onset of Alzheimer’s Disease by Xi Mei, Mengxiang Yang, Lina Zhu, Qi Zhou, Xingxing Li, Zhongming Chen, Chenjun Zou

“…We measured Aβ content in the cerebrum and retina of APPswe/PS1dE9 (APP) transgenic mice with early age to investigate the correlation between cerebrum and retina. …”
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Functional Characterization of the <i>PoWHY1</i> Gene from <i>Platycladus orientalis</i> and Its Role in Abiotic Stress Tolerance in Transgenic <i>Arabidopsis thaliana</i> by Chun Ou, Zhiyu Dong, Xudong Zheng, Wenhui Cheng, Ermei Chang, Xiamei Yao

“…Here, the <i>PoWHY1</i> gene was analyzed bioinformatically using <i>P. orientalis</i> as study material, and the role of the gene against abiotic stress conditions in <i>Arabidopsis thaliana</i> was verified using transgenic technology. It was found that overexpression of <i>PoWHY1</i> increased seed germination, decreased malondialdehyde accumulation, increased proline content, and delayed the senescence process under salt stress. …”
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Studying the effect of the OsGATA rice transcription factor on salt stress tolerance in wheat by A. A. Verbitskaia, A. S. Egorova, E. A. Tsarkova, A. K. Gaponenko

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Plant expression systems for production of recombinant pharmaceutically important proteins by E. V. Deineko, A. A. Zagorskaya

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Effect of Tiaoxin Recipe on Memory Learning and Synaptic Plasticity in APP/PS1 Double Transgenic Alzheimer's Disease Mice based on αCaMKⅡ-CREB-BDNF Signal Pathway by Xiaowen WANG, Hong QIAN, Chunjuan SHEN, Yanjun LI, Haixin YUAN, Jian WANG

“…Objective:To observe the effects of Tiaoxin recipe on long-term potentiation (LTP) in hippocampal CA1 region, hippocampal alpha calcium/calmodulin-dependent kinaseⅡ (αCaMKⅡ), cyclic adenosine monophosphate response element binding protein (CREB), brain derived neurotrophic factor (BDNF), postsynaptic density 95 (PSD-95) mRNA and protein expression in hippocampal CA1 region of APP/PS1 double transgenic mice. To explore the mechanism of Tiaoxin recipe in improving memory learning and synaptic plasticity in APP/PS1 double transgenic AD mice from the point of view of αCaMKⅡ-CREB-BDNF signal pathway.Methods:A total of 54 3-month-old APP/PS1 male mice were randomly divided into the model group, the Tiaoxin recipe group and the Donepezil group according to the method of random number table, with 18 cases in each group. …”
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Quercetin Attenuates Oxidative Stress and Apoptosis in Brain Tissue of APP/PS1 Double Transgenic AD Mice by Regulating Keap1/Nrf2/HO-1 Pathway to Improve Cognitive Impairment by Meijia Cheng, Changbin Yuan, Yetao Ju, Yongming Liu, Baorui Shi, Yali Yang, Sian Jin, Xiaoming He, Li Zhang, Dongyu Min

“…Conclusion: Quercetin can improve cognitive impairment and AD-like pathology in APP/PS1 double transgenic mice, potentially related to quercetin’s activation of the Keap1/Nrf2/HO-1 pathway and reduction of cell apoptosis.…”
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Effect of salt stress on plants of wild-type <i>Nicotiana tabacum</i> L. and transformants with a choline oxidase (<i>cod</i>A) gene by I. G. Shirokikh, S. Yu. Ogorodnikova, Ya. I. Nazarova, O. N. Shupletsova

Subjects: “…transgenic tobacco…”
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Biomass and Yield in Solanum lycopersicum Expressing a Synthetic Photorespiration Pathway by Laura Dougherty, Bret Cooper, James Bunce, Bryan Vinyard, John Stommel

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Genetically modified foods: A critical review of their promise and problems by Chen Zhang, Robert Wohlhueter, Han Zhang

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CRISPR/cas9 Allows for the Quick Improvement of Tomato Firmness Breeding by Qihong Yang, Liangyu Cai, Mila Wang, Guiyun Gan, Weiliu Li, Wenjia Li, Yaqin Jiang, Qi Yuan, Chunchun Qin, Chuying Yu, Yikui Wang

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Quantitative Analysis of the Efficiency of Clonal Deletion in the Thymus by Lisa M. Spain, Leslie J. Berg

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The Continuous Improvement of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)–CRISPR-Associated Protein System Has Led to Its Highly Efficient Application in... by Wanqing Tan, Zhiyuan Wang, Liezhao Liu

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A Mouse with a Monoclonal Primary lmmunoglobulinRepertoire not Further Diversified by V-GeneReplacement by Marilia Cascalho, Denise A. Martin, Jamie Wong, Queenie Lam, Matthias Wabl, Gillian E. Wu

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Fecal microbiota transplantation attenuates Alzheimer’s disease symptoms in APP/PS1 transgenic mice via inhibition of the TLR4-MyD88-NF-κB signaling pathway-mediated inflammation by Xiang Li, Qingyong Ding, Xinxin Wan, Qilong Wu, Shiqing Ye, Yongliang Lou

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TRANSFER OF ARGOS-LIKE AND ATEXPA10 GENES INTO NONTRANSGENIC FORMS OF TOBACCO AND PHENOTYPIC EFFECTS OF THEIR CONSTITUTIVE EXPRESSION by B. R. Kuluev, E. V. Mikhaylova, A. V. Chemeris

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Alpha synuclein overexpression can drive microbiome dysbiosis in mice by Timothy R. Sampson, Zachary D Wallen, Woong-Jai Won, David G. Standaert, Haydeh Payami, Ashley S. Harms

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BvBZR1 improves parenchyma cell development and sucrose accumulation in sugar beet (Beta vulgaris L.) taproot by Ningning Li, Wei Wang, Wei Wang, Xiaotong Guo, Yaqing Sun, Guolong Li, Shaoying Zhang

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