Bactericide, Immunomodulating, and Wound Healing Properties of Transgenic Kalanchoe pinnata Synergize with Antimicrobial Peptide Cecropin P1 In Vivo by A. A. Lebedeva, N. S. Zakharchenko, E. V. Trubnikova, O. A. Medvedeva, T. V. Kuznetsova, G. A. Masgutova, M. V. Zylkova, Y. I. Buryanov, A. S. Belous

“…K. pinnata extracts (both wild-type and transgenic) did not exhibit general toxicity and accelerated wound recovery. …”
Get full text

Tension Recordings from Primary Bronchi in Acta2-GCaMP8.1-mVermilion Transgenic Mice by Qais Khalaf, Srijit Ghosh, Keith Thornbury

“…It is of interest to measure Ca2+ signals in these cells. Transgenic Acta2-GCaMP8.1-mVermilion (GCaMP) mice express a genetically encoded intracellular fluorescent Ca2+ indicator in smooth muscle cells, have been developed to facilitate the study of Ca2+. …”
Get full text

Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease by Long Fung Chau, Simon Lillico, Tanja Opriessnig, Rosemary Blake, Luc Tardy, Chen-Hsuin Lee, Scott Maxwell, Claire Warren, Elizabeth Thornton, Catherine L. Mclaughlin, Gerry McLachlan, Christine Tait-Burkard, Sarah Fletcher, Stephen Anderson, Sharon Brown, Louise Gibbard, Thomas Tzelos, Dawn MacMillan-Christensen, J. Kenneth Baillie, David A. Dorward, David J. Griffiths, Finn Grey

“…To address this, we have developed transgenic pigs expressing human ACE2 that are susceptible to SARS-CoV-2 infection. …”
Get full text

Overexpression of Cholesteryl Ester Transfer Protein Increases Macrophage-Derived Foam Cell Accumulation in Atherosclerotic Lesions of Transgenic Rabbits by Shoucui Gao, Xiaojing Wang, Daxing Cheng, Jiayan Li, Lu Li, Linwu Ran, Sihai Zhao, Jianglin Fan, Enqi Liu

“…In the study, we generated transgenic (Tg) rabbits that overexpressed the human CETP gene to examine the influence of CETP on the development of atherosclerosis. …”
Get full text

An HLA-Transgenic Mouse Model of Type 1 Diabetes That Incorporates the Reduced but Not Abolished Thymic Insulin Expression Seen in Patients by Jeffrey Babad, Riyasat Ali, Jennifer Schloss, Teresa P. DiLorenzo

“…We have developed an HLA-A∗02:01-transgenic NOD-based T1D model that is heterozygous for a functional Ins2 gene. …”
Get full text

Tolerance in TCR/Cognate Antigen Double-TransgenicMice Mediated by Incomplete Thymic Deletion andPeripheral Receptor Downregulation by Clio Mamalaki, Marianna Murdjeva, Mauro Tolaini, Trisha Norton, Phillip Chandler, Alain Townsend, Elizabeth Simpson, Dimitris Kioussis

Subjects: Get full text

Evaluation of the transmission-blocking potential of Plasmodium vivax antigen Pvg37 using transgenic rodent parasites and clinical isolates by Di Zhang, Yan Zhao, Dongyan Liu, Fei Liu, Pengbo Liu, Biying Zhang, Zifang Wu, Wanlapa Roobsoong, Sirasate Bantuchai, Sataporn Thongpoon, Piyarat Sripoorote, Meilian Wang, Liwang Cui, Yaming Cao

Subjects: Get full text

The SsDREB Transcription Factor from the Succulent Halophyte Suaeda salsa Enhances Abiotic Stress Tolerance in Transgenic Tobacco by Xu Zhang, Xiaoxue Liu, Lei Wu, Guihong Yu, Xiue Wang, Hongxiang Ma

“…The semiquantitative PCR of transgenics showed higher expression of stress-responsive genes. …”
Get full text

A New Reference Plasmid “pGMT27” Provides an Efficient Transgenic Detection Method for Flue-Cured Tobacco by Jing Yu, Xiaolian Zhang, Muhammad Faheem Adil, Bo Lei, Mengao Jia, Huina Zhao, Shizhou Yu, Jiemin Liu, Yushuang Guo, Imran Haider Shamsi

“…We concluded that using the pGMT27 plasmid as a calibrator provided a highly efficient transgenic detection method for flue-cured tobacco.…”
Get full text

Peptide-based vaccine targeting IL17A attenuates experimental spondyloarthritis in HLA-B27 transgenic rats by Tetsuya Tomita, Hiromi Rakugi, Hiroki Hayashi, Ryuichi Morishita, Jiao Sun, Yuka Yanagida, Shota Yoshida, Satoshi Baba, Akiko Tenma, Masayoshi Toyoura, Sotaro Kawabata, Takako Ehara, Ryoko Asaki, Makoto Sakaguchi, Hideki Tomioka, Munehisa Shimamura, Hironori Nakagami

“…These data showed that the peptide-based vaccine targeting IL17A alleviated the SpA phenotype in a heat-inactivated MT-induced SpA model in HLA-B27/hβ2M transgenic rats.Conclusions IL17A peptide-based vaccine may be a therapeutic option for SpA treatment.…”
Get full text

Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis. by Javier Lozano-Gerona, Aida Oliván-Viguera, Pablo Delgado-Wicke, Vikrant Singh, Brandon M Brown, Elena Tapia-Casellas, Esther Pueyo, Marta Sofía Valero, Ángel-Luis Garcia-Otín, Pilar Giraldo, Edgar Abarca-Lachen, Joaquín C Surra, Jesús Osada, Kirk L Hamilton, Siba P Raychaudhuri, Miguel Marigil, Ángeles Juarranz, Heike Wulff, Hiroto Miura, Yolanda Gilaberte, Ralf Köhler

“…Doxycycline-treated mice harboring the KCa3.1+-transgene under the control of the reverse tetracycline-sensitive transactivator (rtTA) showed 800-fold channel overexpression above basal levels in the skin and solid KCa3.1-currents in keratinocytes. …”
Get full text

Construction of Two mCherry Plasmids (pXG-mCherry) for Transgenic Leishmania: Valuable Tools for Future Molecular Analysis by Andrés Vacas, Conor Sugden, Óscar Velasco-Rodriguez, Miriam Algarabel-Olona, José Peña-Guerrero, Esther Larrea, Celia Fernández-Rubio, Paul A. Nguewa

Get full text

Effect of Electroacupuncture at Baihui Acupoint on Magnetic Resonance Spectroscopy and Spatial Learning and Memory Ability in APP/PS1 Transgenic Mice by Yingzheng ZHANG, Peiyuan ZHUO, Ruhui LIN, Lidian CHEN

“…Objective:To investigate the effects of electroacupuncture (EA) at Baihui (DU20) acupoint on learning and memory ability and¹H magnetic resonance spectroscopy (¹H-MRS) in APP/PS1 transgenic mice.Methods:A male APP/PS1 transgenic mice mated with a wild type female mice and 15 bred APP/PS1 transgenic mice identified by PCR were randomly divided into the model group (<italic>n</italic>=7) and the EA group (<italic>n</italic>=8) according to a random number table, and 8 age-matched littermates were divided into the control group. …”
Get full text

The Maize Corngrass1 miRNA-Regulated Developmental Alterations Are Restored by a Bacterial ADP-Glucose Pyrophosphorylase in Transgenic Tobacco by Ayalew Ligaba-Osena, Kay DiMarco, Tom L. Richard, Bertrand Hankoua

“…The aim of this study was to enhance carbohydrate accumulation in transgenic Nicotiana benthamiana by simultaneously expressing the maize Corngrass1 miRNA (Cg1) and E. coli ADP-glucose pyrophosphorylase (glgC), both of which have been reported to enhance carbohydrate accumulation in planta. …”
Get full text

Migration of primordial germ cells and their relationship of PGCs with sex development in transgenic germline-specific fluorescent freshwater angelfish (Pterophyllum scalare) by Wai-Kwan Chu, Shih-Chin Huang, Ching-Fong Chang, Jen-Leih Wu, Hong-Yi Gong

Subjects: Get full text

The spectrum-efficacy correlation of Kai-Xin-San for cognition of Aβ42 transgenic Drosophila and verification of its active ingredients by Jinfu Wu, Hang Sun, Yiyang Zhao, Lian Lian, Hongsheng Bian, Yong Guo, Dan Li, Lili Huang

Subjects: Get full text

Effectiveness of hCMV, mEF1a and mAct promoters on driving of foreign gene expression in transgenic zebrafish by . Alimuddin, G. Yoshizaki, O. Carman, T. Takeuchi

“…Transgen telah ditransmisikan ke ikan generasi F2 dengan mengikuti pola segregasi Mendel. …”
Get full text

PLANT GENE PROMOTERS RESPONSIVE TO PATHOGEN INVASION by O. G. Smirnova, A. V. Kochetov

Subjects: Get full text

The Effect of High Concentrations of Glufosinate Ammonium on the Yield Components of Transgenic Spring Wheat (Triticum aestivum L.) Constitutively Expressing the bar Gene by Zoltán Áy, Róbert Mihály, Mátyás Cserháti, Éva Kótai, János Pauk

“…Our results draw attention to the possibilities implied in the transgenic approaches.…”
Get full text

The genomic copy number determination of improved Cre in transgenic mice using standards derived from megaprimer PCR constructed tandem repeats by Ge Diao, Min Tian, Runbo Li, Jie Huang, Jian Han, Jianxin Guo

Subjects: Get full text