Formation of the Ventricles by Catherine A. Risebro, Paul R. Riley

“…Several genes have been identified through studies on mouse knockout and transgenic models, which have contributed to our understanding of the molecular events governing these developmental processes. …”
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Wallerian degeneration: From mechanism to disease to imaging by Ruiqi Tian, Yingying Zhou, Yuan Ren, Yisen Zhang, Wei Tang

“…However, with the wide application of transgenic mice in experiments, the latest studies have found that the mechanism of WD is related to axonal degeneration, myelin clearance and extracellular matrix. …”
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Generation of stably expressing IRF5 spliced isoform in Jurkat cells by Ashwinder Kaur, Chee-Mun Fang

“…Single-cell cloning through limiting dilution can establish a population of cells with homogenous transgene expression for exploring protein function. …”
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Swimming through asymmetry: zebrafish as a model for brain and behavior lateralization by Alessandra Gobbo, Andrea Messina, Giorgio Vallortigara

“…This review summarizes recent advances in zebrafish research on brain lateralization, highlighting how genetic tools, imaging, and transgenic methods have been used to investigate left–right asymmetries and their impact on sensory, cognitive, and social behaviors including possible links to neurodevelopmental and neurodegenerative disorders.…”
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A hypomorphic mutation in the mouse Csn1s1 gene generated by CRISPR/Cas9 pronuclear microinjection by A. V. Smirnov, T. A. Shnaider, A. N. Korablev, A. M. Yunusova, I. A. Serova, N. R. Battulin

“…Regulatory elements of the casein genes could be used to direct the expression of desired transgenes into the milk of transgenic animals. Dozens of casein alleles have been identified for goats, cows, sheep, camels and horses, and these sequence variants are associated with altered gene expression and milk protein content. …”
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Overexpression of <i>AtruLEA1</i> from <i>Acer truncatum</i> Bunge Enhanced <i>Arabidopsis</i> Drought and Salt Tolerance by Improving ROS-Scavenging Capability by Shaofeng Li, Huijing Meng, Yanfei Yang, Jinna Zhao, Yongxiu Xia, Shaoli Wang, Fei Wang, Guangshun Zheng, Jianbo Li

“…Meanwhile, the ROS level of transgenic <i>Arabidopsis</i> was significantly less than that of the WT. …”
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Impact of prior CAR T-cell therapy on mosunetuzumab efficacy in patients with relapsed or refractory B-cell lymphomas by Elise A. Chong, Elicia Penuel, Ellen B. Napier, Rachel K. Lundberg, Lihua E. Budde, Mazyar Shadman, Matthew J. Matasar, Nancy L. Bartlett, Ian W. Flinn, Francesc Bosch, Keith Fay, Andre Goy, Anita Kumar, Loretta J. Nastoupil, Michael C. Wei, Mei Wu, Shen Yin, Joseph A. Fraietta, Emeline R. Chong, Stephen J. Schuster

“…Nonresponders had a relative decrease in CAR transgene levels (n = 16; P = .04). This is, to our knowledge, the first study to assess changes in lymphocytes, T cells, and CAR transgene levels in patients treated with BsAbs after CAR-T. …”
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Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH–tanycyte unit function of polycystic ovary syndrome by Yu Wang, Yicong Wang, Yuning Chen, Wenhan Lu, Xiaoyu Tong, Jiajia Li, Wenhao Gao, Rui Huang, Wei Hu, Yi Feng

“…Functional studies in Rax-CreERT2 transgenic mice confirmed that Itgb1 plays a critical role in maintaining the balance of hypothalamic GnRH–tanycyte unit during EA treatment. …”
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Correlation of the Changes of Gray Matter Volume with Aβ Deposition and Learning and Memory Abilities in APP/PS1 Mice at Different Periods by Yuhao ZHANG, Hao JIN, Xiufeng ZHANG, Shengxiang LIANG, Weilin LIU, Jing TAO, Lidian CHEN

“…The C57-BL/6 mice were selected in the WT group, and APP/PS1 double transgenic mice were selected in the APP/PS1 group. …”
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Heterologous Expression of a Potential ‘<i>Paulownia fortunei</i>’ MYB Factor Gene, <i>PfMYB90</i>, Improves Salt and Cold Tolerance in <i>Arabidopsis</i> by Hongling Wang, Shizheng Shi, Guijie Luo, Ruifang Huang, Dezong Sui, Yunpeng Gao, Lei Wang

“…This is consistent with the results mentioned above. This transgenic technology enables <i>Arabidopsis</i> to survive under adverse environmental conditions, allowing it to maintain a relatively stable growth state despite salt accumulation and cold stress. …”
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Floridians’ Perceptions of GMOs: GMOs and Florida Citrus by Nicole M. W. Dodds, Laura M. Gorham, Joy N. Rumble

“…Among the food-related issues are concerns about consuming the products from transgenic plants, often referred to as “GMOs.” This 4-page fact sheet is intended to help Extension faculty understand public perceptions regarding the use of genetic engineering to combat citrus greening. …”
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Immunotherapeutic Strategies for Alzheimer's Disease Treatment by Beka Solomon

“…The performance of anti-amyloid-β antibodies in transgenic mice models of AD showed that they are delivered to the central nervous system, preventing and dissolving amyloid-β plaques. …”
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Floridians’ Perceptions of GMOs: GMOs and Florida Citrus by Nicole M. W. Dodds, Laura M. Gorham, Joy N. Rumble

“…Among the food-related issues are concerns about consuming the products from transgenic plants, often referred to as “GMOs.” This 4-page fact sheet is intended to help Extension faculty understand public perceptions regarding the use of genetic engineering to combat citrus greening. …”
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Visualization of the Dynamics of Gene Expression in the Living Mouse by Amy Ryan, Heidi Scrable

“…The combination of in vivo imaging and lac regulation is a powerful tool for generating conditional transgenic mice that can be screened rapidly for optimal regulation and expression patterns, and for monitoring the induction and repression of regulated genes noninvasively in the living animal.…”
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Néotène, Hybrides et Chimères by Marika Moisseeff

“…In the West, the idea of man as a creature made by God in His own image has progressively given way to a biological conception that locates humanity’s specific place and ontology between those pertaining to two distinct species: the primates that preceded humans in the course of phylogenesis, and the species that will descend from them, such as the transgenic or chimerical entities that biotechnology should allow them to create. …”
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Preclinical research models for endometrial cancer: development and selection of animal models by Yang Xue, Wei Shi, Bing Lun, Meilin Kan, Mengling Jia, Yuelin Wu, Li Yang, Li Yang

“…The use of spontaneous and chemically-induced models has decreased, with transgenic mouse and xenograft models becoming the most widely used. …”
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Valproate-Induced Model of Autism in Adult Zebrafish: A Systematic Review by Diletta Camussi, Maria Marchese, Ferdinando Nicoletti, Filippo Maria Santorelli, Asahi Ogi

“…The social behavior of the zebrafish (Danio rerio) makes this organism a valuable tool for modeling ASD in order to explore the social impairment typical of this disorder. In addition to transgenic models, exposure of zebrafish embryos to valproic acid (VPA) has been found to produce ASD-like symptoms. …”
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Effects of Antisense Oligonucleotides against C-Reactive Protein on the Development of Atherosclerosis in WHHL Rabbits by Qi Yu, Zhengcao Liu, Ahmed Bilal Waqar, Bo Ning, Xianghong Yang, Masashi Shiomi, Mark J. Graham, Rosanne M. Crooke, Enqi Liu, Sijun Dong, Jianglin Fan

“…Many controversial and contradictory results using transgenic mice and rabbits have been published but it is also unclear whether CRP lowering can be used for the treatment of atherosclerosis. …”
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Egg Microinjection for the Ladybird Beetle Harmonia axyridis by Taro Nakamura, Yuji Matsuoka, Teruyuki Niimi

“…Our step-by-step protocol is applicable to generating transgenic or genome-edited ladybird beetles, facilitating functional genetics in H. axyridis; the microinjection method should be applicable to other insect eggs.…”
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Retroviral and Lentiviral Vectors for the Induction of Immunological Tolerance by Inès Dufait, Therese Liechtenstein, Alessio Lanna, Christopher Bricogne, Roberta Laranga, Antonella Padella, Karine Breckpot, David Escors

“…Thus, three main approaches have been undertaken to induce immunological tolerance; delivery of potent immunosuppressive cytokines and other molecules, modification of intracellular signalling pathways in dendritic cells, and de-targeting transgene expression from dendritic cells using microRNA technology. …”
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