Podophyllotoxin mediates hepatic toxicity via the C5a/C5aR/ROS/NLRP3 and cGMP/PKG/mTOR axis in rats based on toxicological evidence chain (TEC) concept by phosphoproteomic analysis by Chuanxin Liu, Xiaobin Huang, Jiao Kong, Xuejiao Li, Yuming Wang, Fangfang Zhang, Jiajia Duan

“…In conclusion, this study comprehensively revealed the underlying mechanisms of PPT-induced hepatotoxicity using the TEC concept. This approach transforms fragmented toxicity indicators into systematic evidence of toxicity, presenting a hierarchical progression of toxicity evidence and avoiding data accumulation in natural drug toxicology. …”
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Fálétí’s Philosophical Sensibility by Adeshina Afolayan

“…These authors were all verbal stylists of a high order; they transformed the literary language, moving away from Fágúnwà’s rolling cadences to a more demotic, supple prose that successfully caught the accents of everyday life (2004, 368). …”
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Rome à la campagne : les décors en pierre de la villa de la Grande Boussue à Nouvelles (Mons, Belgique) by Catherine Coquelet, Roland Dreesen, Éric Goemaere, Éric Leblois, Marie-Thérèse Raepsaet-Charlier

“…At the beginning of the 2nd century a very large aristocratic residence was built with a 1.5 km long aquaduct and baths. After a final transformation and embellishment at the end of the 2nd or beginning of the 3rd century, this main building reached a length of almost 300 metres. …”
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Editorial by Jörg Tremmel, Markus Rutsche

“…The third paper, authored by Rajeev Sadanandan (Health Systems Transformation Platform, India), talks about the lessons that can and should be drawn from child immunisations. …”
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WRF-Chem simulations of snow nitrate and other physicochemical properties in northern China by X. Wang, X. Wang, T. Che, T. Che, X. Ruan, S. Yue, S. Yue, J. Wang, J. Wang, C. Zhao, C. Zhao, C. Zhao, L. Geng, L. Geng, L. Geng

“…These results illustrate the ability of WRF-Chem to simulate snow properties including concentrations of reservoir species in northern China, and in the future, we will incorporate snow nitrate photolysis in the model, exploring the emissions of snow NO<span class="inline-formula">_<i>x</i></span> from nitrate photolysis and the impacts on local and regional atmospheric chemistry and air pollutant transformations.</p>…”
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Global, regional, and national trends in drug use disorder mortality rates across 73 countries from 1990 to 2021, with projections up to 2040: a global time-series analysis and mod... by Soeun Kim, Hayeon Lee, Selin Woo, Hyeri Lee, Jaeyu Park, Tae Kim, Guillaume Fond, Laurent Boyer, Masoud Rahmati, Lee Smith, Guillermo F. López Sánchez, Elena Dragioti, Christa J. Nehs, Jinseok Lee, Hyeon Jin Kim, Jiseung Kang, Dong Keon Yon

“…Our analysis also identified associations between DUD mortality rates and several log-transformed parameters, including Human Development Index (β, 14.92; p < 0.0001), Socio-demographic Index (β, 11.80; p < 0.0001), reverse Gender Gap Index (β, −12.02; p < 0.0001), and Gini coefficient (β, −1.84; p < 0.0001). …”
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Authority and Moral Conflicts in the Films of Adébáyọ Fálétí: Àfọ̀njá, Gáà, Ṣawo Ṣẹ̀gbẹ̀rì and the Yorùbá Cosmopolis by Olayinka Agbetuyi

“…I argue that such pains and pangs of transformation are not unique to Yorùbá society but mirror similar political evolutions in other societies such as Rome and Greece. …”
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Les fours « à pain » dans les Gaules et les Germanies (ve s. av. J.-C.-ve s. apr. J.-C.), un regard technique by Nicolas Monteix, Camille Noûs

“…One of the 26 baking trials carried out between April 2016 and May 2019 is described in detail in order to track the different phases occurring as dough transforms into bread. The principle is to bake by heat accumulation, wherein the fuel is removed from the oven once a temperature of about 550°C is reached, as indicated by the whitening of the oven walls: the soot no longer deposits but is immediately incinerated. …”
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A propos de l'extension complète des doigts longs et des 4 derniers orteils des primates by J Norbert Kuhlmann

“…Les muscles interosseux, à l'exception de ceux des Hominoïdes, ne sont ni palmaires, ni dorsaux, mais indifférenciés puisqu'ils ne possèdent qu'un seul tendon terminal. La transformation des extenseurs profonds en extenseurs propres de la main accroît chez les Hominoïdes l'autonomie du deuxième et du cinquième doigt. …”
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Alimentation et gestion de l’eau sur la colline de Fourvière à Lyon : les aménagements hydrauliques, la ville et ses monuments by Aldo Borlenghi, Éric Leroy

“…Conversely, it might have received its water supply from the Yzeron aqueduct at the time when the complex was transformed during the reigns of Tiberius and Claudius. …”
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Wetland birds of middle Vistula River during breeding season: the impact of human activities on the distribution, abundance and richness of species by Dariusz Bukaciński, Monika Bukacińska, Arkadiusz Buczyński

“…There are, however, fragments of several kilometres, where people transformed the Vistula River in a more noticeable way (Table 1). …”
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A Meta-Synthesis of the Integrated Model of Customer Value co-Destruction and Value co-Creation by Zohreh Dehdashti Shahrokh, Vahid Nasehifar, Mohammad Reza Karimi Alavijeh, Yazdan Rahmatabadi

“…One of the cases where value co-creation has been transformed into co-destruction can be considered when women request a car, in which cases the driver is also considered a woman. …”
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不同年资神经内科医师对数智化诊疗的认知、态度及功能需求现状调查 A Survey on the Cognition, Attitude, and Functional Requirements of Digital Intelligent Diagnosis and Treatment Among Neurologists of Different Se... by 邳靖陶1*，尹伟2，3*，宋晓微1，武海岩3，梁怡凡1，高策舒1，魏宸铭1，桑振华1，安志明3，江燕敏3，吴雅婷1，牟婧宇1，赵心怡1，陈乐1，武剑1，4，5（*第一作者） (PI Jingtao1*, YIN Wei2,3*, SONG Xiaowei1, WU Haiyan3, LIANG Yifan1, GAO Ceshu1, WEI Chenming1, SANG Zhenhua1, AN Zhiming3, JIANG Yanmin3, WU Yating1, MU Jingyu1, ZHAO Xinyi1, CHEN Le1, WU Jian1,4,5 (*contributed equally) )

“…The future development of AI should focus on the transparency and practicality of the technology to facilitate the intelligent transformation of the medical model.…”
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不同温度烫制红油辣椒的风味研究 Flavor of chili oil poured at different temperatures by 张峰轶，王浩文，田浩，刘琨，王传明 ZHANG Fengyi, WANG Haowen, TIAN Hao, LIU Kun, WANG Chuanming

“…In conclusion, pouring temperature has a significant effect on the formation and transformation of the flavor of chili oil. By selecting raw material and controlling the pouring temperature, the flavor of chili oil can be more accurately regulated. …”
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Pierre et carrières dans la Saintonge antique : identification, usages et diffusion by Jacques Gaillard, Egle Conforto

“…The briefly described geomorphological history, underscores the Pyrenean orogeny, a major event which transformed the Aquitaine basin of the secondary era into the current sedimentary plateau. …”
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Carbon footprint reduction practices in the Olympic Games: a policy mobility approach by Wesselia Isa Ngoenha

“…Unlike traditional nation-state-centric approaches, policy mobility emphasizes the role of non-state actors, international networks of experts, and global organizations in policy diffusion and transformation (Cochrane & Ward, 2012). In the context of mega-events such as the Olympic Games, it explains how sustainability-related practices and ideas travel between editions of the Games, influencing local policies while being reconfigured according to specific contexts. …”
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Factors affecting the design of the management dashboard framework with an emphasis on the components of human resources productivity by Hassan Barmaki, Farshad Faezy Razi, Ehtesham Rashidi

“…It resulted to counting 40 indicators in 4 areas of human resources of the General Department of Education, Human Resource Planning and Administrative Transformation (management training and development, human resource planning, human resource supply, and human resource research) and how to calculate them.Research methodologyThe research method is applicable in terms of purpose, qualitative in terms of execution method, and cross-sectional survey in terms of nature. …”
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Presenting the model of social entrepreneurship in the development of rural tourism in the target villages of Gilan province by Fatemeh Doozandeh Ziabari, hamed fallah tafti, Mir Mohammad Asadi, Mahdi Basouli

“…The most important advantage of promoting entrepreneurship in tourism can be said that since the tourism sector is one of the country's economic sectors and in fact, one of the axes of the country's economic development, thinkers and policy makers have paid special attention to the development of entrepreneurship in tourism and solving its problems (Hesam et al, 2015).Tourism social entrepreneurshipSheldon et al, (2017) have defined the tourism social entrepreneurship as follows: a process that uses tourism to create innovative solutions for urgent social, environmental and economic problems in the destination by mobilizing ideas, capacities, resources and social agreements, from inside or outside the destination, for its sustainable social transformation (Sheldon et al, 2017).Mansoori et al, (2024) investigated the presentation of the model of factors affecting the development of scientific tourism in Iran's higher education system. …”
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Natural Resource Rent and Financial Development: Testing Financial Resource Curse Hypothesis in Iran by Majid Aghaei, Mahdieh Rezagholizadeh, mohammad abdi, rawa mosavi

“…The results of estimating the overall financial development index, which is obtained by combining stock market development and banking development, highlight the importance of financial integration and the utilization of the entire financial system's capacity to transform resource rents into a resource blessing.Top of Form Discussion and Conclusion: Based on the empirical results, the hypothesis of the presence of resource cures in the banking sector in Iran was confirmed, given the significant positive relationship between banking sector development and natural resource abundance during the study period. …”
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INTERNATIONAL FORUM OF AMERICAN SOCIETY FOR ENGINEERING EDUCATION by Vasily Ivanov, Yulia Ziyatdinova

“…In terms of how to teach, Purdue promotes new modes of teaching and transforms the majority of courses into hybrid teaching. …”
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