Recommendations for the diagnosis and treatment of anti-neutrophil cytoplasmic autoantibody associated vasculitis by Enrique Morales, Iñigo Rúa-Figueroa, José Luis Callejas Rubio, Ana Ávila Bernabéu, Ricardo Blanco Alonso, María C. Cid Xutgla, Gema Fernández Juárez, Natalia Mena-Vázquez, Juan José Ríos Blanco, Joaquín Manrique Escola, F. Javier Narváez García, Bernardo Sopeña, Luis F. Quintana Porras, Susana Romero-Yuste, Roser Solans Laqué

“…In recent years, a better knowledge of B lymphocyte function and the role of complement inhibition has transformed the course of this disease while minimising treatment-related adverse effects.This multidisciplinary document of recommendations is based on the consensus of three scientific societies (Internal Medicine, Nephrology and Rheumatology) and on the best available evidence on diagnosis, treatment and follow-up of patients with ANCA-associated vasculitis, including some special situations. …”
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RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melan... by Sara Egea‐Rodriguez, Renáta Váraljai, Thierry M. Nordmann, Restuan Lubis, Manuel Philip, Florian Rambow, Alexander Roesch, Michael Flaig, Susanne Horn, Raphael Stoll, Fang Zhao, Annette Paschen, Bert Klebl, Ian D. Hickson, Dirk Schadendorf, Matthias Mann, Iris Helfrich

“…Abstract Background Cancer immunotherapy has transformed metastatic cancer treatment, yet challenges persist regarding therapeutic efficacy. …”
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Innovación en sueño by Laura Vigil, Toni Zapata, Andrea Grau, Marta Bonet, Montserrat Montaña, María Piñar

“…Despite these obstacles, AI and Big Data have the potential to transform medical care for sleep disorders, improving both diagnosis and treatment adherence, provided regulatory and cultural barriers are overcome.…”
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Changes of Narrative: Osvald Sirén’s Photographic Modeling of Modern Research on Chinese Garden by Jiuwen GU, Yuanfeng SHI, Shan JIA

“…At the same time, these images of gardens with great detail content have formed a strong set of garden narratives, which in turn influence the perspective of garden research — a spatially compressed perspective with multiple details superimposed on each other, and a perspective that transforms spatial protagonists and garden narratives, which has begun to subconsciously influence the direction of garden research. …”
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基于ChatGLM急性缺血性卒中大血管闭塞的识别与诊断 Identification and Diagnosis of Large Vessel Occlusion in Acute Ischemic Stroke Based on ChatGLM by 宋晓微1，尹伟2，李佳褀3，魏宸铭1，王玥明1，邳靖陶1，陈乐1，高策舒1，马为之3，武剑1，4 (SONG Xiaowei1, YIN Wei2, LI Jiaqi3, WEI Chenming1, WANG Yueming1, PI Jingtao1, CHEN Le1, GAO Ceshu1, MA Weizhi3, WU Jian1,4 )

“…The diagnostic accuracy rates for large vessel occlusion using zero-shot learning, zero-shot learning + chain-of-thought, generative pre-trained transformer+chain-of-thought, few-shot learning, and few-shot learning + chain-of-thought were 36.1%, 52.1%, 73.0%, 72.6%, and 75.1%, respectively. …”
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Exploring Future Pandemic Preparedness Through the Development of Preventive Vaccine Platforms and the Key Roles of International Organizations in a Global Health Crisis by Jihee Jeon, Eunyoung Kim

“…Moreover, international vaccine support organizations should play key roles in setting the direction of global networking and preparing for international vaccine support programs to address the limitations of previous pandemic responses. As a result, by transforming future pandemic threats from unpredictable crises to surmountable challenges, it is expected to strengthen global health systems and reduce the social and economic burden of emerging infectious diseases in the long term.…”
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Combined Effects of Humic Acid-Modified Magnetic Biochar and AMF on the Properties of Saline-Alkali Soil and Photosynthetic Parameters of Muskmelon by ZHANG Yating, LOU Xueyi, WU Jiarui, LIU Hongyuan, YE Binyu, XIAO Jiamin, LI Jiameng, MIAO Yining, CHEN Xinyan, LIU Yilin, TAN Yuyu, WANG Zhichao, LIU Peng

“…Moreover, nutrients such as Fe2+, Mg2+ and nitrogen could form a transformation cycle between biochar and fungi, thus improving nutrient use efficiency. …”
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Characteristics of Traditional Human Settlement Landscapes on Bedrock Islands in Guangdong Based on the “Ao” Unit by Ying PAN, Linxi CHEN, Ying SHI

“…ObjectiveThe objective of this research is to contribute to the strategic goal of transforming China into a strong maritime nation by enhancing the understanding and management of the ocean, and by fostering innovation in marine science and technology. …”
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Exemples d’habitats aristocratiques sur les sites des rues Eugène-Desteuque et Ponsardin à Reims/Durocortorum by Magalie Cavé, Stéphane Sindonino, Sabine Groetembril

“…The colonnade was built atop the former southern wall of the semi-buried gallery, which was thus transformed to become a stylobate platform. The abandonment is dated to around 375-380 - 410-420 AD. …”
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Gas drainage and utilization in coal mines in China: History, technological advances, and prospects by Guofu LI, Chao LI, Bichuan ZHANG, Yun XU, Zheng WANG, Xianjun ZHOU

“…Since the beginning of the 21st century, the understanding of gas in coal mines has transitioned from simple disasters to disasters associated with resources, gradually achieving the transformation from gas pumping to gas drainage. In combination with the differences in geological conditions of gas in varying mining areas, three typical gas drainage modes have been formed: the surface-underground combined gas drainage mode through “four-zone linkage” in the Jincheng mining area in Shanxi Province (the new Jincheng mode), the protective layer mining mode for broken-soft and low-permeability coal seams in the Huainan-Huaibei area in Anhui Province (the Huainan-Huaibei mode), and the hydraulically enhanced permeability mode of the Songzao mining area in Chongqing City (the Songzao mode). …”
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The Edge Odd Graceful Labeling of Water Wheel Graphs by Mohammed Aljohani, Salama Nagy Daoud

“…This labeling is defined as a bijection <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>g</mi><mo>:</mo><mi>E</mi><mo>(</mo><mi>G</mi><mo>)</mo><mo>→</mo><mo>{</mo><mn>1</mn><mo>,</mo><mn>3</mn><mo>,</mo><mo>…</mo><mo>,</mo><mn>2</mn><mi>m</mi><mo>−</mo><mn>1</mn><mo>}</mo></mrow></semantics></math></inline-formula>, from which an injective transformation is derived, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mi>g</mi><mo>*</mo></msup><mo>:</mo><mi>V</mi><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow><mo>→</mo><mrow><mo>{</mo><mn>1</mn><mo>,</mo><mn>2</mn><mo>,</mo><mn>3</mn><mo>,</mo><mo>…</mo><mo>,</mo><mn>2</mn><mi>m</mi><mo>−</mo><mn>1</mn><mo>}</mo></mrow></mrow></semantics></math></inline-formula>, from the rule that the image of <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>u</mi><mo>∈</mo><mi>V</mi><mo>(</mo><mi>G</mi><mo>)</mo></mrow></semantics></math></inline-formula> under <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mi>g</mi><mo>*</mo></msup></semantics></math></inline-formula> is <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mo>∑</mo><mrow><mi>u</mi><mi>v</mi><mo>∈</mo><mi>E</mi><mo>(</mo><mi>G</mi><mo>)</mo></mrow></msub><mi>g</mi><mrow><mo>(</mo><mi>u</mi><mi>v</mi><mo>)</mo></mrow><mspace width="0.277778em"></mspace><mi>mod</mi><mspace width="0.277778em"></mspace><mrow><mo>(</mo><mn>2</mn><mi>m</mi><mo>)</mo></mrow></mrow></semantics></math></inline-formula>. …”
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Torrefaction of bamboo pellets using a fixed counterflow multibaffle reactor for renewable energy applications by W. Hidayat, B.A. Wijaya, B. Saputra, I.T. Rani, S. Kim, S. Lee, J. Yoo, B.B. Park, L. Suryanegara, M.A.R. Lubis

“…According to a Fourier-transform infrared analysis, torrefaction caused extractive and hemicellulose degradation and lignin increase. …”
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Associations between milk infrared-predicted plasma biomarkers of stress resilience and fertility in dairy cattle: Insights for enhancing breeding programs and herd management by Alessio Cecchinato, Hugo Toledo-Alvarado, Lucio Flavio Macedo Mota, Vittoria Bisutti, Erminio Trevisi, Riccardo Negrini, Sara Pegolo, Stefano Schiavon, Luigi Gallo, Giovanni Bittante, Diana Giannuzzi

“…The blood metabolites (15 blood biomarkers related to hepatic damage and function, oxidative stress, inflammation, and innate immunity) were predicted using milk Fourier-transform mid-infrared (MIR) spectroscopy. A gradient boosting machine approach with leave-one-batch-out cross-validation (R2 range from 0.45 to 0.82) was implemented to an independent calibration database of 1,367 lactating cows reared in 5 herds. …”
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Evolution, Characteristics and Inspirations of Management Zoning for National Parks in the United States by Zhenwei ZHANG, Hanyue XIAO, Yankang MAO

“…In addition, this research analyzes the nine characteristics of the management zoning for national parks in the United States: 1) Functional attribute of zoning — transform from functional zoning to comprehensive control zoning; 2) functional characteristics of zoning — most zones are similar to China’s main functional zone, rather than the restricted red line zone; 3) functional goal of zoning — strive to achieve the dual balance of “protection − utilization”; 4) zoning policies are of flexibility and complete; 5) zoning is based on the dynamic adaptive management theory; 6) zoning should be supported by a more comprehensive and systematic policy system; 7) zoning must be based on a scientific and rigorous policy system; 8) different designation areas and autonomous zoning composed its rigid and flexible frame; 9) zoning may be deduced through the comparison of multiple scenaro.ConclusionChina’s national park zoning should be regarded as a technical method relying on management rules, for which the system development should be strengthened. …”
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Accessible moderate-to-severe obstructive sleep apnea screening tool using multidimensional obesity indicators as compact representations by Xiaoyue Zhu, Chenyang Li, Xiaoting Wang, Zhipeng Yang, Yupu Liu, Lei Zhao, Xiaoman Zhang, Yu Peng, Xinyi Li, Hongliang Yi, Jian Guan, Shankai Yin, Huajun Xu

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ADMINISTRATIVE PREREQUISITES FOR FINANCIAL MANAGEMENT AND MARKETING OF SMALL BUSINESSES AT THE REGIONAL LEVEL by Natalia Koval, Oksana Kubai, Natalia Germaniuk

“…In the context of expanding economic independence at the regional level, the role of business in regional development, particularly in terms of financial management and marketing, is undergoing a transformation. The financial management and marketing of small business entities is focused on the management of financial resources and financial relations that arise between business entities during the process of financial resource movement.…”
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Global, regional, and national epidemiology of childhood neuroblastoma (1990–2021): a statistical analysis of incidence, mortality, and DALYsResearch in context by Jusen Nong, Cheng Su, Changhua Li, Congjun Wang, Wei Li, Yong Li, Peng Chen, Yanqiang Li, Zihao Li, Xinjin She, Zuxin Yuan, Sentian Liu, Chao Chen, Qian Liao, Yige Luo, Bo Shi

“…Trends were assessed using Joinpoint regression models to compute the annual percent change (APC) and log-transformed linear regression models to calculate the estimated average annual percentage change (EAPC). …”
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Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus) by Junyu Yan, Kai Luo, Bo Wang, Jiaxin He, Can Li, Jiang Zhou, Wenhao Lai, Xin Zhou, Jingwei Ye, Mingzhu Pan, Yingbing Su, Weihua Gao, Kai Guo, Chengmin Zhao

“…The level of tgf-β (transforming growth factor beta), il-10 (interleukin 10), caspase3, caspase7, caspase9, occludin, zo-1 (zonula occludens-1), zo-2, claudin-12, claudin-15a, claudin-15b in the intestine of the 0.10 % group significantly increased compared with the control group (P < 0.05). …”
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Determination of the physicochemical and microbiological quality of buffalo milk in the south of lake Maracaibo by Luis Álvarez, Alexis Zambrano, Datty Rosales-Zambrano

“… The determination of quality parameters in the food industry is a critical point in the transformation process in aspects such as safety and quality attributes required by the market for a product, the cheese making industry does not escape this. …”
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响应面优化氯化胆碱-丙三醇体系提取芝麻蛋白工艺条件 "Response surface optimization of the extraction process conditions for sesame protein using choline chloride-glycerol system"... by 曹培换1，张晨霞1，刘燕2，马宇翔1，刘华敏1，郑永战1，3 "CAO Peihuan1，ZHANG Chenxia1，LIU Yan2，MA Yuxiang1， LIU Huamin1，ZHENG Yongzhan1,3"

“…To improve the comprehensive utilization rate of protein in sesame cake and meal, a by-product of sesame oil, sesame protein was extracted from sesame meal using choline chloride -glycerol (molar ratio 1∶ 3) system (deep eutectic solvent, DES), the extraction process conditions were optimized through single factor experiments and response surface methodology, and the functional characteristics of sesame protein extracted under the optimal conditions were analyzed. Fourier transform infrared spectroscopy and scanning electron microscopy were used to characterize the structure of sesame protein. …”
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