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Transforming Growth Factor-Beta and Matrix Metalloproteinases: Functional Interactions in Tumor Stroma-Infiltrating Myeloid Cells
Published 2014-01-01“…Transforming growth factor-beta (TGF-β) is a pleiotropic factor with several different roles in health and disease. …”
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Evaluation of Transforming Growth Factor Beta-1 Gene 869T/C Polymorphism with Hypertension: A Meta-Analysis
Published 2011-01-01“…Association between transforming growth factor beta-1 gene (TGFB1) 869T/C polymorphism and hypertension has been widely evaluated, yet with conflicting results. …”
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GDF15-mediated enhancement of the Warburg effect sustains multiple myeloma growth via TGFβ signaling pathway
Published 2025-01-01Subjects: Get full text
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Diagnostic Effectiveness of Transforming Growth Factor Beta 1 in Assessing the Risk of Developing Graft Dysfunction in Liver Recipient Children
Published 2019-06-01Subjects: Get full text
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A novel TGFBR2 mutation causes Loeys-Dietz syndrome in a Chinese infant: A case report
Published 2025-01-01Subjects: Get full text
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Transforming Growth Factor Beta Family: Insight into the Role of Growth Factors in Regulation of Fracture Healing Biology and Potential Clinical Applications
Published 2015-01-01“…The transforming growth factor beta (TGF-β) family forms a group of three isoforms, TGF-β1, TGF-β2, and TGF-β3, with their structure formed by interrelated dimeric polypeptide chains. …”
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Serum Concentrations of Transforming Growth Factor-Beta 1 in Predicting the Occurrence of Diabetic Retinopathy in Juvenile Patients with Type 1 Diabetes Mellitus
Published 2013-01-01“…In the present study, we have decided to evaluate if serum transforming growth factor-beta 1 (TGF-β1) concentrations may have diagnostic value in predicting the occurrence of diabetic retinopathy (DR) in juvenile patients with type 1 diabetes mellitus (T1DM). …”
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Natural antifibrosis potential of anthocyanin in Ipomoea batatas against Transforming Growth Factor beta Type II receptor by in silico ADMET and molecular docking study
Published 2025-01-01“…Anthocyanins derived from I. batatas can suppress the action of Transforming Growth Factor beta Type II Receptor (TGFβRII) to prevent fibrosis progression. …”
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Fibrosis in PCLS: comparing TGF-β and fibrotic cocktail
Published 2025-01-01Subjects: Get full text
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Polymorphisms and dental age in non-syndromic cleft lip and palate: a cross-sectional study
Published 2025-01-01“…Genomic DNA was extracted from buccal cells, and SNPs in Epidermal Growth Factor (EGF) – rs4444903 and rs2237051, Epidermal Growth Factor Receptor (EGFR) – rs2227983 –, Transforming Growth Factor Beta 1 (TGFB1) – rs1800470 and rs4803455 –, and Transforming Growth Factor Beta Receptor 2 (TGFBR2) – rs3087465 – were genotyped by real-time polymerase chain reactions using the TaqMan assay. …”
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The Inter-Relationship of Periostin, TGFβ, and BMP in Heart Valve Development and Valvular Heart Diseases
Published 2011-01-01“…Recent studies have suggested an important role for periostin and transforming growth factor beta (TGFβ) and bone morphogenetic protein (BMP) ligands in heart valve formation and valvular heart diseases. …”
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The four-dimensional Kirschner-Panetta type cancer model: How to obtain tumor eradication?
Published 2018-09-01“…In this paper we examine ultimate dynamics of the four-dimensional model describing interactions between tumor cells, effector immune cells, interleukin -2 and transforming growth factor-beta. This model was elaborated by Arciero et al. and is obtained from the Kirschner-Panetta type model by introducing two various treatments. …”
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Desmoplastic reaction in the microenvironment of head and neck and other solid tumors: the therapeutic barrier
Published 2025-02-01“…DR promotes epithelial-mesenchymal transition and cancer cell invasion through CAF-mediated extracellular matrix remodeling and signaling pathways such as transforming growth factor-beta. DR also affects bone invasion and chemotherapy resistance by modulating stromal responses. …”
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Role of the TGF-β cytokine and its gene polymorphisms in asthma etiopathogenesis
Published 2025-01-01“…Transforming growth factor beta (TGF-β) is a pluripotent cytokine expressed by all cells of the human body which plays important roles in maintaining homeostasis and allowing for proper individual development. …”
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Nucleus pulposus cell network modelling in the intervertebral disc
Published 2025-01-01“…Model validation through published studies replicated pro-catabolic and pro-anabolic shifts, emphasizing the roles of transforming growth factor beta (TGF-β) and interleukin-1 receptor antagonist (IL-1Ra) in ECM regulation. …”
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Penggunaan Tetes Telinga Serum Autologous dengan Amnion untuk Penutupan Perforasi Membran Timpani
Published 2012-07-01“…Sel epitel amnion memproduksi faktor pertumbuhan seperti fibroblast growth factor dan transforming growth factor beta. Faktor pertumbuhan akan membantu komunikasi antara epitel dan sel fibroblast stroma untuk menekan proliferasi dan diferensiasi jaringan fibrosis. …”
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The Role of the TGF-β Coreceptor Endoglin in Cancer
Published 2010-01-01“…Endoglin (CD105) is an auxiliary membrane receptor of transforming growth factor beta (TGF-β) that interacts with type I and type II TGF-β receptors and modulates TGF-β signaling. …”
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Mathematical insights on psoriasis regulation: Role of Th1 and Th2 cells
Published 2018-05-01“…Interferon gamma ( $\mbox{IFN}-{γ}$ ), Transforming growth factor beta ( $\mbox{TGF}-β$ ) and Tumor necrosis factor alpha ( $\mbox{TNF}-α$ ) etc. …”
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Oxidative Stress in Diabetic Nephropathy with Early Chronic Kidney Disease
Published 2016-01-01“…Alterations in the redox state in DN are caused by the persistent state of hyperglycemia and the increase in advanced glycation end products (AGEs) with ability to affect the renin-angiotensin system and the transforming growth factor-beta (TGF-β), producing chronic inflammation and glomerular and tubular hypertrophy and favoring the appearance of oxidative stress. …”
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