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341
Identification and Validation of TEAD Family’s Prognostic Effects and Immune Microenvironment Regulations in Glioma
Published 2024-01-01“…The TEA domain transcription factor (TEAD) family proteins are the ultimate effector molecules of the Hippo pathway. …”
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342
Modulation of first-passage time for bursty gene expression via random signals
Published 2017-09-01“…The stochastic nature of cell-specific signal molecules (such as transcription factor, ribosome, etc.) and the intrinsic stochastic nature of gene expression process result in cell-to-cell variations at protein levels. …”
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343
Advances in the relationship between AP-1 and tumorigenesis, development and therapy resistance
Published 2025-01-01“…Abstract Activating protein 1 (AP-1) is a transcription factor composed of several protein families, Jun proteins and Fos proteins are the components of AP-1. …”
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344
Unveiling cell-type-specific microRNA networks through alternative polyadenylation in glioblastoma
Published 2025-01-01“…The constructed networks of microRNA-transcription factor-target genes provide insights into the cellular mechanisms influencing cancer cell survival and therapeutic resistance. …”
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345
Follicular Thyroid Carcinoma Metastatic to the Kidney: Report of a Case with Cytohistologic Correlation
Published 2015-01-01“…Immunohistochemistry revealed positivity for thyroglobulin and thyroid transcription factor 1, consistent with metastatic follicular thyroid carcinoma (FTC). …”
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346
Decreases in mRNA by an siRNA Complex Do not Alter Blood Pressure in Mice
Published 2012-03-01“…CASZ1 is a zinc finger transcription factor that controls apoptosis and cell fate and suppresses neuroblastoma tumor growth by reprogramming gene expression, like a tumor suppressor. …”
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347
Pax6 regulates neuronal migration and cell proliferation via interacting with Wnt3a during cortical development
Published 2025-02-01“…Abstract The paired box 6 (Pax6) gene encodes a highly conserved transcription factor, involved in the development of eyes, brain, and endocrine glands. …”
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348
Biosynthesis of the Essential Fatty Acid Oxidation Cofactor Carnitine Is Stimulated in Heart and Liver after a Single Bout of Exercise in Mice
Published 2018-01-01“…Liver and heart were removed under the same conditions for measurement of carnitine biosynthesis enzymes (liver butyrobetaine hydroxylase, γ-BBH; heart trimethyllysine dioxygenase, TMLD), organic cation transporter-2 (OCTN2, carnitine transporter), and liver peroxisome proliferator-activated receptor-alpha (PPARα, transcription factor for γ-BBH and OCTN2 synthesis). In exercised mice, FC levels in plasma decreased while heart and liver OCTN2 protein expressed increased, reflecting active uptake of FC. …”
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349
Folic Acid Is Able to Polarize the Inflammatory Response in LPS Activated Microglia by Regulating Multiple Signaling Pathways
Published 2016-01-01“…Inducible NO synthase (iNOS), nuclear transcription factor-kappa B (NF-κB) p65, MAPKs protein, and suppressors of cytokine signaling (SOCS)1 and SOCS3 were analyzed by western blotting. …”
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350
Explore the Role of the rs1801133-PPARG Pathway in the H-type Hypertension
Published 2022-01-01“…Both rs1801133 mutation on Methylenetetrahydrofolate reductase (MTHFR) gene and transcription factor peroxisome proliferator-activated gamma (PPARG) have been associated with plasma homocysteine (Hcy) levels and hypertension. …”
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351
The Role of Bovine Amniotic Membrane and Hydroxyapatite for the Ridge Preservation
Published 2024-01-01“…The combination of bovine amniotic membrane and hydroxyapatite has shown promise as a scaffold material containing growth factors that can stimulate osteogenic-related factors such as bone morphogenetic protein 2 (BMP2), Runt-related transcription factor 2 (RUNX2), and osteocalcin. This stimulation leads to collagen production and osteoblast proliferation, resulting in new bone formation. …”
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352
Role of the Mucin-2 and Kaiso genes in the social behavior of mice
Published 2015-12-01“…The Kaiso gene encodes a transcription factor that is expressed both in the brain and in the intestine. …”
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353
SOX5-Null Heterozygous Mutation in a Family with Adult-Onset Hyperkinesia and Behavioral Abnormalities
Published 2017-01-01“…SOX5 encodes a conserved transcription factor implicated in cell-fate decisions of the neural lineage. …”
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354
Lineage tracing studies suggest that the placenta is not a de novo source of hematopoietic stem cells.
Published 2025-01-01“…We found that the Runx1 transcription factor, which is required to generate HSPCs from HECs, is not expressed by mouse placental ECs. …”
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355
STK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8+ T-Cells
Published 2020-01-01“…STK3 promoted the migration of CD8+ T-cells by activating nuclear transcription factor κB (NF-κB) signaling. STK3 is a potential predictor of OC. …”
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356
Aryl Hydrocarbon Receptor Deficiency in an Exon 3 Deletion Mouse Model Promotes Hematopoietic Stem Cell Proliferation and Impacts Endosteal Niche Cells
Published 2016-01-01“…The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor belonging to the Per-Arnt-Sim (PAS) family of proteins. …”
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357
Bioinformatic Prediction of Novel microRNAs Encoded in Krüppel-like Factor 4 Gene
Published 2024-02-01“…Krüppel-like factor 4 (KLF4) is a transcription factor that has different regulatory functions, and it plays a role in various cellular processes. …”
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358
The Critical Role of Bach2 in Shaping the Balance between CD4+ T Cell Subsets in Immune-Mediated Diseases
Published 2019-01-01“…The transcription factor Bach2 which is predominantly expressed in B and T lymphocytes represses the expression of genes by forming heterodimers with small Maf and Batf proteins and binding to the corresponding sequence on the DNA. …”
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359
Antitumor Activities of Aqueous Cinnamon Extract on 5637 Cell Line of Bladder Cancer through Glycolytic Pathway
Published 2022-01-01“…For evaluating of aqueous extract of Cinnamon effect on glycolysis, the gene expression of epidermal growth factor receptor 2 (ErbB2), heat shock protein transcription factor1 (HSF1), and lactate dehydrogenase A (LDHA), as well as protein levels of HSF1 and LDHA, LDH activity, glucose consumption, and lactate production, were measured. …”
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360
Application of Mesoporous Silica Nanoparticle-Chitosan-Loaded BMP-2 in the Repair of Bone Defect in Chronic Osteomyelitis
Published 2022-01-01“…In the BMSC test, we found that Chi-MSN could better promote their activity and osteogenesis, and the expression of osteogenesis-related genes (runt-related transcription factor 2 (RUNX-2), osteopontine (OPN), alkaline phosphatase (ALP), and osteopontine (OCN)) in the Chi-MSN group was higher. …”
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