Showing 181 - 200 results of 997 for search '"transcription factor"', query time: 0.05s Refine Results
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    Editorial: Epigenetics and genomic causality in development and chromatin research by Ellen V. Rothenberg, Ute Deichmann

    Published 2025-02-01
    Subjects: “…chromatin interaction with transcription factors…”
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    Article
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    An Overview of the Role of Innate Lymphoid Cells in Gut Infections and Inflammation by Silvia Sedda, Irene Marafini, Michele M. Figliuzzi, Francesco Pallone, Giovanni Monteleone

    Published 2014-01-01
    “…Specifically, ILCs1 express the transcription factor T-bet and secrete T helper type-1- (Th1-) related cytokines, ILCs2 are dependent on the transcription factor RORα and express Gata-3 and the chemokine receptor homologous molecule (CRTH2) and produce Th2-related cytokines, and ILCs3 express the transcription factor RORγt and synthesize interleukin- (IL-) 17, IL-22, and, under specific stimuli, interferon-γ. …”
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  15. 195

    The use of graphics accelerators to detect functional signals in the regulatory regions of prokaryotic genes by O. V. Vishnevsky, A. V. Bocharnikov, A. A. Romanenko

    Published 2016-01-01
    “…Various methods for identification of significant contextual signals are widely used to search for transcription factor binding sites and to identify the structural and functional organization of regulatory regions. …”
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    Article
  16. 196

    Genomic and Computational Analysis of Novel SNPs in TNP1 Gene Promoter Region of Bos indicus Breeding Bulls by Kashif Hameed Anjum, Asif Nadeem, Maryam Javed, Hafiz Ishfaq Ahmad, Amjad Riaz, Wasim Shehzad, Jahanzaib Azhar, Muhammad Fahad Bhutta

    Published 2022-01-01
    “…The computational analyses indicated that the polymorphisms inside the promoter sequence results in an added HNF-1 transcription factor binding site. In contrast, the other variations may remove the naturally occurring SRF transcription factor binding site. …”
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    Article
  17. 197

    Multi-locus CRISPRi targeting with a single truncated guide RNA by Molly M. Moore, Siddarth Wekhande, Robbyn Issner, Alejandro Collins, Anna J. Cruz, Yanjing V. Liu, Nauman Javed, Salvador Casaní-Galdón, Jason D. Buenrostro, Charles B. Epstein, Eugenio Mattei, John G. Doench, Bradley E. Bernstein, Noam Shoresh, Fadi J. Najm

    Published 2025-02-01
    “…Here, we develop a CRISPRi-based approach for multi-locus screening of putative transcription factor binding sites with a single truncated guide. …”
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  18. 198

    PGC-1α activation to enhance macrophage immune function in mycobacterial infections. by Joel R Frandsen, Zhihong Yuan, Brahmchetna Bedi, Zohra Prasla, Seoung-Ryoung Choi, Prabagaran Narayanasamy, Ruxana T Sadikot

    Published 2025-01-01
    “…Mitochondrial transcription factor A (TFAM) is a protein essential for mitochondrial DNA (mtDNA) genome stability, integrity, and metabolism. …”
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  19. 199

    The Transcriptional Network Structure of a Myeloid Cell: A Computational Approach by Jesús Espinal-Enríquez, Daniel González-Terán, Enrique Hernández-Lemus

    Published 2017-01-01
    “…So far, there is a small set of curated known interactions between transcription factors and their downstream genes. Here, we built a transcription factor network for human monocytic THP-1 myeloid cells based on the experimentally curated FANTOM4 database where nodes are genes and the experimental interactions correspond to links. …”
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  20. 200

    PPARγ as a Potential Target to Treat Airway Mucus Hypersecretion in Chronic Airway Inflammatory Diseases by Yongchun Shen, Lei Chen, Tao Wang, Fuqiang Wen

    Published 2012-01-01
    “…These findings suggest that PPARγ is a novel target in the treatment of AMH and that further work on this transcription factor may lead to new therapies for chronic airway inflammatory diseases.…”
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