Angiotensin-(1-7) and Alamandine Promote Anti-inflammatory Response in Macrophages In Vitro and In Vivo by Melissa de Carvalho Santuchi, Miriane Fernandes Dutra, Juliana Priscila Vago, Kátia Maciel Lima, Izabela Galvão, Fernando Pedro de Souza-Neto, Mario Morais e Silva, Aline Cristina Oliveira, Flávia Carvalho Bittencourt de Oliveira, Ricardo Gonçalves, Mauro Martins Teixeira, Lirlândia Pires Sousa, Robson Augusto Souza dos Santos, Rafaela Fernandes da Silva

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Molecular Mechanisms of Phthalate-Induced Hepatic Injury and Amelioration by Plant-Based Principles by Lalit Kumar Singh, Rashmi Pandey, Nikhat Jamal Siddiqi, Bechan Sharma

“…This review presents a comprehensive and updated account of the chemical, biochemical, immunological, and toxicological properties of phthalates, along with novel plant-based therapeutic strategies to mitigate the phthalate-induced adverse effects on living systems.…”
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Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock by Shuxian Zhang, Minglu Yang, Tao Xu, Qiongxian Yan, Allan Degen, Xiaoling Zhou

“…However, the pharmacological and toxicological effects of some compounds have not been well documented, and further investigations of the bioactive compounds are needed. …”
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Severe Diltiazem Poisoning Treated with Hyperinsulinaemia-Euglycaemia and Lipid Emulsion by Nadine Monteiro, Joana Silvestre, João Gonçalves-Pereira, Camila Tapadinhas, Vitor Mendes, Pedro Póvoa

“…Approximately 17 hours after drug intake, hyperinsulinaemia-euglycaemia with lipid emulsion therapy was initiated, followed by progressive haemodynamic recovery within approximately 30 minutes. The toxicological serum analysis 12 h after drug ingestion revealed a diltiazem serum level of 4778 ng/mL (therapeutic level: 40–200 ng/mL). …”
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Differential Susceptibility to Particulate Matter-Induced Cardiac Remodeling and Senescence: A Comparative Study in Young and Aged Mice by Dunia Waked, Gabriel Henrique Rodella Guedes, Raissa Macedo, Paulo Hilário Nascimento Saldiva, Mariana Matera Veras, Ana Paula Cremasco Takano

“…Background: Epidemiological and toxicological studies have shown that inhalation of particulate matter (PM), a major component of air pollution, is associated with the development of cardiovascular diseases (CVDs). …”
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Use and legislation of Glyphosate in Mexico: healthcare, healthy environment and drinking water access. by Arizbeth Pérez-Martínez, Arely Vergara-Castañeda, Kytzia Esmeralda Mercado-Moreno, Christian Benítez-Núñez, Alma Cossette Guadarrama Muñoz

“…Glyphosate is an agrochemical compound used as a main substance in the formulation of pesticides having a low toxicological level, and it is currently the most widely used herbicide worldwide. …”
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Kinetic Study of Biodangerous Methylmercury Degradation under Various Light Conditions by Yutao Zhang, Xia Chen, Qixia Jiang, Xiaojuan Zhang, Qiuyun Zhang

“…Methylmercury (MeHg) has remarkable toxicological effects on humans, plants, and other lives in the environment, which may restrict the comprehensive utilization of biomass source in view of possibly forming biohazardous waste. …”
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Development of a New Sequential Extraction Procedure of Nickel Species on Workplace Airborne Particulate Matter: Assessing the Occupational Exposure to Carcinogenic Metal Species by Catalani Simona, Fostinelli Jacopo, Gilberti Maria Enrica, Orlandi Francesca, Magarini Riccardo, Paganelli Matteo, Madeo Egidio, De Palma Giuseppe

“…Due to the specific toxicological properties of the different Ni species, there is a growing interest about the availability of analytical methods that allow specific risk assessment, particularly related to exposure to the Ni species classified as carcinogenic. …”
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Development and Validation of LC-MS/MS for Analyzing Potential Genotoxic Impurities in Pantoprazole Starting Materials by Yuyuan Chen, Song Wu, Qingyun Yang

“…To date, no suitable method has yet been developed for PGI separation and quantification at the threshold of toxicological concern levels. In this study, a sensitive and reliable liquid chromatography-tandem mass spectrometry method was developed and validated for the quantitative analysis of six PGIs in DMBZ according to the guidelines of the International Council for Harmonization (ICH). …”
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Renal Evaluation in Common Variable Immunodeficiency by Giovany Gomes Capistrano, Gdayllon Cavalcante Meneses, Fernanda Macedo de Oliveira Neves, Renata de Almeida Leitão, Alice Maria Costa Martins, Alexandre Braga Libório

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Occurrence and Risk Assessment of Tetracycline Residues in Layer Eggs in Haryana, India by Khushbu Bishnoi, Pallavi Moudgil, Deepak Soni, Vijay J. Jadhav

“…The risk assessment based on the per capita availability of eggs in Haryana revealed that the current levels of residues in eggs pose no significant toxicological effects on the consumer’s health. The residues exceeding MRL indicate nonprudent use of antibiotics in veterinary practices, which could lead to the emergence of antibiotic resistance. …”
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The Acetone Extract of Sclerocarya birrea (Anacardiaceae) Possesses Antiproliferative and Apoptotic Potential against Human Breast Cancer Cell Lines (MCF-7) by Nicoline Fri Tanih, Roland Ndip Ndip

“…The current study was aimed to further study some pharmacological and toxicological properties of the plant to scientifically justify its use. …”
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O istotnych kontrowersjach wokół oceny zagrożeń środowiska i jego naprawy by Konrad Gałuszko

“…Subsequently to the above were discussed: the criticism of some misconceptions and the evolution of scientists. opinions about derivations of the greenhouse effect, toxicity and carcinogenesis criteria, evidence supporting the threshold dose versus the linear hypothesis at the evaluation of harmful environmental effects, examples of ecological utopia assuming a possibility of “life in the world without toxins”, the consequences of acts of law created with the idea, untrustworthy examples of alleged hazards, Poland’s law delay with the assimilation of the new toxicological and carcinogenesis evidence, DDT application dilemma concerned with the latter, the acceptance of the threshold dose also for radioactivity, the latest news about ravages of the Chernobyl catastrophe, the author’s belief in better cooperation of humanists, ecophilosophers, scientists and mass media people to create sensible social attitudes of the public in the face of the ecological and civilization crisis.…”
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General and Electrophysiological Toxic Effects of Manganese in Rats following Subacute Administration in Dissolved and Nanoparticle Form by Edina Horváth, Zsuzsanna Máté, Szabolcs Takács, Péter Pusztai, András Sápi, Zoltán Kónya, László Nagymajtényi, András Papp

“…After 3 and 6 weeks oral, or 3 weeks oral plus 3 weeks intratracheal, exposure, general toxicological, and electrophysiological tests were done. …”
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The Health Impact of Cocoa from Cultivation to the Formation of Biogenic Amines: An Updated Review by Antonello Paparella, Maria Schirone, Clemencia Chaves López

“…In addition to polyphenols, other compounds of interest are biogenic amines, due to their role and potential toxic effects on human health. Based on toxicological data and recent research on the complex relationship between biogenic amines and cocoa fermentation, setting limits or standards for biogenic amines in cocoa and chocolate could help ensure product safety. …”
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Analysis of the effectiveness of premedication in preventing early adverse reactions to antivenom serum from 2017 to 2021: A cohort study by Gustavo Abud Priedols, Jonas Alher Meira Alves, Jordana Meirelles de Oliveira, Jéssica Vertuan Rufino, Edmarlon Girotto, Camilo Molino Guidoni

“…This is a cohort study conducted with data from the Londrina Information and Toxicological Assistance Center (CIATox-Londrina) at the University Hospital of the State University of Londrina (HU-UEL), which included patients treated with AVS between January/2017 and December/2021. …”
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Comprehensive toxicity assessment of silver nanoparticles on Bacteria, human vein endothelial cells, and Caenorhabditis Elegans by Bircan Dinç

“…In HUVEC cells, the IC50 was found to be 38 μg/mL, with cellular uptake increasing proportionally to concentration after 48 h.This study highlights the unique toxicological profile of AgNPs at low concentrations across multiple biological systems, emphasizing the importance of careful consideration for their safe use in biomedical and environmental applications.…”
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Arsenic accumulation and reproductive toxicity in freshwater snail (Pomacea canaliculata) by Xiaoyang Bi, Zhifei Shi, Dongqin Li, Wenhui Zhan, Zhixiong Wang, Huashou Li, Benliang Zhao, Guikui Chen

“…This study aimed to investigate the tissue-specific accumulation patterns of arsenic (As) and the potential toxicological effects of As on the oviposition of a globally distributed aquatic invertebrate, the apple snail (Pomacea canaliculata). …”
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ENVIRONMENTAL SYSTEM ENGINEERING (ESE): MODELING AND OPTIMIZATION OF A TEXTILE EFFLUENT DISCOLORATION PROCESS BY SORPTION by CARMEN ZAHARIA

“…In this system, environmental modeling and process optimization acts together for solving problems with environmental systems, especially for minimizing pollution, or eco-toxicological effects. The present paper proposes the study of modeling and optimization of an environmental system (i.e. textile wastewater treatment system based on sorption onto indigene peat) for its discoloration (consequently, decreasing of color, organic and inorganic loads of effluent discharged in aquatic receptor, or inside reused). …”
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Safety of mineral salt containing potassium and magnesium as a novel food pursuant to Regulation (EU) 2015/2283 by EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Helle Katrine Knutsen, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Harry J. McArdle, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Monika Neuhäuser‐Berthold, Morten Poulsen, Miguel Prieto Maradona, Josef Rudolf Schlatter, Alexandros Siskos, Henk vanLoveren, Emanuela Turla, Karen Ildico Hirsch‐Ernst

“…Taking into account the composition and the nature of the NF, the Panel considers that no toxicological studies with the NF are required. The Panel concludes that the NF (i.e. a mineral salt containing potassium and magnesium) is safe under the proposed conditions of use.…”
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