Treatment of Acquired von Willebrand Syndrome and Prevention of Bleeding Postautologous Stem Cell Transplant during Severe Pancytopenia with IVIG by Behyar Zoghi, Paul Shaughnessy, Roger M. Lyons, Richard Helmer, Carlos Bachier, C. Frederick LeMaistre

“…Patients with myeloma and Acquired von Willebrand Syndrome (AVWS) undergoing autologous stem cell transplant (ASCT) are at significant risk of bleeding due to the profound thrombocytopenia, low Factor VIII levels, fever, and toxicities associated with the preparative regimen. …”
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Ribosomal Alteration-Derived Signals for Cytokine Induction in Mucosal and Systemic Inflammation: Noncanonical Pathways by Ribosomal Inactivation by Yuseok Moon

“…Although the primary effect of ribosomal inactivation in cells is the functional inhibition of global protein synthesis, early responsive gene products including proinflammatory cytokines are exclusively induced by toxic stress in highly dividing tissues such as lymphoid tissue and epithelia. …”
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How to Obtain an Aldicarb Application Permit for Florida Cotton or Peanut by Zane J. Grabau, Ethan Carter, Libbie Johnson, Jay Ferrell, Dale Dubberly, Tamara James

“… This publication is intended to guide growers through the process of applying for a free permit to use aldicarb, an insecticide/nematicide subject to particular restrictions because of its highly toxic nature and concerns about groundwater contamination when it is improperly applied. …”
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Natural Products for Managing Landscape and Garden Pests in Florida by Eileen A. Buss, Sydney G. Park Brown

“… This publication describes “natural” pesticides: alternatives that are usually less toxic to non-target organisms and the environment and that, when used correctly, can be effective substitutes for synthetic products. …”
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Pulmonary Nodules After Leflunomide Therapy in Rheumatoid Arthritis: A Case Report by Mahdiye Abiyarghamsari, Arman Ahmadzadeh

“…This case highlights the need for vigilance regarding potential pulmonary toxicity in RA patients receiving leflunomide and underscores the importance of prompt recognition and management of drug‐induced complications.…”
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Baiting the Nine-banded Armadillo by Holly K. Ober, Lucas W. DeGroote, Russell F. Mizell

“…There are no repellents, toxicants, or fumigants registered for use with them. …”
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Comparing adsorption of bisphenol A and similar compounds in aqueous solution by syringe filters by Nathaniel Godby, Alfred Conklin

“…Bisphenol A and similar compounds are being extensively examined for their toxicity. This study serves to characterize common syringe filters and their effects on analytical results. …”
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Climate Change and the Occurrence of Harmful Microorganisms in Florida’s Ocean and Coastal Waters by Karl Havens

“…These include algae that form noxious or toxic blooms, including red tides, and bacteria and other pathogens. …”
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Baiting the Nine-banded Armadillo by Holly K. Ober, Lucas W. DeGroote, Russell F. Mizell

“…There are no repellents, toxicants, or fumigants registered for use with them. …”
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The EPA Conventional Reduced Risk Pesticide Program by Frederick M. Fishel

“…Riskier conventional alternatives are those pesticides EPA deems as having neurotoxic, carcinogenic, reproductive, and developmental toxicity, or groundwater contamination effects. It serves as a means to ensure that reduced risk pesticides enter the channels of trade and are available to growers as soon as possible. …”
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Removal of Copper(II) from Aqueous Solutions by Flotation Using Limestone Fines as the Sorbent and Oleic Acid as the Surfactant by S.E. Ghazy, S.E. Samra, S.M. El-Morsy

“…The removal of toxic copper(II) from aqueous solutions was investigated using limestone fines (LS), which are inexpensive and widespread over the globe, as the effective inorganic sorbent with oleic acid (HOL) as the surfactant. …”
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Régulation, verrous technologiques et transition écologique : le cas des formaldéhydes by Nicolas Béfort

“…The present change towards the use of renewable resources is activating production regimes in which economic actors are trying to use as an opportunity the social contestation of toxic molecules. In this context, our aim is to analyze the use of formaldehyde, an emblematic and carcinogenic molecule widely used in the production of resins and adhesives.Starting with a review of the regulation literature analyzing innovation, we discuss here the 'evolutionist theory of environmental innovations' in order to highlight an analytical framework that aims to analyze from a historical perspective the dynamics of acquiring knowledge. …”
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The Combined Effect of Garlic (Allium sativum) and Turmeric (Curcuma longa) Extracts to Reduce the Adverse Effects of Aflatoxin B1 in Rats by Hadi Sarir, Saeedeh Zakerian, masood didarkhah

“…These findings suggest that the combination of garlic and turmeric extracts may have a synergistic protective effect against aflatoxin B1 toxicity. In examining the ALP factor, there was a statistically significant difference between the treatments of garlic or turmeric extract and the combination of these two extracts. …”
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Anticancer activity of Ilex khasiana, a rare and endemic species of holly in Northeast India, against murine lymphoma by Charles Lalnunfela, Pawi Bawitlung Lalthanpuii, Hmar Tlawmte Lalremsanga, Zothansiama, Chhaihlo Lalmuansangi, Mary Zosangzuali, Nachimuthu Senthil Kumar, Tochhawng Lalhriatpuii, Kholhring Lalchhandama

“…An alkylated phenol, 2,6-di-tert-butylphenol, was the predominant compound. Acute toxicity test indicated that the plant extract was non-toxic even at the highest dosage tested, i.e., 2000 mg/kg body weight. …”
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Enhanced Interleukin 6 Trans-Signaling Modulates Disease Process in Amyotrophic Lateral Sclerosis Mouse Models by Carol Milligan, Dale O. Cowley, William Stewart, Alyson M. Curry, Elizabeth Forbes, Brian Rector, Annette Hastie, Liang Liu, Gregory A. Hawkins

“…Intense research efforts have provided insight into unique neuroanatomical regions, specific neuronal populations and genetic associations for ALS and other neurodegenerative diseases; however, the experimental results also suggest a convergence of these events to common toxic pathways. We propose that common toxic pathways can be therapeutically targeted, and this intervention will be effective in slowing progression and improving patient quality of life. …”
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Propionate metabolism in a human pathogenic fungus: proteomic and biochemical analyses by Luiz Paulo Araújo Santos, Leandro do Prado Assunção, Patrícia de Souza Lima, Gabriel Brum Tristão, Matthias Brock, Clayton Luiz Borges, Mirelle Garcia Silva-Bailão, Célia Maria de Almeida Soares, Alexandre Melo Bailão

“…Paracoccidioides spp. cells also induce transcripts/enzymes of the methylcitrate cycle (MCC), a pathway responsible for propionyl-CoA metabolism. Propionyl-CoA is a toxic compound formed during the degradation of odd-chain fatty acids, branched chain amino acids and cholesterol. …”
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CC-96673 (BMS-986358), an affinity-tuned anti-CD47 and CD20 bispecific antibody with fully functional fc, selectively targets and depletes non-Hodgkin’s lymphoma by Dan Zhu, Haralambos Hadjivassiliou, Catherine Jennings, David Mikolon, Massimo Ammirante, Sharmistha Acharya, Jon Lloyd, Mahan Abbasian, Rama Krishna Narla, Joseph R. Piccotti, Katie Stamp, Ho Cho, Kandasamy Hariharan

“…To date, the advancement of CD47-targeted modalities is hindered by the ubiquitous expression of the target, often leading to rapid drug elimination and hematologic toxicity including anemia. To overcome those challenges a bispecific approach was taken. …”
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Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion by Mirjana Babić Leko, Vera Župunski, Jason Kirincich, Dinko Smilović, Tibor Hortobágyi, Patrick R. Hof, Goran Šimić

“…The proposed molecular mechanisms by which C9orf72 repeat expansions induce neurodegenerative changes are C9orf72 loss-of-function through haploinsufficiency, RNA toxic gain-of-function, and gain-of-function through the accumulation of toxic dipeptide repeat proteins. …”
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Chemoimmunotherapy as induction treatment in concurrent chemoradiotherapy for patients with nasopharyngeal carcinoma stage IVa by Kun-Peng Wu, Qing-Qing Li, Xu-Qiang Luo, Xiao-Xi Wang, Yan-Zhen Lai, Dan Tian, Hong-cheng Yang, Xue-Ling Wei, Lan-Ying Wang, Qiu-Ming Li, Dao Zhu, Si-Jie Chen, Yang-Si Li

“…This study aimed to evaluate the efficacy, toxicity, and survival outcomes of induction chemoimmunotherapy in patients with locoregionally advanced NPC.Methods This study analyzed 50 patients with stage IVa NPC between January 2020 and December 2023 in our hospital. …”
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Identification of key chromium resistance genes in Cellulomonas using transcriptomics by Hongmei Sun, Yongdong Li, Shengchao Gao, Guangchuan Shi, Lianbin Cao, Xinya Li, Tong Li, Tongbiao Li, Mingcheng Wang, Enzhong Li, Junhe Liu, Hongxia Ni, Yi Chen, Ying Liu

“…Cellulomonas fimi Clb-11 can reduce high toxic Cr(VI) to less toxic Cr(III), and transcriptomics was used to reveal the key Cr(VI) uptake and reduction genes of C. fimi Clb-11 in this study. …”
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