Heme Oxygenase-1: A Critical Link between Iron Metabolism, Erythropoiesis, and Development by Stuart T. Fraser, Robyn G. Midwinter, Birgit S. Berger, Roland Stocker

“…Linked with this pressure is the necessity of the embryo to obtain and transport iron, synthesize hemoglobin, and then dispose of the potentially toxic heme via the stress-induced protein heme oxygenase-1 (HO-1, encoded by Hmox1 in the mouse). …”
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2003 Handbook of Employment Regulations Affecting Florida Farm Employers and Workers: Right-to-Know Law [State] by Leo C. Polopolus, Michael T. Olexa, Fritz Roka, Carol Fountain

“… The Right-to-Know Law establishes Florida standards of safety for certain employers who manufacture, produce, use, apply, or store toxic substances. This is EDIS document FE413, a publication of the Department of Food and Resource Economics, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL. …”
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Intralipid Therapy for Inadvertent Peripheral Nervous System Blockade Resulting from Local Anesthetic Overdose by Ihab Kamel, Gaurav Trehan, Rodger Barnette

“…Inadvertent intravascular injection of local anesthetics and/or the use of excessive doses have been the most frequent causes of local anesthetic systemic toxicity (LAST). Furthermore, excessive doses of local anesthetics injected locally into the tissues may lead to inadvertent peripheral nerve infiltration and blockade. …”
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Florida Solid and Hazardous Waste Regulation Handbook: Emergency Planning and Community Right-to-Know Act (EPCRA) by Michael T. Olexa, Aaron Leviten, Kelly Samek

“… The Emergency Planning and Community Right-to-Know Act (EPCRA) was passed in 1986 to improve emergency response to accidental releases of toxic and/or hazardous chemicals into the environment. …”
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Treatment of Ethylene Glycol Poisoning with Oral Ethyl Alcohol by B. Achappa, D. Madi, T. Kanchan, N. K. Kishanlal

“…The ill effects are primarily caused by its toxic metabolites: glycolic acid and oxalic acid. …”
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GENETIC PREDISPOSITION TO HEMATOLOGIC MALIGNANCIES IN CHILDHOOD AND ADOLESCENCE by Francesco Fabozzi, Angela Mastronuzzi

“…The recognition of a germline mutation in a patient affected by a hematologic malignancy allows for a tailored treatment approach in order to minimize toxicities, and informs the donor selection for hematopoietic stem cell transplantation as well as the comorbidities evaluation and surveillance strategies. …”
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Immunotherapy of Brain Cancers: The Past, the Present, and Future Directions by Lisheng Ge, Neil Hoa, Daniela A. Bota, Josephine Natividad, Andrew Howat, Martin R. Jadus

“…For some patients, immunotherapy has worked for them while not showing long-term toxicity. In this paper, we will trace the history of immunotherapy for brain cancers. …”
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Isolation and Characterization of Antitumor Alkaloid from Poppy Capsules (Papaver somniferum) by Ibrahim Bulduk, Fulya Taktak

“…Noscapine, a phthalideisoquinoline alkaloid derived from opium, has been used in the treatment of various cancer types. Its low-toxicity profile has increased attention to this alkaloid. …”
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2003 Handbook of Employment Regulations Affecting Florida Farm Employers and Workers: Right-to-Know Law [State] by Leo C. Polopolus, Michael T. Olexa, Fritz Roka, Carol Fountain

“… The Right-to-Know Law establishes Florida standards of safety for certain employers who manufacture, produce, use, apply, or store toxic substances. This is EDIS document FE413, a publication of the Department of Food and Resource Economics, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL. …”
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Clinical features of the course of Hirschsprung’s disease in newborns and infants with consideration of the extent of colonic aganglionosis by V.P. Prytula, O.O. Kurtash, V.F. Rybalchenko, S.F. Hussaini

“…The severity of the course and late diagnosis are the main reasons for the appearance of severe complications of HD in newborns and infants - hypotrophy (67.70%), HD-associated enterocolitis (65.22%), toxic megacolon (3.31%) and anemia (49.89%). The research was carried out in accordance with the principles of the Declaration of Helsinki. …”
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Protective Effects of Sanyar Prebiotic on Immunity and Tissue Changes of Common Carp (Cyprinus carpio) Exposed to CuSO4 Stress by Ramezan Rajani, Mohammad Farhangi, Hojjatallah Jafaryan, Hossein Adineh, Maryam Alizadeh

“…At the end of the experimental period, the fish were exposed to acute toxicity of Cu (0.1 m/l) for 96 hours. Gill, kidney, and liver tissue samples were collected and evaluated after 96 hours. …”
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Efficacy of Anti-Cancer Immune Responses Elicited Using Tumor-Targeted IL-2 Cytokine and Its Derivatives in Combined Preclinical Therapies by Sahar Balkhi, Giorgia Bilato, Andrea De Lerma Barbaro, Paola Orecchia, Alessandro Poggi, Lorenzo Mortara

“…Preclinical and clinical studies highlight reduced toxicity and enhanced anti-tumor efficacy, overcoming TME-driven immune suppression. …”
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Risks to human and animal health from the presence of bromide in food and feed by EFSA Scientific Committee, Susanne Hougaard Bennekou, Ana Allende, Angela Bearth, Josep Casacuberta, Laurence Castle, Tamara Coja, Amélie Crépet, Thorhallur Halldorsson, Laurentius (Ron) Hoogenboom, Helle Knutsen, Konstantinos Koutsoumanis, Claude Lambré, Søren Nielsen, Dominique Turck, Antonio Vicent Civera, Roberto Villa, Holger Zorn, Vasileios Bampidis, Jacqueline Castenmiller, Marie‐Christine Chagnon, Bruce Cottrill, Keyvin Darney, Jürgen Gropp, Secundino Lopez Puente, Martin Rose, Marco Vinceti, Maria Bastaki, Petra Gergelová, Luna Greco, Matteo Lorenzo Innocenti, Judit Janossy, Anna Lanzoni, Andrea Terron, Diane Benford

“…Abstract The European Commission mandated EFSA to assess the toxicity of bromide, the existing maximum residue levels (MRLs), and possible transfer from feed into food of animal origin. …”
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High-level biosynthesis and purification of the antimicrobial peptide Kiadin based on non-chromatographic purification and acid cleavage methods by Liangjun Zheng, Fengyi Yang, Chen Wang, Muhammad Zafir, Zishuo Gao, Pilong Liu, Fatma A. El-Gohary, Xin Zhao, Huping Xue

“…Despite their potential, the physiological toxicity of AMPs to host cells significantly hampers their biosynthetic production. …”
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Growth and viability of juvenile humpback grouper (Cromileptes altivelis) supplemented with inorganic and organic selenium by Muhaimin Hamzah, Muhammad Agus Suprayudi, Nur Bambang Priyo Utomo, Wasmen Manalu

“…On the contrary, supplementation of selenomethionine up to 4 mg Se/kg did not show any signs of toxicity and the survival was on 86.11 to 97.22%. Feed efficiency, protein retention, lipid retention, and Se retention indicated that a dosage of 4 mg Se/kg selenomethionine supplementation was the best dosage. …”
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Role of polyethylene glycol to alleviate lead stress in Raphanus sativus by Muhammad Sajid, Shakil Ahmed, Rehana Sardar, Aamir Ali, Nasim Ahmad Yasin

“…The continuous contamination of heavy metals (HMs) in our ecosystem due to industrialization, urbanization and other anthropogenic activities has become a serious environmental constraint to successful crop production. Lead (Pb) toxicity causes ionic, oxidative and osmotic injuries which induce various morphological, physiological, metabolic and molecular abnormalities in plants. …”
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The effect of ozone exposure on the release of eicosanoids in guinea-pig BAL fluid in relation to cellular damage and inflammation by H. J. M. Van Hoof, F. J. Zijlstra, H-P. Voss, I. M. Garrelds, J. A. M. A. Dormans, L. Van Bree, A. Bast

“…We hypothesized that depending on the O3 exposure protocol, mainly either an oxidant damage or an inflammation will determine the O3 toxicity. We compared two different ozone exposure protocols: an acute exposure (3 ppm 2 h) for studying the oxidant damage and an exposure (1 ppm 12 h) where an inflammatory component is also probably involved. …”
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Anti-Inflammatory Activities of Some Plants of Genus Alpinia: Insights from In Vitro, In Vivo, and Human Studies by Yuliawati KM, Febriyanti RM, Sumiwi SA, Levita J

“…These plants did not show toxicity toward numerous normal cell lines (RAW 264.7, IEC-6, HepG2, MT-4, NIH-3T3, Vero cells, human peripheral blood mononuclear cells, and HaCaT) but were toxic to cancer cell lines (HT29). …”
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Malyngamide F Possesses Anti-Inflammatory and Antinociceptive Activity in Rat Models of Inflammation by Zhuocheng Li, Lei Zhang, Zhichao Zhao

“…Methods. The possible toxicity of Maltoamide F was evaluated by an acute toxicity test. …”
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In vivo imaging and pharmacokinetics of percutaneously injected ultrasound and X-ray imageable thermosensitive hydrogel loaded with doxorubicin versus free drug in swine. by Jose F Delgado, Ayele H Negussie, Nicole A Varble, Andrew S Mikhail, Antonio Arrichiello, Tabea Borde, Laetitia Saccenti, Ivane Bakhutashvili, Joshua W Owen, Robert Morhard, John W Karanian, William F Pritchard, Bradford J Wood

“…Intratumoral injections often lack visibility, leading to unpredictable outcomes such as incomplete tumor coverage, off-target drug delivery and systemic toxicities. This study investigated an ultrasound (US) and x-ray imageable thermosensitive hydrogel based on poloxamer 407 (POL) percutaneously delivered in a healthy swine model. …”
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