Comparative Study of <i>Phytolacca</i> Species Through Morphological, Chloroplast Genome, and Phylogenetic Analysis by Sumin Jeong, Yeseul Kim, Heewon Ji, Jun-Ho Song, Inkyu Park

“…However, because of their potent toxicity, it is essential to distinguish these species. …”
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Pathogenic and therapeutic role of bile acids at reflux-gastritis by T. L. Lapina, I. M. Kartavenko, V. T. Ivashkin

“…They can increase endocellular concentration of calcium which is responsible for toxic effects of bile acids as a secondary messenger. …”
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Innovative approach to Pb (II) removal using zinc-based MOFs-derived carbon: In-depth analysis of adsorption mechanisms, isotherms, thermodynamics, and kinetics by Samira Ahmadzadeh, Alireza Hemmati

“…Water contamination by lead is a critical environmental problem due to its toxicity and persistence in industrial effluents. The removal of lead ions from aqueous solutions has become a significant concern for environmental and public health. …”
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Encapsulation of paclitaxel into date palm lipid droplets for enhanced brain cancer therapy by Amal YOUSFAN, Nour MOURSEL, Abdulsamie HANANO

“…Abstract Paclitaxel, a powerful anticancer drug, is limited by its poor water solubility and systemic toxicity, which hinder its effectiveness against aggressive brain tumors. …”
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Cytotoxic evaluation of a mixture of four commonly used pesticides on mammalian cell lines by Prudence Agnandji, Eugène S. Attakpa, Fabrice Cazier

“…The cytotoxicity was compared to a quantitative structure-activity relationship for baseline toxicity, and chemicals were confirmed as baseline toxicants in this cell line. …”
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Degradation of PCDD/Fs from incineration of waste at low temperatures for resource utilization of fly ash by Songxuan CHEN, Hao WANG, Dongwei ZHANG, Mengxiao LAN, Zhi SUN, Yuping GAO, Hongbin CAO

“…This includes polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), which are among the most toxic substances to humans and other living organisms. …”
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Strategies to Enhance Nanocrystal Formulations for Overcoming Physiological Barriers Across Diverse Routes of Administration by Yanamadala Y, Muthumula CMR, Khare S, Gokulan K

“…However, the challenges related to toxicity, scale-up, and clinical translation still need further attention. …”
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In Vitro Vitamin K3 Effect on Conjunctival Fibroblast Migration and Proliferation by I. Pinilla, L. B. Izaguirre, F. J. Gonzalvo, E. Piazuelo, M. A. Garcia-Gonzalez, A. I. Sanchez-Cano, F. Sopeña

“…Vitamin K3 2 mg/L or higher doses inhibit wound healing repair, exhibiting cellular toxicity at 4 and 6 mg/L.…”
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Complex System Analysis of Blumeria graminis f.sp. tritici Isolates Collected in Central Hebei Province, China by Qingping Zhou, Lingli Li, Long Wang

“…In this study, using wheat seedling culture in vitro, the physiological races of wheat powdery mildew in central Hebei province were identified, and the population toxicity frequency was analyzed. The results were as follows: (1) 36 strains were purified and 20 physiological races were identified. …”
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Synthesis and Characterization of 5-Fluoroacil Loaded Calcium Carbonate Nanoparticles for Targeted Cancer Therapy by Kshidan Marim Abdullah Salem, Mohamed Ahmed Ibrahim, Kim Wei Chan, Md Zuki Abu Bakar, Noorjahan Banu Alitheen, Mohammed Alsubbi, Ahmad Faizal Abdull Razis, Norsharina Ismail

“…1736142025"> Chemotherapy is often limited by its systemic toxicity and lack of specificity, necessitating the development of targeted drug delivery systems that can enhance therapeutic efficacy while minimizing adverse effects. …”
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Organic UV-filters and freshwater organisms: data gaps impede a robust retrospective environmental risk assessment by Alexandra Kroll, Cornelia Kienle, Marion Junghans

“…Therefore, new assessment methods (NAMs) are recommended, including the use of fish cell lines for acute toxicity testing and alternatives for the assessment of chronic toxicity.…”
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Morphological characterization of biominerals from five multicellular marine algae species by A. M. Zakharenko, M. A. Nawaz, V. V. Chaika, I. V. Zemchenko, T. Yu. Orlova, A. A. Begun, R. V. Romashko, A. N. Galkina, A. A. Karabtsov, G. Chung, K. S. Golokhvast

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Antifungal Activity and Major Bioactive Compounds of Water Extract of Pangium edule Seed against Aspergillus flavus by Kharisma I. Listyorini, Harsi D. Kusumaningrum, Hanifah N. Lioe

“…The water extracts showed a moderate toxicity with LC50 of 100-500 μg/mL, determined by the brine-shrimp toxicity test. …”
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Bio-computational modeling, POM analysis and molecular dynamic simulation for novel synthetic quinolone and benzo[d][1,3]oxazine candidates as antimicrobial inhibitors by Doaa A. Elsayed, Mohamed E. Abdu, Mohammed A. Marzouk, Elsayed M. Mahmoud, Walaa H. El-Shwiniy, Andrew M. Spring, Wesam S. Shehab

“…This indicates that these compounds may possess some level of selectivity and reduced toxicity towards normal cells, suggesting potential for further exploration as antibacterial agents with a safer profile for normal cells.…”
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Risk assessment of complex organoarsenic species in food by EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Agneta Åkesson, Vasileios Bampidis, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Gisela Degen, Antonio Hernández‐Jerez, Tim Hofer, Christer Hogstrand, Stefano Landi, Jean‐Charles Leblanc, Kyriaki Machera, Evangelia Ntzani, Guido Rychen, Salomon Sand, Katharina Vejdovszky, Barbara Viviani, Lars Barregård, Diane Benford, Eugenia Dogliotti, Kevin Francesconi, Jose Ángel Gómez Ruiz, Hans Steinkellner, Tanja Schwerdtle

“…For AsB, no reference point (RP) could be derived because of insufficient toxicity data. AsB did not show adverse effects in the two available repeat dose toxicity tests in rodents. …”
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Integrated strategies for effective remediation of chromium-contaminated soils: Advancements, challenges, and sustainability implications by Yingying Xing, Yu Zheng, Xiukang Wang

“…Soil chromium contamination represents a significant global environmental challenge, posing serious risks to human health and ecosystems. The toxicity of hexavalent chromium, in particular, underscores the need for effective remediation strategies to mitigate its harmful effects. …”
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Novel tetracycline hybrids: synthesis, characterization, docking studies and in-vitro evaluation of antibacterial activity by Mansi Shah, Bhanubhai Suhagia, Sunita Goswami, Sneha Sagar, Arpit Patwari

“…Molecular dynamic simulation studies and in silico pharmacokinetic and toxicity prediction studies were done to determine in silico pharmacokinetics and toxicity of compounds. …”
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Complications and Influential Perioperative Factors Associated with SpaceOAR Hydrogel Placement by Kerith R. Wang, Rishabh K. Simhal, Cassra B. Clark, Mark J. Mann, James R. Mark, Costas D. Lallas, Robert Den, Edouard J. Trabulsi

“…Overall, the hydrogel placement was well tolerated with low incidence of mild and transient procedure-related toxicity.…”
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Enhancement of in vitro antitumour activity of epirubicin in HER2+ breast cancer cells using immunoliposome formulation by Farnaz Khaleseh, Abbas Hemmati Azandaryani, Fatemeh Fathian Kolahkaj, Mozafar Khazaei, Katayoun Derakhshandeh

“…The preparation process of liposomes was a modified ethanol injection method followed by Herceptin conjugation. The in vitro cell toxicity and cellular uptake of optimum formulation against HER2+ and HER2− cancer cell lines were evaluated. …”
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Safety evaluation of the food enzyme α‐amylase from the non‐genetically modified Aspergillus sp. strain FUA by EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Monika Sramkova, Henk Van Loveren, Laurence Vernis, Cristina Fernàndez‐Fraguas, Magdalena Andryszkiewicz, Natalia Kovalkovicova, Eleonora Marini, Yi Liu

“…Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by means of a repeated dose 90‐day oral toxicity study in rats. …”
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