Immunolocalization of SP22 (Park7) on the human sperm membrane is indicative of live birth by Gary R Klinefelter, Michael P Diamond, Stephen A Krawetz

“…More than twenty years have passed since we discovered a novel sperm membrane protein (SP22) derived from the Park7 gene that is highly correlated with the fertility of rat sperm exposed to epididymal toxicants. We subsequently discovered that SP22 originates in the testis and is also compromised during exposure to testicular toxicants. …”
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Aged polylactic acid microplastics with ultraviolet irradiation stunted pakchoi (Brassica chinensis L.) germination and growth with cadmium in hydroponics by Lei Sun, Ya Liu, Yakun Feng, Zequn Fan, Lei Jiang, Can Lu, Cuiling Jiang

“…The presence of biodegradable microplastics (BMPs) alongside toxic metals in soil significantly threatens plant health. …”
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Synergistic action between a synthetic cannabinoid compound and tramadol in neuropathic pain rats by Quiñonez-Bastidas Geovanna Nallely, Osuna-Martínez Ulises, Reda-Licea Ana Laura, López-Ortíz Manuel, Regla Ignacio, Navarrete Andrés

“…In the present study the interaction of cannabinoid, PhAR-DBH-Me [(R, Z)-18-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-18-oxooctadec-9-en-7-ylphenyl-acetate] and tramadol in two neuropathy models, as well as their possible toxic effects, was analyzed. The anti-allodynic effect of PhAR-DBH-Me, tramadol, or their combination, were evaluated in neuropathic rats. …”
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Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice by Ziyi Xiong, Qiling Kong, Juan Hua, Qi Chen, Dandan Wang

“…We aimed to investigate the toxic effects of polystyrene NPs on the heart and the associated mechanisms. …”
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Microplastics in food products: Prevalence, artificial intelligence based detection, and potential health impacts on humans by M. Amin Mir, Muhammad Azhar Ali Khan, Bimal Krishna Banik, Syed M. Hasnain, Lina Alzayer, K. Andrews, Sani I. Abba

“…Among the health hazards that microplastics present include oxidative stress, immune system disturbance, neurotoxicity, reproductive toxicity, and possible carcinogenic consequences. Concerns about nanoplastics' toxicity are heightened by their capacity to cross biological barriers and build up in tissues. …”
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GC–MS analysis and in silico approaches to Stichopus hermanii as anti-inflammatory through PKC-β inhibition by Kurnia Fatwati, Asmawati Amin, Lenni Indriani, Rusdina Bte Ladju, Fuad Husain Akbar, Nurlindah Hamrun

“…Through ADMET prediction tests, these compounds exhibited better pharmacokinetics activity and non- toxic.…”
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Anise and Fennel Essential Oils and Their Combination as Natural and Safe Housefly Repellents by Hataichanok Passara, Sirawut Sittichok, Cheepchanok Puwanard, Jirisuda Sinthusiri, Tanapoom Moungthipmalai, Kouhei Murata, Mayura Soonwera

“…All single and combination EOs were not toxic to the non-targets and could be considered safe, whereas α-cypermethrin was highly toxic to them. …”
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Dietary Flaxseed Oil Protects against Bleomycin-Induced Pulmonary Fibrosis in Rats by Joshua Lawrenz, Betty Herndon, Afrin Kamal, Aaron Mehrer, Daniel C. Dim, Cletus Baidoo, David Gasper, Jonathan Nitz, Agostino Molteni, Richard C. Baybutt

“…Bleomycin, a widely used antineoplastic agent, has been associated with severe pulmonary toxicity, primarily fibrosis. Previous work has shown a reduction in bleomycin-induced lung pathology by long-chain omega-3 fatty acids. …”
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Case report: Successful treatment of a thallium sulfate intoxication in a dog with use of Prussian blue by Fergal M. McDermott, Anne A. Kan, Claudine C. Hunault, Joris H. Robben, Dylan W. de Lange, Marieke A. Dijkman

“…Soluble thallium salts are highly toxic, with mortality rates exceeding 70% in animals compared to 6%−15% in humans. …”
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Harnessing Non-Antibiotic Strategies to Counter Multidrug-Resistant Clinical Pathogens with Special Reference to Antimicrobial Peptides and Their Coatings by Shyam Kumar Mishra, Tanzina Akter, Umme Laila Urmi, George Enninful, Manjulatha Sara, Jiawei Shen, Dittu Suresh, Liangjun Zheng, Elias Shiferaw Mekonen, Binod Rayamajhee, Francesco M. Labricciosa, Massimo Sartelli, Mark Willcox

“…Additionally, this review presents updates on strategies aimed at improving the cost, stability and selective toxicity of AMPs through the development of peptidomimetics. …”
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Similarities and differences in physiological adaptation to cadmium interactions with nitrogen levels between two aquatic iris life forms in urban wetlands by Zhenzuo Lei, Yuan Jiang, Yanqiong Meng, Yiyong Li, Yucong Li, Tao Hu, Yanjun Ma

“…These findings suggest that evergreen and deciduous irises employ distinct adaptive strategies to Cd toxicity; evergreen irises mitigate oxidative stress through enhanced reactive oxygen species (ROS) scavenging, whereas deciduous irises dilute Cd toxicity by increasing biomass. …”
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Zearalenone exacerbates lipid metabolism disorders by promoting liver lipid droplet formation and disrupting gut microbiota by Xiao Han, Bingxin Huangfu, Tongxiao Xu, Kunlun Huang, Xiaoyun He

“…In the absence of significant toxicity and without affecting glucose tolerance, 50 and 100 μg/kg b. w. …”
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Biological Response Modifiers in Combination with Antivirals against Experimentally-Induced Virus Infections by Robert W Sidwell, John H Huffman, Donald F Smee, John Gilbert, Roland K Robins, Meir Kende, John Huggins

“…In each experiment. multiple dosages of both BRM and ribavirin were selected to range from ineffective levels to, in certain cases with ribavirin, lethally toxic levels. Ribavirin was always administered orally twice daily for three days starting 24 h after virus inoculation. …”
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Unveiling the mechanism of micro-and-nano plastic phytotoxicity on terrestrial plants: A comprehensive review of omics approaches by Asad Jamil, Ambreen Ahmad, Muhammad Moeen-ud-din, Yihao Zhang, Yuxuan Zhao, Xiaochen Chen, Xiaoyu Cui, Yindong Tong, Xianhua Liu

“…MNPs can infiltrate plants through roots or leaves, causing a range of toxic effects, including inhibiting water and nutrient uptake, reducing seed germination rates, and impeding photosynthesis, resulting in oxidative damage within the plant system. …”
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Recent Advances in Biotechnological Methods for Wheat Gluten Immunotoxicity Abolishment – a Review by Vijole Bradauskiene, Lina Vaiciulyte-Funk, Bakht Ramin Shah, Darius Cernauskas, Mihaela Adriana Tita

“…Some of the enzymes hydrolyze gluten, others block the action of toxic protein fragments. The majority of studies were carried out using lactic acid bacteria cultures, as single strains or in consortia. …”
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Common Pokeweed by Brent Sellers, Jason Ferrell, Curtis Rainbolt

“… SS-AGR-123, a 2-page illustrated fact sheet by Brent Sellers, Jason Ferrell, and Curtis Rainbolt, provides key information on the biology, toxicity, cultural uses, and control of common pokeweed (Phytolacca americana) -- also called poke berry, pigeon berry, inkberry coakum, pocan bush, scoke, poke salad, and American nightshade. …”
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Ion Channels and Zinc: Mechanisms of Neurotoxicity and Neurodegeneration by Deborah R. Morris, Cathy W. Levenson

“…This paper discusses the role of the excitotoxic influx and accumulation of zinc, the mechanisms responsible for its cytotoxicity, and a number of disorders of the central nervous system that have been linked to these neuronal ion channels and zinc toxicity including ischemic brain injury, traumatic brain injury, and epilepsy.…”
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Cardiac Oscillations Complicating Brain Death Diagnosis by Brittany Bolt, Farid Muakkassa, Lindsay Bruening, Cameron Marcus, Brittany Cunningham, Erin Pawlak, Richard Gandee, Christopher Newey

“…We discuss here the case of a 27-year-old male who had a cardiac arrest following toxic gaseous exposure. He ultimately progressed to brain death but was identified as having cardiac oscillations during clinical assessments that complicated the diagnosis. …”
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CORRECTION OF MALNUTRITION IN CANCER P ATIENTS WITH ORAL SUPPLEMENTS (SIPING) by V. M. Khomyakov, A. D. Ermoshina

“…Malnutrition in cancer patients is associated with poorer overall survival, reduced benefit from surgical and medical therapies, increased therapy-related toxicity, poorer quality of life. Early diagnostics of malnutrition and purpose of nutritional therapy is one of important components of supportive care at all steps of anticancer treatment. …”
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Utilization of the Safe Surgical Dislocation Approach of the Hip to Retrieve a Bullet from the Femoral Head by Ruth Delaney, Maurice Albright, Gleeson Rebello

“…Retained intra-articular missiles from low-velocity handguns can lead to mechanical arthritis, synovitis, and lead toxicity. Various surgical approaches have been described to extract such foreign bodies from the hip joint. …”
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